Chronic urban particulate matter exposure aggravates myocardial infarction by sequential impairment of lung redox metabolism, inflammation, and cardiac mitochondrial function

Speaker: Professor Timoteo Marchini, School of Pharmacy and Biochemistry, University of Buenos Aries, Argentina

Description: The environmental particulate matter exposure is associated with cardiovascular disease onset and progression, leading to increased morbidity and mortality rates mainly from myocardial infarction. Herein, we will provide mechanistic insights on this observation, with a special focus on lung impaired redox metabolism, local and systemic inflammation, and cardiac mitochondrial function.