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Translational Cancer Medicine MRes

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Translational Cancer Medicine enables you to gain detailed knowledge and understanding of research methods applied to rational drug design, clinical study design, molecular and cell biology, tumour immunology, genetics and cancer imaging. You'll gain practical experience  through two six-month laboratory rotations. 

 


Key benefits

  • A unique research programme that includes the study of advanced imaging methods and tumour immunology.

  • The sponsoring laboratories and departments all have international standing and closely supervise research trainees throughout the study programme.

  • This programme is a competitive course to support PhD applications and continued translational and medical training.  

Key information

Application status Open

Duration One year FT, September to September

Study mode Full-time

Credit value UK 180/ECTS 90

Course intake 10-14 FT

Course leaders

Dr James Arnold, Programme Lead

dora.jonsdottir@kcl.ac.uk

Further details

Course contact for further information

Postgraduate Admissions Team, Admissions Office tel: +44 (0) 20 7848 7000 fax: +44 (0) 20 7848 7200

Course contact form Postgraduate admissions

Awarding institution King's College London

Faculty Faculty of Life Sciences & Medicine

Locations

 

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Course detail

Description

The Translational Cancer Medicine MRes study pathway offers unique opportunities for you to join experienced research teams and work on particular projects from the outset. This course will allow you to develop an in-depth understanding of research methods, and of how theoretical academic studies and skills relate to research projects.

You will explore Fundamentals of Translational Cancer Medicine, providing you with advanced knowledge and skills to conceptualise, design, conduct and critically appraise specialist research. You will gain hands on research experience in two six month lab projects. 

Examples or research project titles could include:

 

Discipline

Supervisor

Project title

Epidemiology

Dr Mieke Van Hemelrijck

Serum biomarkers in relation to risk and progression of cancer – an analysis using the Swedish Apolipoprotein MORtality RISk study (AMORIS

Cancer Bioinformatics

Dr Anita Grigoriadis & Dr Cheryl Gillett

Characterisation of different immune cells in lymph nodes

Cancer Bioinformatics

Dr Anita Grigoriadis

Analysing the immune phenotypes in lymph nodes with transcriptomic and imaging data

Cancer functional genomics, computational biology

Dr Francesca Ciccarelli

Validation of actionable genes in colorectal cancer

Cancer Cell Biology

Dr James Arnold

Tumour associated macrophages and their interaction with CD8+ T cells in cancer

Cancer Cell Biology

Dr James Arnold

Tumour associated macrophages in cancer progression 

Cancer Cell Biology

Dr Jeremy Carlton

Regulation of cell division and receptor degradation by the ESCRT-machinery 

Cancer Cell Biology

Dr Gilbert Fruhwirth

Multi-modal in vivo imaging for monitoring cancer treatment

Cancer Cell Biology

Dr Claire Wells

Exploring the fesability of using nucleolin as a drug target

Cancer Cell Biology

Dr Claire Wells Investigating the role of PKN3 activity during triple negative breast cancer cell invasion

Imaging 

Prof Vicky Goh &
Prof Gary Cook

Optimising multimodality treatment response assessment with imaging

Cancer Cell Biology & Imaging

Prof Tony Ng

cMet/ErbB and exosomes in non-small cell lung cancer

Imaging

Prof Vicky Goh & Prof Gary Cook

Optimising multimodality treatment response assessment with imaging

Cancer Head/Neck

Prof Mahvash Tavassoli

Predictive Biomarkers of Treatment Resistance in Head and Neck Squamous Cell Carcinoma

Molecular Pathology

Prof Sarah Pinder

Molecular pathology of breast cancer precursors

Haemato-oncology

Prof Farzin Farzaneh & Dr Kiki Ioannou

High throughput analysis of modulators of cellular immunity against  cancer associated antigens

Haemato-oncology

Dr Alan Ramsay

Investigating the tumour microenvironment (TME) and immune suppression  in lymphoma

Haemato-oncology

Prof Francesco Dazzi

Tumour associated stroma and therapeutic targets

Haemato-oncology

Prof Ghulam Mufti

Truncal vs branch mutations in MDS/AML

Haemato-oncology

Prof Ghulam Mufti

Immune response in aplastic anaemia

Tumour Immunology

Prof Joy Burchell

Changes in post-translational modifications (O-linked glycosylation)  of breast cancer: The effect on tumour behaviour and immune recognition

Tumour Immunology

Prof Tony Ng & Dr Ryan Green 

Investigations of the impact of EGFR/HER3 treatments on the cancer: immune stromal microenvironment interface – via RNA-binding protein FUS

Tumour Immunology

Prof Tony Ng & Dr Ryan Green 

Investigations of the impact of EGFR/HER3 treatments on the cancer: immune stromal microenvironment interface – via exosomal transfer 

Tumour Immunology

Dr Sophia Karagiannis &
Dr Mieke Van Hemelrijck

Associations between IgE and atopy and the development of prostate and gyneacological cancers

Clinical Tumour Immunology

Dr Debashis Sarker &
Dr James Spicer

 Factors affecting patient recruitment and experience in Phase 1 trials

Clinical Tumour Immunology

 

Dr Debashis Sarker &
Dr Aamir Ahmed

 Role of Wnt Signalling in Pancreatic Ductal Adenocarcinoma

Tumour Immunology

Dr John Maher

Genetic targeting of T-cells against cancer

Cancer Immunology 

Dr Sophie Papa

Targeting SF-25 with CAR T-cells

Stem Cells and Bone Cancer

Prof Agamemnon Grigoriadis

Mechanisms of bone tumour growth and metastasis

Breast Cancer Imagaing 

Prof Arnie Purushotham

FORCE/Tissue Stresses of Cance

Breast Cancer Genetic 

Dr Elinor Sawyer

Survival analysis of the GLACIER study and association of breast cancer risk factors and predisposition SNPs with lobular breast cancer survival

Cancer Studies 

Dr Shahram Kordasti 

The role of CD95+ Tregs in controlling autoimmunity 

Leuukemia Biology

Prof Eric So 

Studying of cancer cell heterogeneity in human AML 

 

Further literature

Course format and assessment

Teaching

We use lectures, seminars and group meetings to deliver most of the modules on the course. 

On average teaching consists of:

  • 40 hours of lectures
  • 1.5 – 3 hours per week of Lab/group meetings (depending on projects)
  • supervision/feedback during each lab roation

You will also be expected to undertake a significant amount of independent study.

Typically, 1 credit equates to ten hours of work.

Throughout the year, you will also attend literature reviews and journal clubs that the labs/departments organise, as well as any other internal or external seminars deemed relevant to your projects/assignments.

Assessment

The primary method of assessment for this course is a combination of written essays, a thesis (research report), a presentation/Q&A session regarding the research report and a draft of a scientific paper.

The study time and assessment methods detailed above are typical and give you a good indication of what to expect.  However, they are subject to change. 

Extra information

Occupational health clearance will be required for some of the projects.

Structure

Year 1

Courses are divided into modules. You will normally take modules totalling 180 credits.
Required Modules

You are required to take:

We regularly review our modules to make sure our programmes are as up-to-date, innovative and relevant as possible. The modules we offer may therefore change. We suggest that you check the course finder for updates: http://www.kcl.ac.uk/study/postgraduate/index.aspx

Optional Modules

Entry requirements & how to apply

Entry requirements
Minimum UK requirements  

First class or high 2:1 BSc (honours) degree or overseas equivalent in biomolecular or physical sciences.

MBBS students can be admitted at any time following the third year of their programme. Post-year three: entry is based on year three performance plus evidence of knowledge of the basic elements of translational research topics. Advanced years (four to five): students must complete their current year of study. External students need to obtain permission from their own medical school and provide evidence of their exam performance in the pre-clinical examinations.

International requirements   Visit our admissions webpages to view our International entry requirements.
English Language requirements Band D Visit our admissions webpages to view our English language entry requirements.

 

Application procedure

Applications must be made online using King’s online application portal apply.kcl.ac.uk and a non-refundable application fee of £55 applies.

Applications for 2017 entry are now closed.

Personal statement and supporting information

You will be asked to submit the following documents in order for your application to be considered:

Document checklist
Personal Statement Yes A personal statement of up to 4,000 characters (maximum 2 pages) is required. Please detail your research experience and any previous laboratory experience. Include your reason for applying and career aims. Please specify two areas of interest from the list of projects in the description. MBBS students should provide a statement demonstrating knowledge of basic elements of translational research topics such as epidemiology, clinical biostatistics and clinical pharmacology (relating to drug discovery).  
Previous Academic Study  Yes A copy (or copies) of your official academic transcript(s), showing the subjects studied and marks obtained. If you have already completed your degree, copies of your official degree certificate will also be required. Applicants with academic documents issued in a language other than English, will need to submit both the original and official translation of their documents.
References Yes Two references are required with at least one academic. Professional references will be accepted if you have completed your qualifications over five years ago.
Other Optional You may wish to include a CV (Resume) or evidence of professional registration as part of your application.

 

Application closing date

We recommend that you submit your application as soon as possible.  Our first application deadline is the 30th March 2018.  Applications will remain open if places are available and programmes will be closed as soon as they are full.  For programmes with spaces remaining, no further applications will be accepted from non-EU (Overseas) nationals after 27th July 2018 or from UK/ EU nationals after 31st August 2018.

Help and support

If you don't have a suitable qualification for direct entry to a UK university, or if English isn't your first language, our academic preparation courses can help you get ready for study in the UK.

Preparation courses

Fees and funding

  • Full time UK fees: £10,950 p.a. (2017/18)*
  • Full time overseas fees: £22,800 p.a. (2017/18)

Please note: Current regulations allow some students to pay UK tuition fees on the basis of their EU citizenship or residency. Until these eligibility criteria are changed, the EU tuition fee will remain the same as the UK tuition fee. 

*These tuition fees may be subject to additional increases in subsequent years of study, in line with King’s terms and conditions.

Deposit

When you receive an offer for this course you will be required to pay a non-refundable deposit to secure your place. The deposit will be credited towards your total fee payment.

The UK/EU deposit is £500.

The INTERNATIONAL deposit is £2,000. 

  • If you receive an offer on or before 31st March 2017, payment is due by 30th April 2017.
  • If you receive an offer between 1st April 2017 and 30th June 2017, payment is due within one month of receiving the offer.
  • If you receive an offer between 1st July 2017 and 31st July 2017, payment is due within two weeks of receiving the offer.
  • If you receive an offer on or after 1st August 2017, payment is due within one week of receiving the offer.

If you are a current King’s student in receipt of the King's Living Bursary you are not required to pay a deposit to secure your place on the programme. Please note, this will not change the total fees payable for your chosen programme.

Additional costs/expenses

In addition to the costs above, you can also expect to pay for:

  • Books if you choose to buy your own copies
  • Clothing for optional course related events and competitions
  • Library fees and fines
  • Personal photocopies
  • Printing course handouts
  • Society membership fees
  • Stationery
  • Graduation costs
  • Travel costs for travel around London and between campuses

Please visit our web pages on fees and funding for more information.

Financial help and support

Visit the fees and funding webpages to find out more about bursaries, scholarships, grants, tuition fees, living expenses, student loans and other financial help available at King's.

Career prospects

Future PhD studies. Clinical and non-clinical academic careers in cancer medicine.

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Next steps

View our postgraduate guide

Learn more about postgraduate degree programmes at King's. Download or view our guide in PDF format.

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