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Professor Reader is an expert in positron emission tomography (PET) image reconstruction and analysis, and one of the pioneers for a number of major advances, including: iterative list-mode 3D image reconstruction, image-space resolution modelling and fully 4D image reconstruction. His recent research has focused on MR-informed reconstruction of PET data and synergistic PET-MR modelling and reconstruction, pursuing integration of PET and MR reconstruction with machine learning. He received his BSc in Physics with Computational Physics from the University of Kent at Canterbury in 1995, his PhD in Medical Physics from the University of London in 1999. He joined the University of Manchester (then UMIST), in 1999 as a Lecturer, became a Senior Lecturer in 2005, and in 2008 he became an Associate Professor at McGill University, Canada, where he also held a Canada Research Chair in PET imaging for 6 years. In 2014 he moved to King's College London, and became a full Professor in 2015.