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09 April 2020

Scientists launch study to assess how stress hormone reacts to COVID-19

King’s College London is working with scientists from University of Nottingham on a major new study to understand how the COVID-19 pandemic is affecting the physical and emotional health of the nation.

Scientists launch study to assess how stress hormone reacts to COVID-19

The COVID-19 pandemic has resulted in unprecedented disruption to the fabric of society, the health service and economy. Social distancing measures have been introduced to slow the spread of the virus and this new and constrained way of living, as well as the other challenges resulting from the pandemic, are already likely to be affecting emotional and physical well-being.

The COVID-19 Stress and Health Study, will examine these effects by taking repeated assessments of emotional well-being in a sample of the population using questionnaires and by collecting samples of hair which contains stress hormones. The UK-wide study is being carried out with the support of the stress hormone testing company MyFertile.

Kavita Vedhara, Professor of Health Psychology, at the University of Nottingham, who is leading the study said: ‘We have worked in the area of stress and health for 30 years now, and one of the key things we’ve learnt is that when we experience stressful situations for protracted periods of time, such as during this pandemic, it can have real implications for our health and wellbeing. So, we are seeking to understand, whether and how the pandemic is affecting us emotionally and physically.’

Our study will help assess how any stress experienced during this period of uncertainty could affect health in the future and the impact on the immune system which is key to defending against the virus.

Trudie Chalder, Professor of Cognitive Behavioural Psychotherapy at King’s College London

Participants will be asked to complete a short online survey on three occasions; on entry into the study, 12 weeks later, and potentially again after a change in social distancing has been introduced. Participants will also be asked to provide a small sample of hair for later measurement of the stress hormone cortisol.

Professor Vedhara explains: ‘Cortisol is really important in regulating the normal functioning of our body, in particular its importance in regulating how our immune system works, so you can see how levels of this hormone might be really important in determining our future physical health.  The reason we are measuring it in hair is twofold - firstly because it will be really simple and easy for people to do at home, but also – because it is an incredibly reliable way of looking at long term measures of this hormone. Providing these hair samples will allow us to explore whether any stress you experience today and in the coming weeks could affect your health in the future. We will be seeking funding to measure cortisol in these samples at the end of the study.’

Recruitment to the first phase of the study is only open for the month of April so that the team can capture the early effects of the pandemic. Please visit the study website for more information on how you can take part.