Biography
I am a clinically qualified postdoctoral researcher in innate immunity who has expertise in the complement system of host defence in infectious disease and previous experience in Toll-like receptors on macrophages in human mycobacterial infection. Since 2017 I am working as a research fellow at King’s College London in Professor Steven Sacks’ group. I have started this post by developing a PET tracer to image and quantify complement deposition in complement-mediated inflammation on solid organs. After the outbreak of the COVID19 pandemic, I have initiated a project that seeks to verify the role of the lectin complement pathway in the alveolar epithelial response to SARS-CoV-2 and whether local complement inhibition would suppress this response. There is now a lot of evidence that the complement system and in particular the lectin pathway may start the immune response at the portal of entry. Moreover, this project aims to verify the role of complement as an orchestrator of the SARS-CoV-2-induced hyperinflammatory response occurring during acute respiratory distress syndrome.
Research
Sacks Group
Examining how locally made components of the defence system influence the acceptance of foreign tissue or cell grafts
Research
Sacks Group
Examining how locally made components of the defence system influence the acceptance of foreign tissue or cell grafts