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The influence of antibody subclass on human B cell development
Speaker: Louisa James
Host: Dr Alexandra Santos
The James group aims to understand the role of antibody in B cell development and in particular the regulation and maintenance of B cell memory.
The ability of B cells to generate antibody and provide immune memory is one of the cornerstones of immunology. Humans make nine different antibody subclasses with effector functions that differ according to the type of antigen and route of exposure. We are combining molecular approaches such as single cell RNAseq and high-throughput antibody repertoire sequencing to examine how antibody subclass influences the induction, expansion and maintenance of human B cells.
Event details
Gowland Hopkins Lecture Theatre, Hodgkin BuildingGuy’s Campus
Great Maze Pond, London SE1 1UL