Brian Sutton Professor Brian Sutton Academics Supervisors Professor of Molecular Biophysics Research subject areas Biomedical and life sciences Contact details brian.sutton@kcl.ac.uk +44 (0) 20 7848 6423
Differences between human and mouse igm fc receptor (Fcμr) Kubagawa, H., Skopnik, C. M., Al‐qaisi, K., Calvert, R. A., Honjo, K., Kubagawa, Y., Teuber, R., Aliabadi, P. M., Enghard, P., Radbruch, A. & Sutton, B. J., 1 Jul 2021, In: International Journal of Molecular Sciences. 22, 13, 7024. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.3390/ijms22137024 Reviving lost binding sites: Exploring calcium binding-site transitions between human and murine CD23 Ilkow, V., Davies, A. M., Dhaliwal, B., Beavil, A., Sutton, B. & McDonnell, J., Jul 2021, In: FEBS Open Bio. 11, 7, p. 1827-1840 14 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1002/2211-5463.13214 Identification of Amino Acid Residues in Human IgM Fc Receptor (FcµR) Critical for IgM Binding Skopnik, C. M., Al-Qaisi, K., Calvert, R. A., Enghard, P., Radbruch, A., Sutton, B. J. & Kubagawa, H., 27 Jan 2021, In: Frontiers in Immunology. 11, 618327. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.3389/fimmu.2020.618327 IgE to epitopes of Ara h 2 enhance the diagnostic accuracy of Ara h 2-specific IgE Santos, A., Barbosa-Morais, N. L., Hurlburt, B. K., Ramaswamy, S., Hemmings, O., Kwok, M., O’Rourke, C., Bahnson, H. T., Cheng, H., James, L., Gould, H., Sutton, B. J., Maleki, S. J. & Lack, G., 1 Sep 2020, In: Allergy. 75, 9, p. 2309-2318 10 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1111/all.14301 Engineering the Fab fragment of the anti-IgE omalizumab to prevent Fab crystallization and permit IgE-Fc complex crystallization Mitropoulou, A., Ceska, T., Heads, J., Beavil, A., Henry, A. J., McDonnell, J., Sutton, B. & Davies, A. M., 1 Mar 2020, In: Acta Crystallographica Section F:Structural Biology Communications. 76, p. 116-129 14 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1107/S2053230X20001466 Interplay between Affinity and Valency in Effector Cell Degranulation: A Model System with Polcalcin Allergens and Human Patient–Derived IgE Antibodies Bucaite, G., Kang-Pettinger, T., Moreira, J., Gould, H. J., James, L. K., Sutton, B. & McDonnell, J. M., 1 Oct 2019, In: Journal of Immunology. 203, 7, p. 1693-1700 8 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.4049/jimmunol.1900509 Mapping of the binding site for FcμR in human IgM-Fc Nyamboya, R. A., Sutton, B. J. & Calvert, R. A., 23 Aug 2019, (E-pub ahead of print) In: BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS. 1868, 1, 140266. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.bbapap.2019.140266 IgE Antibodies: From Structure to Function and Clinical Translation Sutton, B. J., Davies, A. M., Bax, H. J. & Karagiannis, S. N., 22 Feb 2019, In: Antibodies (Basel, Switzerland). 8, 1 Research output: Contribution to journal › Review article › peer-review. DOIs: https://doi.org/10.3390/antib8010019 A mass spectrometry-based modelling workflow for accurate prediction of IgG antibody conformations in the gas phase Hansen, K., Lau, A. M. C., Giles, K., McDonnell, J. M., Struwe, WB., Sutton, B. J. & Politis, A., 21 Dec 2018, In: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 57, 52, p. 17194-17199 Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1002/anie.201812018 The structure of PghL hydrolase bound to its substrate poly-γ-glutamate Ramaswamy, S., Rasheed, M., Morelli, C. F., Calvio, C., Sutton, B. J. & Pastore, A., 2 Nov 2018, (E-pub ahead of print) In: FEBS Journal. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1111/febs.14688 View all publications