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10 October 2016

A new study led by researchers from King’s College London, the University of Edinburgh and Imperial College London, will investigate whether a drug called methylphenidate (MPH) reduces symptoms of attention-deficit/hyperactivity disorder (ADHD) and antisocial behaviour in young male prisoners with the disorder.

A new study led by researchers from King’s College London, the University of Edinburgh and Imperial College London, will investigate whether a drug called methylphenidate (MPH) reduces symptoms of attention-deficit/hyperactivity disorder (ADHD) and antisocial behaviour in young male prisoners with the disorder.

Around 30 per cent of young prisoners are thought to have ADHD, compared to three or four per cent of young people in the general population. Although MPH is the first line of treatment for ADHD in the UK, it has yet to be investigated as a treatment for young prisoners.

MPH works by increasing dopamine levels in the brain. This boosts brain activity in areas related to attention and behaviour regulation and can have a huge impact on improved self-control of behaviour and function in education and work.

ADHD is a developmental disorder marked by severe and impairing levels of inattention, hyperactivity and impulsivity. These are all symptoms that overlap with and could be explained by other mental health disorders seen in prisoners, which is one reason why the disorder currently goes undiagnosed and untreated in prisons.

The £1.3 million study is an eight-week clinical trial of 200 young adults, aged 16 to 25, at three young offender institutes and prisons, including Polmont in Falkirk, Isis in London and Rochester in Kent.

Prisoners will be given MPH once a day for eight weeks and ADHD symptoms will be measured through clinician ratings and interviews. The study will also measure a range of other factors, including irritable and angry outbursts, antisocial behaviour, attitudes towards violence and positive engagement with education and rehabilitation activities.

‘ADHD in prisoners tends to go undiagnosed and untreated, perhaps due to overlapping symptoms with other mental health issues, such as personality disorder, anxiety, post-traumatic stress and substance abuse. As a result the effects of treating ADHD in prisoners remain unclear.

Professor Philip Asherson from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London

Professor Asherson added: ‘Following a course of methylphenidate, we’re hoping to see a reduction in ADHD symptoms and antisocial behaviour, as well as increased positive engagement with educational and offender rehabilitation programmes.

‘If the treatment is effective in a prison setting, this will pose bigger questions around what happens to prisoners when they are released. Does it lead to better functioning in society and a drop in subsequent criminal offending? These are the issues we will seek to examine in future research.’

Read the full story on the King’s website.

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