Members of the SGU work on a wide range of projects, broadly centred on the genetics of complex traits. We have well-established and productive collaborations with molecular and clinical research groups with members based at the SGDP working on projects including statistical methods for the analysis of complex multivariate psychiatric phenotypes, and genome-wide studies of single phenotypes such as depression. Members based at the GMM work on projects including genome-wide studies of psoriasis and inflammatory bowel disease, and on the analysis of phenotypes related to transplant outcome thanks to a close collaboration with the MRC Centre for Transplantation. At both the SGDP and GMM, there is a growing interest in the combined analysis of genetic data with other types of “omic” data.
The very real questions arising from these projects, in the context of the constantly changing landscape of molecular data generation technologies, are what motivate our research into new statistical developments and data analysis approaches.
Click on the Statistical Genetics Unit homepage for further details.