Show/hide main menu


News Highlights

Peanut in house dust linked to allergy and eczema in infancy

Posted on 19/11/2014

A new study led by researchers at King’s College London in collaboration with the US Consortium of Food Allergy Research and the University of Dundee has found a strong link between environmental exposure to peanut protein during infancy (measured in household dust) and an allergic response to peanuts in children who have eczema early in life.

Around two per cent of school children in the UK and the US are allergic to peanuts. Severe eczema in early infancy has been linked to food allergies, particularly peanut allergy. 

The study, published in the Journal of Allergy and Clinical Immunology, looked at the amount of peanut protein infants aged 3-15 months were exposed to in house dust, by vacuuming dust from the living room and measuring peanut in the dust. The study was conducted in 359 children who had a high risk of developing peanut allergy because they were allergic to cow’s milk or egg or had moderate to severe eczema and had tested positive for an allergy to cow’s milk or egg. 

The study found that exposure to peanut in dust early in life doubled the risk of peanut allergy. In children with a history of eczema, the risk of peanut allergy increased further. 

Dr Helen A Brough, first author from the Department of Paediatric Allergy, King’s College London, said: “This study adds to the growing body of evidence that exposure to peanut via a damaged skin barrier may increase the risk of peanut  allergy. Previous studies have shown, for example, that infants with eczema treated with creams containing peanut oil in the first six months of life had a higher risk of developing peanut allergy later in life.”

Professor Gideon Lack, senior author from the Department of Paediatric Allergy, King’s College London, said: “This is further evidence for the dual-allergen-exposure theory which suggests food allergies develop through exposure to allergens via the skin, likely through a disrupted skin barrier, whilst consumption of these food proteins early in life builds up tolerance in the body. Previous guidelines recommending that mothers should avoid peanuts during pregnancy and breastfeeding have now been withdrawn. It may be that the timing and balance of skin and oral exposure to a particular food early in life determines whether a child develops an allergy or tolerance to that food.” 

Notes to editors

For further information, please contact Jenny Gimpel, PR Manager (Health) at King’s College London on 0207 848 4334, email

‘Atopic dermatitis increases the impact of exposure to peanut antigen in dust on peanut sensitization and likely peanut allergy’ by Brough et al. is published in the Journal of Allergy and Clinical Immunology on Wednesday 19 November 2014.

The study was funded by Action Medical Research and supported by the National Institute for Health Research (NIHR) Clinical Research Facility at Guy’s & St. Thomas’ NHS Foundation Trust and the NIHR Biomedical Research Centre based at Guy’s and St Thomas’ NHS Foundation Trust and Kings College London. The CoFAR study was funded by a grant (AI66738) from the National Institutes of Health (NIH)/National Institute of Allergy and Infectious Disease (NIAID). The project was also supported by grants from the National Center for Advancing Translational Services (NCATS), a component of the National Institutes of Health (NIH) to National Jewish Health, Mount Sinai, University of Arkansas for Medical Sciences, University of North Carolina and Johns Hopkins University.  The Centre for Dermatology and Genetic Medicine at the University of Dundee is supported by the Wellcome Trust.

News Highlights:

News Highlights...RSS FeedAtom Feed

Negotiation with all extremist groups is inevitable, says Blair's ex-chief of staff

Negotiation with all extremist groups is inevitable, says Blair's ex-chief of staff

Negotiations with violent extremist groups such as Islamic State are 'inevitable', Tony Blair's former Chief of Staff Jonathan Powell said at an event at King's College London last night.Speaking at the launch of his new book: 'Talking to Terrorists', Mr Powell, who was chief negotiator in the Northern Ireland peace deal, said history has repeatedly shown that however brutal the terror tactics, face to face talks will eventually take place.
'Raising finance: Top tips from industry experts'

'Raising finance: Top tips from industry experts'

The keynote speakers, Jon Moulton, Founder and Managing Partner of Better Capital, Carlos Eduardo, Partner of Seedcamp, Julia Meyer MBE, Founder of Ariadne Capital and Nigel Verdon, Chairman and Founder of Currency Cloud, discussed their business ventures in the world of finance, offering advice and guidance to an audience of keen entrepreneurs at New Hunt's House.
Award-winning 'Strategy' an 'intellectual tour de force'

Award-winning 'Strategy' an 'intellectual tour de force'

Strategy: A History, Professor Sir Lawrence Freedman's magnum opus on the role of strategy throughout world civilization, was this week awarded the 2014 W.J.M. Mackenzie Book Prize at the Political Studies Association's annual awards in London.
Sitemap Site help Terms and conditions  Privacy policy  Accessibility  Modern slavery statement  Contact us

© 2019 King's College London | Strand | London WC2R 2LS | England | United Kingdom | Tel +44 (0)20 7836 5454