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From mice to men in modelling hypertrophic cardiomyopathy
Speaker: Dr Christopher Toepfer, Harvard Medical School
Hypertrophic cardiomyopathy (HCM), the thickening of the myocardium afflicts 1 in 200 individuals. We define novel mechanisms that drive known pathogenic HCM in MYBPC3 and MYH7 and develop assays to test variants of unknown significance in HCM, using CRISPR Cas-9 genome engineering and iPSC-CM technologies
Event details
G8, Ground floor, New Hunt’s House, Guy’s CampusNew Hunt’s House
Great Maze Pond, London, SE1 9RT