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Understanding Cortical Development and Disease: From Embryos to Brain Organoids

Speaker: Dr Paola Arlotta

Paola Arlotta, Ph.D., is the Chair and Golub Family Professor of Harvard’s Department of Stem Cell and Regenerative Biology. She is also Associate Member of the Stanley Center for Psychiatric Research at the Broad Institute.

Collectively, the Arlotta lab research program explores the interface between development and engineering of the neocortex, to gain fundamental understanding of both the principles that govern normal cortical development and of previously-inaccessible mechanisms of human neurodevelopmental disease. The lab is working to understand and model complex human cortical pathology, focusing on the development of new high-throughput in vitro models of human cortical development and neurodevelopmental disease using 3D cerebral organoids.

Dr. Arlotta received her M.S. in biochemistry from the University of Trieste, Italy, and her Ph.D. in molecular biology from the University of Portsmouth in the UK. She subsequently completed her postdoctoral training in neuroscience at Harvard Medical School.

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