Dr Abdul Hye

Abdul is a senior research scientist with over 15 years’ experience in the field of biomarker research in neurodegenerative disorders; such as Alzheimer’s disease (AD), Parkinson’s (PD) and dementia with lewy bodies (DLB). Abdul completed his BSc in Physiology and Pharmacology (1999) and achieved a PhD in Neuroscience at King’s College London (2008).

He has extensive experience in developing single- and multiplex immunoassays along with protein separation using two-dimensional electrophoresis and mass spectrometry. He published a seminal paper in 2006 (cited over 400 times) to reveal the first set of blood markers that were related to Alzheimer’s disease, this received much attention and eventually was patented by King’s College London. Since, then he has gone on to develop a novel approach of selecting individuals based on their disease pathology based on brain imaging one of the gold standards for diagnosing AD. This has opened a different avenue of disease biomarker research. In 2014 he applied this approach on a large cohort and discovered that a combination of biomarkers could accurately predict disease association and the individuals that will convert to disease. This paper received worldwide coverage and made the front page of tabloid and broadsheet newspapers in UK. The content was also covered by all major news channels in the UK as well. Currently he is applying his expertise to other neurodegenerative disorders such PD and DLB which are very much understudied. 

Research Interests:

• Proteomics (Two-dimensional electrophoresis, SDS-PAGE, Western blot, SELDI, MALDI)
• Single & Multi-plex immunoassays (ELISA, MSD & Simoa)
• Immunoprecipitation & Immunohistochemistry