I am Professor of Developmental Behavioural Genetics at the Institute of Psychiatry, Psychology & Neuroscience, King’s College London. I direct the Emotional Development, Intervention and Treatment (EDIT) lab, and my work focuses on the interplay between genetic and environmental factors in the development and treatment of anxiety and depression.
For my undergraduate degree I studied Social and Political Sciences, with a focus on psychology, at Trinity College Cambridge. I undertook my PhD at the Institute of Child Health, University College London, where I studied the role of genetic and environmental influences on depression and anxiety in young people. After two MRC research fellowships, I became a member of academic staff at the Institute of Psychiatry, Psychology and Neuroscience and was promoted to Professor in 2013.
My work is highly interdisciplinary using both the twin design and molecular genetic approaches, and drawing on cognitive, clinical and developmental psychology. I have written over 140 empirical papers and received numerous awards including the Spearman Medal from the British Psychological Society, the Lilly-Molecular Psychiatry Award, and most recently the James Shields Lifetime Achievement Award from the International Society for Twin Studies. I am one of the Chairs of the Psychiatric Genomics Consortium Anxiety Group.
I am really passionate about enabling early career researchers and was Chair of the Research and Innovation Committee for over 5 years, developing and leading numerous initiatives aimed at supporting this group. I am very keen to see greater diversity in those conducting, and taking part, in scientific research.
You can watch various videos about my work below:
Inaugural lecture (Autumn 2013) here, in which I gave an overview of the work I undertook from my PhD in the 1990s until 2013 when I became a professor.
Therapygenetics lecture (Spring 2017) here, as part of the Stockholm Psychiatry lecture series.
This lecture is a brief update of the work of the Psychiatric Genetics Consortium Anxiety group (Spring 2020).
I am particularly interested in finding ways in which genetic approaches can inform psychological practise as well as theory. Using molecular genetics, I am exploring the role of specific genetic markers in the development of anxiety and depression, and as predictors of psychological therapies response for these conditions. With my close colleague Prof Gerome Breen, head of the NIHR Maudsley BioResource centre, I am leading the new Genetics Links to Anxiety and Depression (GLAD) Study. You can watch us describing the purpose of this study here, and can watch an animation about the study here. I am particularly excited about this area of work as it has the potential to be useful in making clinical decisions.
I am also keen to understand why anxiety and depression tend to run in families, and whether this is due to sharing home life or whether it is due to sharing genes. I am the Director of the Twins Early Development Study (TEDS), the largest longitudinal twin birth cohort in the UK. As our twins reach their mid-twenties we are particularly excited about recruiting the next generation into the Children of TEDS (CoTEDS) Study.
Expertise and Public Engagement:
EDITlab runs a blog. The GLAD Study participants are recruited via the media and social media so we have written and had lots of articles written about us, as well as featuring on TV, traditional media etc. We also worked closely with many charities (e.g. MIND) and with the British Psychological Society and Royal College of Psychiatrists all of whom supported and promoted the study.
I have written blogs for Mental Elf and have spoken at Pint of Science twice.
- 2021 Fellow of the Academy of Medical Sciences
- 2019 KCL University Research Project of the year (GLAD Study)
- 2017 James Shields Lifetime Achievement Award from the International Society for Twin Studies
- 2017 KCL Graduate School IoPPN Supervisory Excellence Award
- 2004 Lilly-Molecular Psychiatry Award
- 2002 British Psychological Society Spearman Medal
- SGDP Education lead
- Assessment Sub-Board Chair for SGDP DEV-PP Masters programme
- Teaching on genetics of anxiety, depression and treatment response.
- Grant writing training.
McGregor, T., Purves, K., Barry, T., Constantinou, E., Craske, M. G., Breen, G., Young, K. & Grant, T. E., 9 Aug 2022, (Accepted/In press) In: Behaviour Research Methods. Research output: Contribution to journal › Article › peer-review
Leigh, E., Rimfeld, K., Bowes, L., Clark, D. M., Eley, T. C. & Krebs, G., 15 Jun 2022, In: Journal of affective disorders. 307, p. 199-205 7 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.jad.2022.03.073
Buckman, J. E. J., Saunders, R., Stott, J., Cohen, Z. D., Arundell, L. L., Eley, T. C., Hollon, S. D., Kendrick, T., Ambler, G., Watkins, E., Gilbody, S., Kessler, D., Wiles, N., Richards, D., Brabyn, S., Littlewood, E., Derubeis, R. J., Lewis, G. & Pilling, S., May 2022, In: JAMA Psychiatry. 79, 5, p. 406-416 11 p. Research output: Contribution to journal › Review article › peer-review. DOIs: https://doi.org/10.1001/jamapsychiatry.2022.0100
Wootton, R. E., Riglin, L., Blakey, R., Agnew-blais, J. C., Caye, A., Cadman, T., Havdahl, A., Gonçalves, H., Menezes, A., Wehrmeister, F., Rimfeld, K., Smith, G. D., Eley, T., Rohde, L. A., Arseneault, L., Moffitt, T., Stergiakouli, E., Thapar, A. & Tilling, K., Jun 2022, In: International Journal of Epidemiology. 51, 3, p. 919-930 12 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1093/ije/dyac049
Peel, A. J., Purves, K. L., Baldwin, J. R., Breen, G., Coleman, J. R. I., Pingault, J. B., Skelton, M., Ter Kuile, A. R., Danese, A. & Eley, T. C., 2 Feb 2022, (E-pub ahead of print) In: British Journal of Psychiatry. 8 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1192/bjp.2021.207
Buckman, J. E. J., Saunders, R., Arundell, L-L., Oshinowo, I. D., Cohen, Z. D., O'Driscoll, C., Barnett, P., Stott, J., Ambler, G., Gilbody, S., Hollon, S. D., Kendrick, T., Watkins, E., Eley, T., Skelton, M., Wiles, N., Kessler, D., DeRubeis, R. J., Lewis, G. & Pilling, S., 15 Feb 2022, In: Journal of Affective Disorders. 299, p. 298-308 11 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.jad.2021.12.030
Rimfeld, K., Malanchini, M., Packer, A., Gidziela, A., Allegrini, A., Ayorech, Z., Smith-Woolley, E., McMillan, A., Ogden, R., Dale, P. S., Eley, T. & Plomin, R., 9 Nov 2021, (Accepted/In press) In: Journal of Child Psychology and Psychiatry. Research output: Contribution to journal › Article › peer-review
Davies, M. R., Buckman, J. E. J., Adey, B. N., Armour, C., Bradley, J. R., Curzons, S. C. B., Davies, H. L., Davis, K. A. S., Goldsmith, K. A., Hirsch, C. R., Hotopf, M., Hübel, C., Jones, I. R., Kalsi, G., Krebs, G., Lin, Y., Marsh, I., McAtarsney-Kovacs, M., McIntosh, A. M., Mundy, J. & 12 others, , Jan 2022, In: Journal of Anxiety Disorders. 85, 102491. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.janxdis.2021.102491
Malanchini, M., Rimfeld, K., Gidziela, A., Cheesman, R., Allegrini, A. G., Shakeshaft, N., Schofield, K., Packer, A., Ogden, R., McMillan, A., Ritchie, S. J., Dale, P. S., Eley, T. C., von Stumm, S. & Plomin, R., 1 Oct 2021, (E-pub ahead of print) In: Molecular Psychiatry. 26, 12 Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41380-021-01300-0
Gidziela, A., Rimfeld, K., Malanchini, M., Allegrini, A. G., McMillan, A., Selzam, S., Ronald, A., Viding, E., von Stumm, S., Eley, T. C. & Plomin, R., 6 Sep 2021, (E-pub ahead of print) In: Journal of Child Psychology and Psychiatry and Allied Disciplines. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1111/jcpp.13519