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Prof Thalia Eley BA PhD

Thalia Eley

 

 

 

 

 

 

 

 

 

 

 

Professor of Developmental Behavioural Genetics

EDIT Lab Director


E: thalia.eley@kcl.ac.uk

Biography

  • Professor of Developmental Behavioural Genetics, SGDP Centre, Institute of Psychiatry, King’s College London (2013 to present).
  • Reader in Developmental Behavioural Genetics, SGDP Centre, Institute of Psychiatry, King’s College London (2009 to 2013).
  • Senior Lecturer, SGDP Centre, Institute of Psychiatry, King’s College London (2008-2009).
  • Medical Research Council Research Fellow with status of Senior Lecturer, SGDP Centre, Institute of Psychiatry, King’s College London (2002-2008).
  • Medical Research Council Research Training Fellow with status of Lecturer, SGDP Centre, Institute of Psychiatry, KCL (1999-2002).
  • Post-doctoral research worker (Twins’ Early Development Study), SGDP Centre, Institute of Psychiatry, KCL (1996-1998).

Research overview

My work focuses on exploring interplay between genes and the environment with respect to the development and treatment of anxiety and depression, particularly in young people. I have always been fascinated by the fact that different people react so differently from one another when under stress. In my research I use both twin studies, in order to estimate the relative contribution of genes and the environment, and also molecular genetic approaches, which can identify links between specific genes and outcomes of interest. I also draw on methods used in experimental psychology to explore aspects of information processing that may be relevant mechanisms when trying to understand the role of genes and the environment on the development and treatment of anxiety and depression. 

For an overview of Professor Eley’s therapygenetics work please watch her talk at the Karolinska Institute here, 2017.

For a brief overview of Professor Eley’s work please watch her talk at the IoPPN Parade of Stars, 2013.

For a more in depth summary of her whole research programme, you can watch her 2014 inaugural lecture here.

Projects

Therapygenetics
Twin and Children of Twin Studies
Information Processing Studies

Media


June 2017

All in the Mind: Parent's self stigma and mental health; First impressions; Mental health manifestos; Insiders' Guide
BBC Radio 4's Claudia Hammond meets Professor Cathy Creswell and Thalia Eley to discuss their extensive practical research helping parents to deal with their child's anxiety.

June 2016
Interview with Motherboard on research in therapygenetics and the EDITLab

Awards

First paper on "Therapygenetics" awarded the Macquarie University Excellence in Research Award, 2011

http://www.mq.edu.au/researchawards/winners/winners-2011.html

Here is a short clip of our collaborator Jennie Hudson, who treated many of the children in the project talking about this work to celebrate this award:

http://www.youtube.com/watch?v=q8WDjrmhtF0&feature=BFa&list=PL18AF7B46466E711D

Pierre Janet Award, 2005 (International Society for the Study of Dissociation)

Lilly-Molecular Psychiatry Award, 2004 (for best original research by a young investigator)

British Psychological Society Spearman Medal, 2002 (for outstanding published work in psychology within 10 years of graduation) 

Funded Grants (past 5 years)

  1. Exploring social factors in the psychological treatment of anxiety and mood disorders, ESRC LISS DTP Case Studentship, October 2017-October 2021. Lead Supervisor: Thalia Eley. Second Academic Supervisor: Andrea Danese. Partner: Kumar Jacobs from MindWave
  2. Intergenerational Transmission of Risk for Common Mental Disorders: A Longitudinal Extended Children-of-Twins Cohort Study, The Research Council of Norway Independent basic research projects - Medicine, Health Sciences and Biology (FRIMEDBIO), December 2017 – December 2020, £38,521.21. Principal Investigator: Eivind Ystrøm, KCL Subcontract Principal Investigator: Tom McAdams. Co-investigators: Thalia Eley, Fruhling Rijsdijk.
  3. Prediction of response to psychological therapy in anxiety and depressive disorders from clinical, demographic and genetic factors, Fondation Peters, October 2015-October 2019, £140,000. Principal investigator: Thalia Eley; Co-investigator: Gerome Breen.
  4. Origins of learning difficulties and behaviour problems: From behavioural genetics to behavioural genomics, MRC Progamme Grant (MR/M021475/1), October 2015-October 2020, £1,597,091 (FEC £2,665,695). Principal investigator: Robert Plomin. Co-investigators: Thalia Eley (10%), Emily Simonoff, Philip Dale,Gerome Breen, Paul McCrone. 
  5. Cumulative genetic plasticity as a predictor of psychological treatment response: Cognitive behaviour therapy for child anxiety disorders, Jacobs Foundation Project Grant, June 2014-December 2016, £25,970. Principal investigator: Kathryn Lester; Co-Investigator: Thalia Eley.
  6. Genome-wide expression change over the course of exposure-based psychological therapy, Biomedical Research Centre and Dementia Unit Experimental Clinical Trials Pilot Funding Awards 2013-2014, January 2014-March 2014, £24,000. Principal investigator: Thalia Eley; Co-investigators: Kathryn Lester, Gerome Breen, Richard Dobson.
  7. The emotional health project: understanding and preventing anxiety and depression in girls, Australian Research Council Linkage Grant, (LP130100576), February 2014-February 2017, $341,484 (Australian dollars, subcontract to IoP, KCL of £75,347). Chief investigators: Jennifer Hudson, Carol Newall and Ron Rapee. Principal investigator of genetic sub-contract: Thalia Eley.
  8. MRC Population Health Scientist Fellowship (MR/K021281/1), July 2013-July 2016, £270,776 (FEC £338,470). Fellow: Rob Keers, Supervisors: Thalia Eley and Cathryn Lewis.
  9. MRC Centenary Early Career Award: Adjunct to MRC New Investigator Research Grant (G0901874), Sept 2012-Aug 2014, £80,000 (FEC £100,000). Principal (sole) Investigator: Thalia Eley.
  10. Understanding genetic and environmental risks of emotional disorders in childhood and adolescence. Australian Research Council (FT120100217). July 2012-July 2016, $794,124 (Australian dollars). Principal investigator/Fellow: Jennifer Hudson. Status: Named collaborator.
  11. Attention Bias Modification (ABM): Development and testing of a school-based “Cognitive Vaccine” for the reduction and prevention of child anxiety (MR/J011762/1), MRC, September 2012-September 2014, £240,869 (FEC £298,557). Principal investigator: Thalia Eley; Co-investigator: Kathryn Lester.
  12. Familial transmission of emotional development: A child of twins approach. Leverhulme Trust (RPG-210), March 2012-March 2015, £195,440. Principal Investigator: Thalia Eley. Co-investigators: Paul Lichtenstein, Jenae Neiderhiser, Jurgita Narusyte.
  13. DNA methylation and adolescent depression: an MZ differences study. Psychiatry Research Trust, September 2011-September 2013, £47,800. Principal investigator: Thalia Eley; Co-investigators: Jonathan Mill and Emma Dempster.
  14. International Study of Genetic Factors in Exposure Treatments of Anxiety Disorders. Alexander von Humboldt-Foundation, Sept 2011-Sept 2016, £301,248. Sub-contract from an award made to Prof Jürgen Margraf. Principal investigator of genetic sub-contract: Thalia Eley.
  15. The role of antisocial friends in the development of adolescent antisocial behaviour. ESRC post-doctoral fellowship (ES/I036524/1), June 2011-June 2012, £85,328 (FEC £108,978). Fellow: Thomas McAdams, Supervisor: Thalia Eley.
  16. Exploring the development of anxiety in young people: a combined social, genetic and cognitive approach. ESRC PhD studentship, Sept 2010-Sept 2014, £82,000. Supervisors: Thalia Eley (primary) & Julie Hadwin (secondary), Student: Hannah Brown.
  17. Use of parental DNA in genetic analyses of child anxiety disorders. BRC biomedical technologies, Sept 2010-Sept 2012, £36,000. Principal Investigator: Thalia Eley.

Key Publications

  1. Eley, T. C.*, McAdams, T. A.*, Rijsdijk, F. V., Lichtenstein, P., Narusyte, J., Reiss, D., Spotts, E., Ganiban, J., Neiderheiser, J. M. (2015). The intergenerational transmission of anxiety: a children-of-twins study. American Journal of Psychiatry, 172(7), 630-637. http://ajp.psychiatryonline.org/doi/10.1176/appi.ajp.2015.14070818 
  2. Eley, T. C., Hudson, J. L., Creswell, C., Tropeano, M., Lester, K. J., Cooper, P., Farmer, A., Lewis, C. M., Lyneham, H. J., Rapee, R.M ., Uher, R., Zavos, H. M. S., & Collier, D. A. (2012). Therapygenetics: The 5HTTLPR and response to psychological therapy. Molecular Psychiatry, 17, 236-237. Link:http://dx.doi.org/10.1038/mp.2011.132
  3. Eley, T. C., Napolitano, M., Lau, J. Y. F., & Gregory, A. M. (2010). Does childhood anxiety evoke maternal control? A genetically informed study. Journal of Child Psychology & Psychiatry, 51, 772-779. Link:http://dx.doi.org/10.1111/j.1469-7610.2010.02227.x
  4. Eley, T. C., Gregory, A. M., Lau, J. Y.F ., McGuffin, P., Napolitano, M., Rijsdijk, F. V., & Clark, D. M. (2008). In the face of uncertainty: A twin study of ambiguous information, anxiety and depression in children. Journal of Abnormal Child Psychology, 36, 55-65. Link:http://dx.doi.org/10.1007/s10802-007-9159-7
  5. Lau, J. Y. F. & Eley, T. C. (2008). Disentangling gene-environment correlations and interactions on adolescent depressive symptoms. Journal of Child Psychology & Psychiatry, 42,142-150. Link:http://dx.doi.org/10.1111/j.1469-7610.2007.01803.x
  6. Eley, T. C., Gregory, A. M., Clark, D. M., & Ehlers, A. (2007). Feeling anxious: A twin study of panic/somatic symptoms, anxiety sensitivity and heart-beat perception in children. Journal of Child Psychology and Psychiatry, 48, 1184-1191. Link:http://dx.doi.org/10.1111/j.1469-7610.2007.01838.x
  7. Eley, T. C., Sugden, K., Gregory, A. M., Sterne, A., Plomin, R., & Craig, I. W. (2004). Gene-environment interaction analysis of serotonin system markers with adolescent depression. Molecular Psychiatry, 9, 908-918. (Awarded the Lilly-Molecular Psychiatry Award 2004). Link:http://dx.doi.org/10.1038/sj.mp.4001546
Publications

 In Press


  1. Hannigan, L. J., Rijsdijk, F., Ganiban, J. M., Reiss, D., Spotts, E. L., Neiderhiser, J. M., McAdams, T. A., Eley, T. C. (2017). Shared genetic influences do not explain the association between parent-offspring relationship quality and offspring internalizing problems: results from a Children-of-Twins study. Psychological Medicine.
  2. Coleman, J. R. I., Lester, K. J., Keers, R., Munafò, M. R., Breen, G., & Eley, T. C. (2017). Genome-wide association study of facial emotion recognition in children and association with polygenic risk for mental health disorders. American Journal of Medical Genetics Part B: Neuropsychiatric Geneticsdoi: 10.1002/ajmg.b.32558
  3. Roberts, S., Wong, C. C. Y., Breen, G., Coleman, J. R., De Jong, S., Jöhren, P., Keers, R., Curtis, C., Lee, S. H., Margaf J., Schneider, S., Teismann, T., Wannemüller, A., Lester, K., Eley, T. C. (2017). Genome-wide expression and response to exposure-based psychological therapy for anxiety disorders. Translational Psychiatry.
  4. Coleman, J. R. I., Lester, K. J., Keers, R., Munafò, M. R., Breen, G., & Eley, T. C. (2017). Genome-wide association study of non-verbal emotion recognition in a population cohort of children, and association with polygenic risk for mental health disorders. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics.
  5. Denis, D., Akhtar, R., Holding, B., Murray, C., Panatti, J., Claridge, G. Sadeh, A., O’Leary, R., Maughan, B., McAdams, T. A., Rowe, R., Eley, T. C., Viding, E., Gregory, A. M. (2017). Externalising behaviours and callous-unemotional traits: Different associations with sleep quality. Sleep.
  6. Hannigan, L. J., McAdams, T. A., & Eley, T. C. (2017). Developmental change in the association between adolescent depressive symptoms and the home environment: results from a longitudinal, genetically-informative investigation. Journal of Child Psychology and Psychiatry.
  7. Lester, K. J., Coleman, J. R. I., Roberts, S., Keers, R., Breen, G., Bögels, S., Creswell, C., Hudson, J. L., McKinnon, A., Nauta, M., Rapee, R. M., Schneider, S., Silverman, W. K., Thastum, M., Waite, P., Wegeland, G. J. H., Eley, T. C. (2016). Genetic variation in the endocannabinoid system and response to Cognitive Behavior Therapy for child anxiety disorders. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics.
(Past 5 years)

  1. Bogl, L.-H., Jelenkovic, A., Vuoksimaa, E., Ahrenfeldt, L., Pietiläinen, K. H., Stazi, M. A., Fagnani, C., D'Ippolito, C., Hur, Y., Jeong, H., Silber, J. L., Eaves, L. J., Maes, H. H., Bayasgalan, G., Narandali, D., Cutler, T. L., Kandler, C., Jang, K. L., Christensen, K., Skytthe, A., Kyvik, K. O., Cozen, W., Hwang, A. E., Mack, T. M., Derom, C. A., Vlietnck, R. F., Nelson, T. L., Whitfield, K. E., Corley, R. P., Huibregste, B. M., McAdams, T. A., Eley, T. C., Gregory, A. M., Krueger, R. F., McGue, M., Pahlen, S., Wilemsen, G., Bartels, M., vam Beijsterveldt, T. C. E. M., Pang, Z., Tan, Q., Martin, N., Medland, S. E., Mongtomery, G. W., Hjelmborg, J. v. B., Rebato, E., Swan, G. E., Krasnow, R., Busjahn, A. Lichtenstein, P., Öncel, S. Y., Aliev, F., Baker, L. A., Tuvblad, C., Siribaddana, S. h., Sumathipala, A., Rijsdijk, F., Magnusson, P. K. E., Pedersen, N. L., Dahl Aslan, A. K., Ordoña, J. R., Sánchez-Romera, J. F., Colodro- Conde, L., Duncan, G. E., Buchwald, D., Tarnoki, A. D., Tarnoki, D. L., Yokoyama, Y., Hopper, J. L., Loos, R. J. F., Boomsma, D., Sørensen, T. I. A., Silventoinen, K., Jaakko, Kaprio, J. (2017). Does the sex of one’s co-twin affect height and BMI in adulthood? A study of dizygotic adult twins from 31 cohorts. Biology of sex differences, 8(1), 14. doi: 10.1186/s13293-017-0134-x
  2. Culverhouse, R. C., Saccone, N. L., Horton, A. C., Ma, Y., Anstey, K. J., Banaschewski, T., Burmeister, M. Cohen-Woods, S. Etain, B. Fisher, H. L. Goldman, N. Guillaume, S. Horwood, J. Juhasz, G. Lester, K. J. Mandelli, L. Middeldorp, C. M. Olie, E. Villafuerte, S. Air, T. M. Araya, R. Bowes, L. Burns, R. Byrne, E. M. Coffey, C. Coventry, W. L. Gawronski, K. A. B. Glei, D. Hatzimanolis, A. Hottenga, J. J. Jaussent, I. Jawahar, C. Jennen-Steinmetz, C. Kramer, J. R. Lajnef, M. Little, K. zu Schwabedissen, H. M. Nauck, M. Nederhof, E. Petschner, P. Peyrot, W. J. Schwahn, C. Sinnamon, G. Stacey, D. Tian, Y. Toben, C. Van der Auwera, S. Wainwright, N. Wang, J. C. Willemsen, G. Anderson, I. M. Arolt, V. Aslund, C. Bagdy, G. Baune, B. T. Bellivier, F. Boomsma, D. I. Courtet, P. Dannlowski, U. de Geus, E. J. C. Deakin, J. F. W. Easteal, S. Eley, T. Fergusson, D. M. Goate, A. M. Gonda, X. Grabe, H. J. Holzman, C. Johnson, E. O. Kennedy, M. Laucht, M. Martin, N. G. Munafo, M. R. Nilsson, K. W. Oldehinkel, A. J. Olsson, C. A. Ormel, J. Otte, C. Patton, G. C. Penninx, B. W. J. H. Ritchie, K. Sarchiapone, M. Scheid, J. M. Serretti, A. Smit, J. H. Stefanis, N. C. Surtees, P. G. Volzke, H. Weinstein, M. Whooley, M. Nurnberger Jr, J. I. Breslau, N., Bierut, L. J. (2017). Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression. Molecular Psychiatry. doi: 10.1038/mp.2017.44
  3. Coleman, J. R. I., Lester, K. J., Roberts, S., Keers, R., Lee, S. h., De Jong, S, Gaspar, H., Teismann, T., Wannermüller, A., Schneider, S., Jöhren, P., Margraf, J., Breen, G., Eley, T. C. (2017). Separate and combined effects of genetic variants and pre-treatment whole blood gene expression on response to exposure-based cognitive behavioural therapy for anxiety disorders. The World Journal of Biological Psychiatry, 18(3), 215-226. doi: 10.1080/15622975.2016.1208841
  4. McAdams, T. A., Rijsdijk, F. V., Narusyte, J., Ganiban, J. M., Reiss, D., Spotts, E Neiderhiser, J., M., Lichtenstein, P. Eley, T.C. (2017). Associations between the parent–child relationship and adolescent self-worth: a genetically informed study of twin parents and their adolescent children. Journal of Child Psychology and Psychiatry, 58(1), 46-54. doi: 10.1111/jcpp.12600
  5. Jelenkovic, A. Hur, Y.,  Sund, R., Yokoyama, Y., Siribaddana, S. H.,  Hotopf, M., Sumathipala, A., Rijsdijk, F., Tan, Q., Zhang, D., Pang, Z., Aaltonen, S., Heikkilä, K.,  Öncel, S. Y.,  Aliev, F., Rebato, E., Tarnoki, A. D., Tarnoki, D. L.,  Christensen, K.,  Skytthe, A., Kyvik, K. O., Silberg, J. L.,  Eaves, L. J.,  Maes, H. H.,  Cutler, T. L.,  Hopper, J. L.,  Ordoñana, J. R., Sánchez-Romera, J. F.,  Colodro-Conde, L., Cozen, W.,  Hwang, A. E., Mack, T. M., Sung, J., Song, Y., Yang, S., Lee, K.,  Franz, K. E., Kremen, W. S.,  Lyons, M. J.,  Busjahn, A., Nelson, T. L., Whitfield, K. E., Kandler, C., Jang, K. L.,  Gatz, M., Butler, D. A., Stazi, M. A., Fagnani, C., D'Ippolito, D., Duncan, G. E., Buchwald, D., Derom, C. A.,  Vlietinck, R. F., Loos, R. J. F., Martin, N. G., Medland, S. E., Montgomery, G. W., Jeong, H., Swan, G. E., Krasnow, R., Magnusson, P. K. E., Pedersen, N. L., Dahl-Aslan, A. K., McAdams, T. A., Eley, T. C., Gregory, A. M., Tynelius, P., Baker, L. A., Tuvblad, C.,  Bayasgalan, G., Narandalai, D., Lichtenstein, P., Spector, T.D., Mangino, M., Lachance, G., Bartels, M., van Beijsterveldt, T. C. E. M., Willemsen, G., Burt, S. A., Klump, K. L., Harris, J. R., Brandt, I., Sevenius Nilsen, T.,  Krueger, R. F.,  Matt McGue, Shandell Pahlen, Robin P. Corley, Jacob v B. Hjelmborg, Jack H. Goldberg, Yoshinori Iwatani, Watanabe, M., Honda, C., Inui, F., Rasmussen, F., Huibregtse, B. M., Boomsma, D. I., Sørensen, T. I. A., Kaprio, J., Silventoinen, K.. (2016) Genetic and environmental influences on adult human height across birth cohorts from 1886 to 1994. eLife, 5, e20320. doi: 10.7554/eLife.20320

     

  6. Coleman JRI, Lester KJ, Roberts S, Keers R, Lee SH, De Jong S, Gaspar, H., Teisman, T., Wannemüller, A., Schneider, S., Jöhren, P., Margraf, J., Breen, G. & Eley, T.C. (2016) Separate and combined effects of genetic variants and pre-treatment whole blood gene expression on response to exposure-based cognitive behavioural therapy for anxiety disorders. The World Journal of Biological Psychiatry, 1-12. doi.org/10.1080/15622975.2016.1208841
  7. Pardiñas, A. F., Holmans, P., Pocklington, A. J., Escott-Price, V., Ripke, S., Carrera, N., Legge, S.E., Bishop, S., Cameron, D., Hamshere, M.L., Han, J., Hubbard, L., Lynham, A., Mantripragada, K., Rees, E., MacCabe, J., H., McCaroll, S. A., Baunde, B. T., Breen, G., Byrne, E.M., Dannlowski, U., Eley, T.C., Hayward, C., Martin, N.G., McIntosh, A.M., Plomin, R., Porteous, D.J., Wray, N.R., Collier, D.A., Rujescu, D., Kirov, G., Owen, M.J., Donovan, M.C., Walters, J.T.R. (2016). Common schizophrenia alleles are enriched in mutation-intolerant genes and maintained by background selection. bioRxiv. doi: 10.1101/068593
  8. Silventoinen, K., Jelenkovic, A. Sund, R., Hur, Y., Yokoyama, Y. Honda, C., Hjelmborg, J. vB., Möller, S., Ooki, S. Aaltonen, S., Ji, F., Ning, F. Pang, Z. Rebato, E., Busjahn, A., Kandler, C., Saudino, K. J., Jang, K. L., Cozen, W. Hwang, A., E., Mack, T., M., Gao, W., Yu, C., Li, L., Corley, R. P., Huibregste, B., M., Christensen, K., Skytthe, A., Kyvik, K., O., Derom, C. A., Vlietinck, R. F., Loos, R., J., F., Heikkilä, K., Wardle, J., Llewellyn, C., H., Fisher, A., McAdams, T. A., Eley, T.C., Gregory, A. M., He, M., Ding, X., Bjerregaard-Andersen, M., Beck-Nielsen, H. Sodemann, M., Tarnoki, A., D., Stazi, M., A., Fagnani, C., D'Ippolito, C., Knafo-Noam, A., Mankuta, D., Abramson, L., Burt, S. A., Silberg, J. L., Eaves, L., J., Maes, H., H., Krueger, R., F., McGue, M., Pahlen, S., Gatz, M., Butler, D., A., Bartels, M., Van Beijsterveldt, T., C., E., M., Craig, J., M., Saffery, R., Freitas, D., L., Maia, J., A., Dubois, L., Boivin, M., Brendgen, M., Dionne, G., Vitaro, F., Martin, N., G., Medland, S., E., Montgomery, G., W., Chong, Y., Swan, G. E., Krasnow, R., Magnusson, P., K., E., Pedersen, N., L., Tynelius, P., Lichtenstein, P., Haworth, C., M., A., Plomin, R., Bayasgalan, G., Narandalai, D., Harden, K. P., Tucker-Drob, E., M., Öncel, S., Y., Aliev, F., Spector, T., Mangino, M., Lachance, G., Baker, L. A., Tuvblad, C., Duncan, G., E., Buchwald, D., Willemsen, G., Rasmussen, F., Goldberg, J., H., Sørensen, T., I., A., Boomsma, D., I., Kaprio, J. (2016). "Genetic and environmental effects on body mass index from infancy to the onset of adulthood: an individual-based pooled analysis of 45 twin cohorts participating in the COllaborative project of Development of Anthropometrical measures in Twins (CODATwins) study." The American Journal of Clinical Nutrition, 104, 371-379.doi.org/10.3945/​ajcn.116.130252

  9. Hannigan, L. J., Walaker, N., Waszczuk, M. A., McAdams, T., & Eley, T.C. (2016). Aetiological influences on stability and change in emotional and behavioural problems across development: a systematic review. Psychopathology Review, 1–57. doi.org/10.5127/pr.038315
  10. Keers, R., Coleman, J., Lester, K., Roberts, S., Breen, G., & Thastum, M., Bogels, S., Schneider, S., Heiervang, E., Meiser-Stedman, R., Nauta, M.H., Creswell, C., Thirlwall, K.,  Rapee, R.M., Hudson, J.L., Lewis, C., Plomin, R., Eley, T.C. (2016). A genome-wide test of the differential susceptibility hypothesis reveals a genetic predictor of differential response to psychological treatments for child anxiety disorders. Psychotherapy and Psychosomatics: doi: 10.1159/000444023
  11. Zavos, H.M.S., Eley, T.C., McGuire, P., Plomin, , R., Cardno, A.G., Freeman, D., Ronald, A. (2016). Shared etiology of psychotic experiences and depressive symptoms in adolescence: a Longitudinal Twin Study. Schizophrenia bulletin, 42(5), 1197-1206. doi: 10.1093/schbul/sbw021.
  12. Jelenkovic, A., Sund, R., Hur, Y., Yokoyama, Y., Hjelmborg, J. V. B., Möller, S., Honda, C., Magnusson, P. K. E., Pedersen, N. L., Ooki, S., Aaltonen, S., Stazi, M. A., Fagnani, C., D’Ippolito, C., Freitas, D. L., Maia, J. A., Ji, F., Ning, F., Pang, Z., Rebato, E., Busjahn, A., Kandler, C., Saudino, K. J., Jang, K. L., Cozen, W., Hwang, A. E., Mack, T. M., Gao, W., Yu, C., Li, L., Corley, R. P., Huibregtse, B. M., Derom, C. A., Vlietinck, R. F., Loos, R. J. F., Heikkilä, K., Wardle, J., Llewellyn, C. H., Fisher, A., McAdams, T. A., Eley, T. C., Gregory, A. M., He, M., Ding, X., Bjerregaard-Andersen, M., Beck-Nielsen, H., Sodemann, M., Tarnoki, A. D., Tarnoki, D. L., Knafo-Noam, A., Mankuta, D., Abramson, L., Burt, S. A., Klump, K. L., Silberg, J. L., Eaves, L. J., Maes, H. H., Krueger, R. F., McGue, M., Pahlen, S., Gatz, M., Butler, D. A., Bartels, M., van Beijsterveldt, T. C. E. M., Craig, J. M., Saffery, R., Dubois, L., Boivin, M., Brendgen, M., Dionne, G., Vitaro, F., Martin, N. G., Medland, S. E., Montgomery, G. W., Swan, G. E., Krasnow, R., Tynelius, P., Lichtenstein, P., Haworth, C. M. A., Plomin, R., Bayasgalan, G., Narandalai, D., Harden, K. P., Tucker-Drob, E. M., Spector, T., Mangino, M., Lachance, G., Baker, L. A., Tuvblad, C., Duncan, G. E., Buchwald, D., Willemsen, G., Skytthe, A., Kyvik, K. O., Christensen, K., Öncel, S. Y., Aliev, F., Rasmussen, F., Goldberg, J. H., Sørensen, T. I. A., Boomsma, D. I., Kaprio, J. and Silventoinen, K. (2016) Genetic and environmental influences on height from infancy to early adulthood: An individual-based pooled analysis of 45 twin cohorts. Sci. Rep., 6, 28496. doi: 10.1038/srep28496
  13. Waszczuk, M., Coulson, A., Gregory, A., & Eley, T. (2016). A longitudinal twin and sibling study of the hopelessness theory of depression in adolescence and young adulthood. Psychological Medicine, 46, 1935-1949. doi: 10.1017/s003329171600048
  14. Hannigan, L. J., Mcadams, T. A., Plomin, R., & Eley, T. C. (2016). Etiological Influences on Perceptions of Parenting: A Longitudinal, Multi-Informant Twin Study. Journal of youth and adolescence, 45(12), 2387-2405. doi:10.1007/s10964-016-0419-0
  15. Lester*, K. J., Roberts*, S., Keers, R., Coleman, J. R. I., Breen, G., Wong, C. C. Y., Xu, X., Arendt, K., Blatter-Meunier, J., Bögels, S., Cooper,  P., Creswell,  C., Heiervang, E. R., Herren., Hogendoorn, S. M., Hudson, J.L., Krause, K., Lyneham, H.J., McKinnon, A., Morris, T., Nauta, M. H., Rapee, R. M.,  Rey, Y., Schneider, S., Schneider, S. C., Silverman, W. K., Smith, P., Thastum, M., Thirlwall, K., Waite, P.,  Wergeland, G., Eley, T. C. (2016). Non-replication of the association between 5HTTLPR and response to psychological therapy for child anxiety disorders. British Journal of Psychiatry, 208, 182-188. doi:10.1192/bjp.bp.114.154997.  
  16. Haworth, C. M. A., Carter, K., Eley, T. C., & Plomin, R. (2015)Understanding the genetic and environmental specificity and overlap between wellbeing and internalising symptoms in adolescence.Developmental Science doi: 10.1111/desc.12376
  17. Wong, C.C., Parsons, M. J., Lester, K. J., Burrage, J., Eley, T. C., Mill, J., Dempster, E. L. and Gregory, A. M. (2015) . Epigenome-wide DNA methylation analysis of monozygotic twins discordant for diurnal preference. Twin Research and Human Genetics, 18, 662-669. doi: 10.1017/thg.2015.78
  18. Waszczuk, M. A., Brown, H. M., Eley, T. C., & Lester, K. J. (2015). Attentional control theory in childhood: enhanced attentional capture by non-emotional and emotional distractors in anxiety and depression. PLoS ONE 10(11): e0141535. doi:10.1371/journal.pone.0141535.
  19. Roberts, S., Keers, R., Lester, K. J., Coleman, J. R. I., Breen, G., Arendt, K., Blatter-Meunier, J.,  Cooper, P., Creswell, C., Fjermestad, K., Havik, O. E., Herren, C., Hogendoorn, S. M., Hudson, J. L., Krause, K., Lyneham, H. J., Morris, T., Nauta, M., Rapee, R. M., Rey, Y., Schneider, S., Schneider, S. C., Silverman, W. K., Thastum, M., Thirlwall, K., Waite, P., Eley, T. C.* & Wong, C. C. Y.* (2015) HPA axis related genes and response to psychological therapies: genetics and epigenetics. Depression and Anxiety. doi:10.1002/da.22430
  20. McAdams, T. A.,Rijsdijk, F. V., Neiderhiser, J. M., Narusyte, J., Shaw, D. S., Natsuaki, M., Spotts, E. L., Ganiban, J. M., Reiss, D., Leve, L. D., Lichtenstein, P., & Eley, T. C. (2015). The Relationship between Parental Depressive Symptoms and Offspring Psychopathology: Evidence from a Children-of-Twins Study and an Adoption Study. Psychological Medicine, 45(12), 2583-94.  doi: 10.1017/S0033291715000501
  21. Waszczuk, M. A., Zavos, H. M. S., Antonova, E., Haworth, C. M. A., Plomin, R., & Eley, T. C. (2015). A multivariate twin study of trait mindfulness, depressive symptoms and anxiety sensitivity. Depression and Anxiety,32 (4).  254-261. doi: 10.1002/da.22326
  22. Eley, T. C.*, McAdams, T. A.*, Rijsdijk, F. V., Lichtenstein, P., Narusyte, J., Reiss, D., Spotts, E., Ganiban, J., Neiderheiser, J. M. (2015). The intergenerational transmission of anxiety: a children-of-twins study. American Journal of Psychiatry, 172(7), 630-637. doi: 10.1176/appi.ajp
  23. Hudson, J. L., Keers, R., Roberts, S., Coleman, J. R. I., Breen, G., Arendt, K., Bögels, S., Cooper, P., Creswell, C., Hartman, C., Heiervang, E. R., Hötzel, K., In-Albon, T., Lavallee, K., Lyneham, H. J., Marin, C.E, McKinnon, A., Meiser-Stedman, Morris, T., Nauta, M. H., Rapee, R. M.,  Rey, Y., Schneider, S., Schneider, S. C., Silverman, W. K., Thastum, M., Thirlwall, K., Waite, P., Wergeland, G., Lester, K. J., Eley, T. C. (2015). Clinical Predictors of Response to Cognitive-Behavioral Therapy in Pediatric Anxiety Disorders: The Genes for Treatment (GxT) Study. Journal of the American Academy of Child and Adolescent Psychiatry, 54(6), 454-463. doi: 10.1016/j.jaac.2015.03.018
  24. Silventoinen, K., Jelenkovic, A., Sund, R., Honda, C., Aaltonen, S., Yokoyama, Y., Tarnoki, A. D., Tarnoki, D. L., Ning, F., Ji, F., Pang, Z., Ordoñana, J. R., Sánchez-Romera, J. F., Colodro-Conde, L., Burt, S. A., Klump, K. L., Medland, S. E., Montgomery, G. W., Kandler, C., McAdams, T. A., Eley, T. C., Gregory, A. M., Saudino, K. J., Dubois, L., Boivin, M., Haworth, C. M. A., Plomin, R., Öncel, S. Y., Aliev, F., Stazi, M. A., Fagnani, C., D’Ippolito, C., Craig, J. M., Saffery, R., Siribaddana, S. H., Hotopf, M., Sumathipala, A., Spector, T., Mangino, M., Lachance, G., Gatz, M., Butler, D. A., Bayasgalan, G., Narandalai, D., Freitas, D. L., Maia, J. A., Harden, K. P., Tucker-Drob, E. M., Christensen, K., Skytthe, A., Kyvik, K. O., Hong, C., Chong, Y., Derom, C. A., Vlietinck, R. F., Loos, R. J. F., Cozen, W., Hwang, A. E., Mack, T. M., He, M., Ding, X., Chang, B., Silberg, J. L., Eaves, L. J., Maes, H. H., Cutler, T. L., Hopper, J. L., Aujard, K., Magnusson, P. K. E., Pedersen, N. L., Aslan, A. K. D., Song, Y., Yang, S., Lee, K., Baker, L. A., Tuvblad, C., Bjerregaard-Andersen, M., Beck-Nielsen, H., Sodemann, M., Heikkilä, K., Tan, Q., Zhang, D., Swan, G. E., Krasnow, R., Jang, K. L., Knafo-Noam, A., Mankuta, D., Abramson, L., Lichtenstein, P., Krueger, R. F., McGue, M., Pahlen, S., Tynelius, P., Duncan, G. E., Buchwald, D., Corley, R. P., Huibregtse, B. M., Nelson, T. L., Whitfield, K. E., Franz, C. E., Kremen, W. S., Lyons, M. J., Ooki, S., Brandt, I., Nilsen, T. S., Inui, F., Watanabe, M., Bartels, M., van Beijsterveldt, T. C. E. M., Wardle, J., Llewellyn, C. H., Fisher, A., Rebato, E., Martin, N. G., Iwatani, Y., Hayakawa, K., Rasmussen, F., Sung, J., Harris, J. R., Willemsen, G., Busjahn, A., Goldberg, J. H., Boomsma, D. I., Hur, Y., Sørensen, T. I. A. and Kaprio, J.(2015). The CODAtwins project: The cohort description of Collaborative project of Development of Anthropometrical measures in Twins to study macro-environmental variation in genetic and environmental effects on athropometric traits. Twin Research and Human Genetics, 18, 1-13.
  25. Waszczuk, M. A., Zavos, H. M. S., Gregory, A. M., & Eley, T. C. (2015). The stability and change of etiological influences on depression, anxiety symptoms and their co-occurrence across adolescence and young adulthood. Psychological Medicine.1-15. doi: 10.1017/s0033291715001634
  26. Bolhuis, K.*, McAdams, T. A.*, Monzani, B., Gregory, A. M., Mataix-Cols, D., Stringaris, A., & Eley, T. C. (2014). Etiological overlap between obsessive-compulsive and depressive symptoms: a longitudinal twin study in adolescents and adults. Psychological Medicine, 44(7), 1439-1450. doi:10.1017/S0033291713001591
  27. Lau, J. Y. F., Belli, S. R., Gregory, A. M., & Eley, T. C. (2014). Interpersonal cognitive biases as genetic markers for paediatric depressive symptoms: Twin data from the Emotions, Cognitions, Heredity and Outcome (ECHO) study. Development and Psychopathology26(4pt2),1267-1276 doi: 10.1017/S0954579414001011
  28. Krebs, G., Waszczuk, M. A., Zavos, H. M. S., Bolton, D., & Eley, T. C. (2014). Genetic and environmental influences on obsessive-compulsive behaviour across development: A longitudinal twin study. Psychological Medicine. 45(07), 1539-1549. doi: 10.1017/S0033291714002761
  29. Michelini, G., Eley, T. C., Gregory, A. M., & McAdams, T. A. (2014). Aetiological overlap between anxiety and attention deficit hyperactivity symptom dimensions in adolescence. Journal of Child Psychology and Psychiatry. 56(4), 423-431: Doi:10.1111/jcpp.12318
  30. Roberts, S., Lester, K. J., Hudson, J. L., Rapee, R. M., Creswell, C., Cooper, P. J., Thirlwall, K. J., Coleman, J. R. I., Breen, G., Wong, C. C. Y.*, Eley, T. C.* (2014) Serotonin Tranporter Methylation and Response to Cognitive Behaviour Therapy in Children with Anxiety Disorders. Translational Psychiatry, 4, e444. doi: 10.1038/tp.2014.83
  31. Dempster, E. L., Wong, C. C. Y., Lester, K. J., Burrage, J., Gregory, A. M., Mill, J., & Eley, T. C. (2014). Genome-wide methylomic analysis of monozygotic twins discordant for adolescent depression. Biological Psychiatr,76(12), 977-983. doi:10.1016/j.biopsych.2014.04.013
  32. Waszczuk, M. A.*, Zavos, H. M. S.*, Gregory, A. M., & Eley, T. C. (2014). The phenotypic and genetic structure of depression and anxiety disorder symptoms in childhood, adolescence and young adulthood. JAMA Psychiatry, 71(8), 905. doi:10.1001/jamapsychiatry.2014.655
  33. Brown, H. M.*, Waszczuk, M. A.*, Zavos, H. M. S., Trzaskowski, M., Gregory, A. M. & Eley, T. C. (2014). Cognitive content-specificity in anxiety and depressive disorder symptoms: a twin study of cross-sectional associations with anxiety sensitivity dimensions across development. Psychological Medicine, 44(16), 3469-3480, doi:10.1017/S0033291714000828
  34. Parsons, M. J., Lester, K. J., Barclay, N. L., Archer, S. N., Nolan, P. M., Eley, T. C., & Gregory, A. M. (2014). Polymorphisms in the circadian expressed genes PER3 and ARNTL2 are associated with diurnal preference and GNb3 with sleep measures. Journal of Sleep Research, 23(5) 595-604. doi:10.1111/jsr.12144
  35. McAdams, T. A., Neiderhiser, J. M., Rijsdijk, F. V., Narusyte, J., Lichtenstein, P., & Eley, T. C. (2014). Accounting for genetic and environmental familial confounds in associations between parent and child characteristics: A systematic review of children-of-twins studies. Psychological Bulletin, 140(4), 1138-1173. doi:10.1037/a0036416
  36. Brown, H. M., Eley, T. C., Broeren, S., MacLeod, C., Rinck, M., Hadwin, J., & Lester, K. J. (2014). Psychometric properties of reaction time based experimental paradigms measuring anxiety related information-processing biases in children. Journal of Anxiety disorders, 28(1), 97-107. doi:10.1016/j.janxdis.2013.11.004
  37. Scherff, A., Taylor, M., Eley, T. C., Happé, F., Charman, T., Ronald, A. (2013). What Causes Internalising Traits and Autistic Traits to Co-occur in Adolescence? A Community-Based Twin Study. Journal of Abnormal Child Psychology. 1-10. doi:10.1007/s10802-013-9796-y
  38. Barclay, N. L., Eley, T.C., Parsons, M. J., Willis, T. A., Gregory, A. M. (2013). Monozygotic Twin Differences in Non-Shared Environmental Factors Associated with Chronotype. Journal of Biological Rhythms, 28, 51-61. doi:10.1177/0748730412468698
  39. Brown, H. M., McAdams, T. C., Lester, K. J., Goodman, R., Clark, D. M., & Eley, T. C. (2013). Attentional threat avoidance and familial risk are independently associated with childhood anxiety disorders. Journal of Child Psychology and Psychiatry, 54, 678-685. doi:10.1111/jcpp.12024
  40. Hudson, L. J., Lester, K. J., Lewis, C. M., Tropeano, M., Creswell, C., Collier, D. A., Cooper, P., Lyneham, H. J., Morris, T., Rapee, R. M., Roberts, S., Donald, J., & Eley, T. C. (2013). Predicting outcomes following cognitive behaviour therapy in child anxiety disorders: the influence of genetic, demographic and clinical information. Journal of Child Psychology and Psychiatry, 54(10), 1086-1094.  doi:10.1111/jcpp.12092.
  41. McAdams, T. A., Gregory, A. M., Eley, T. C. (2013). Genes of Experience: Explaining the Heritability of Putative Environmental Variables through Their Association with Behavioural and Emotional Traits. Behavior Genetics. doi: 10.1007/s10519-013-9591-0
  42. McAdams, T. A., Gregory, A. M., Rowe, R., Zavos, H. M. S., Barclay, N. L., Lau, J. Y. F., Maughan, B., & Eley, T. C. (2013). The Genesis 12–19 (G1219) Study: A Twin and Sibling Study of Gene–Environment Interplay and Adolescent Development in the UK. Twin Research and Human Genetics, 16(1), 134-143. doi:10.1017/thg.2012.83.
  43. Parsons M. J., Lester K. J., Barclay N. L., Nolan P. M., Eley T.C., Gregory A. M. (2013). Replication of genome-wide association studies (GWAS) loci for sleep in the British G1219 cohort.  American Journal of Medical Genetics Park B, 162B: 431-438. doi:10.1002/ajmg.b.32106
  44. Richard Rowe, R., Maughan, B., Gregory, A. M., & Eley, T. C. (2013). The development of risky attitudes from pre-driving to fully-qualified driving. Injury Prevention. doi:10.1136/injuryprev-2012-040551
  45. Trzaskowski, M., Eley, T.C., Davis, O. S. P., Docherty, S. J., Hanscombe, K. B., Meaburn, E. L., Haworth, M. A., Price, T., Plomin, R. (2013). First Genome-Wide Association Study on Anxiety-Related Behaviours in Childhood. Plos ONE, 8(4), e58676. doi:10.1371/journal.pone.0058676
  46. Waszczuk, M. A., Zavos, H. M. S., Eley, T. C. (2013). Genetic and environmental influences on relationship between anxiety sensitivity and anxiety subscales in children. Journal of Anxiety Disorders, 27, 475–484. doi: 10.1016/j.janxdis.2013.05.008
  47. Wilkinson, P., Trzaskowski, M., Haworth, C. M., & Eley, T. C. (2013). The Role of Gene-Environment Correlations and Interactions in Middle Childhood Depressive Symptoms. Development and Psychopathology, 25(1), 93-104. doi: 10.1017/S0954579412000922
  48. Barclay, N. L., Eley, T.C., Buysse, D.J., Maughan, B., & Gregory, A.M. (2012). Nonshared environmental influences on sleep quality: A study of monozygotic twin differences. Behavior Genetics, 42, 234-244. doi: 10.1007/s10519-011-9510-1
  49. Brown, H. M., Trzaskowski, M., Zavos, H. M. S., Rijsdijk, F. V., Gregory, A. M. and Eley, T. C. (2012). Phenotypic and genetic structure of anxiety sensitivity in adolescence and early adulthood. Journal of Anxiety Disorders, 26, 680-688. doi: 10.1016/j.janxdis.2012.05.001
  50. Eley, T.C., Hudson, J.L., Creswell, C., Tropeano, M., Lester, K.J., Cooper, P., Farmer, A., Lewis, C.M., Lyneham, H.J., Rapee, R.M., Uher, R., Zavos, H.M.S., & Collier, D.A. (2012). Therapygenetics: The 5HTTLPR and response to psychological therapy. Molecular Psychiatry, 17, 236-237. Recipient of a Macquarie University Research Excellence Award, 2011. A spotlight was written on this paper: Beevers & McGeary (2011). "Therapygenetics: moving towards personalized psychotherapy treatment." Trends in cognitive sciences, 16, 11-12. doi: 10.1038/mp.2011.132.
  51. Lau, J. F. Y., Belli, S., Gregory, A. M., Napolitano, M. & Eley, T. C. (2012). The role of children’s negative attributions on depressive symptoms: An inherited characteristic or a product of the early environment? Developmental Science, 15, 569-578.   doi: 10.1111/j.1467-7687.2012.01152.x.
  52. Lau, J. F. Y., Hilbert, K., Goodman, R., Gregory, A.M., Pine, D.S., Viding, E.M. & Eley, T.C. (2012). 'Unnatural' fears and childhood anxiety: Investigating the genetic and environmental bases of biases in threat recognition and avoidance. Biology of Mood & Anxiety Disorders, 2(1), 1-17.
  53. Lester, K.J., Hudson, J.L., Tropeano, M., Creswell, C., Collier, D.A., Farmer, A., Lyneham, H.J., Rapee, R.M., Eley, T.C. (2012). Neurotrophic gene polymorphisms and response to psychological therapy. Translational Psychiatry, 2, e108, doi:10.1038/tp.2012.33.
  54. 44.      McAdams, T., Rowe, R., Rijsdijk, F., Maughan, B., & Eley, T.C. (2012). The covariation of antisocial behaviour and substance use in adolescence: A behavioural genetic perspective. Journal of Research on Adolescence, 22, 100-112. doi:10.1111/j.1532-7795.2011.00758.x
  55. Scaini, S., Ogliari, A., Eley, T.C., Zavos, H.M.S., Battaglia, M. (2012). Genetic and environmental contributions to separation anxiety: A meta-analytic approach to twin data. Depression and Anxiety,  29(9), 754–761. doi: 10.1002/da.21941
  56. Stringaris, A., Zavos, H. M. S., Leibenluft, E., Maughan, B., & Eley, T. C. (2012). Adolescent irritability: phenotypic associations and genetic links with depressed mood. American Journal of Psychiatry, 169, 47-54. doi: 10.1176/appi.ajp.2011.10101549
  57. Trzaskowski, M., Zavos, H.M.S., Haworth, C.M.A., Plomin, R., & Eley, T.C. (2012). Stable Genetic Influence on Anxiety-Related Behaviours Across Middle Childhood, Journal of Abnormal Child Psychology, 40, 85-94. doi: 10.1007/s10802-011-9545-z
  58. Zavos, H. M. S., Gregory, A. M., & Eley, T. C. (2012). Longitudinal genetic analysis of anxiety sensitivity. Developmental Psychology, 48, 204-212. doi: 10.1037/a0024996
  59. Zavos, H.M.S., Rijsdijk, F.V.R., Eley, T.C. (2012). A longitudinal genetically informative study of associations between anxiety sensitivity, anxiety and depression. Behavior Genetics, 42, 592-602 . doi:10.1007/s10519-012-9535-0
  60. Zavos, H. M. S., Wong, C. C. Y., Barclay, N. L., Keers, R., Mill, J., Rijsdijk, F. V., Gregory, A. M.,  Eley, T. C. (2012).  Anxiety sensitivity in adolescence and young adulthood: the role of stressful life events, 5HTTLPR and their interaction. Depression and anxiety, 29, 400-408. doi: 10.1002/da.21921
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