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Speaker Dr Jeremy Carlton, Wellcome Trust Senior Research Fellow, School of Cancer and Pharmaceutical Sciences, KCL

Title FTD- and ALS-causing mutations in CHMP2B and ANXA11 impact a common pathway of membrane repair

Host Elisabetta Brunello 


Abstract ESCRT-III is an ancient membrane remodelling machinery that has been co-opted through evolution to perform a variety of cellular membrane remodelling processes. Here we explore pathogenic FTD-causing mutations in the ESCRT-III subunit CHMP2B and use them to understand how cells respond to, and repair, damaged membranes. I’ll also give an overview of other projects in the lab. 

Event details

New Hunt’s House
Great Maze Pond, London, SE1 9RT