Join us to celebrate a special milestone for our new professors and hear about their inspiring career journeys. Doors for this event will open at 16.45, with the lectures to commence at 17.00. A drinks reception will be held immediately after the lecture at 18:00.

Please note that registration will close at midnight the Sunday before the lecture.

Professor James Arnold

Back to the Future: 8,324 Days Exploring Immunology and Cancer

Abstract

Professor James Arnold will reflect on his research journey, from studying innate immune molecules in the blood to uncovering cellular immune response networks in cancer. Along the way, he will highlight the key figures and mentors who have inspired him, and share how these experiences fuelled his passion for discovery science and his drive to translate those discoveries towards clinical impact.

Biography

James began his scientific career at the University of Oxford in 2002, studying the complement system with Dr. Bob Sim, focusing on mannan-binding lectin and its binding partners. In 2007, he joined Professor Douglas Fearon at the CRUK Cambridge Research Institute to investigate tumour immunology and the immunosuppressive role of cancer-associated fibroblasts.

In 2010, James was awarded a Cancer Research Institute Fellowship to study macrophage subsets. James joined King’s College London in 2012, where he established the Tumour Immunology group with support from a European Research Council Start-Up Grant. His team’s research has contributed to advancing our understanding of tumour-associated macrophages, the role of the enzyme heme oxygenase-1, and developed novel CAR T-cell therapy approaches for solid tumours. James is currently supported by a Cancer Research UK Programme Foundation Award.

---

Professor Jeremy Carlton

Organisation and reorganisation of the cell’s internal architecture

Abstract

Cells are the fundamental unit of life, and their behaviour, both normal and malign, underlies all aspects of health and disease. Inside each cell are cytoskeletal elements that give cells form and allow their movement, a nucleus that encloses the genome, and a variety of intracellular membrane-bound organelles that compartmentalise the biochemical functions necessary for life. Proliferating cells are challenged by the need to dismantle and reconstruct this architecture during each round of division, migrating cells must deal with physical stresses, and all cells must ensure that the membrane boundaries that allow this compartmentalisation are maintained. In this inaugural lecture, I will reflect on our efforts to understand this dynamic complexity and will reveal how cells remodel and reorganise their internal architecture when negotiating these challenges. 

Biography

 Jeremy Carlton is a Wellcome Trust Senior Research Fellow, Professor of Molecular Cell Biology and Head of the Department of Cancer Biology in the School of Cancer & Pharmaceutical Sciences at King’s College London. After an undergraduate degree in Natural Sciences from the University of Cambridge, he completed a PhD in Biochemistry at the University of Bristol. He moved to the Department of Infectious Diseases at King’s as a Beit Memorial Research Fellow and later established his lab in the Division of Cancer Studies at King’s with a Wellcome Trust Research Career Development Fellowship.

He is an EMBO Young Investigator, Biochemical Society Early Career and British Society for Cell Biology Hooke Medal winner. His lab study how cellular membranes and organelles are remodelled during cell division, during cell migration and how cellular membranes are repaired when damaged.