Dr Charlotte Horne

Biography

I started working at King’s in November 2018 as a postdoctoral research associate in the department of psychosis studies. I am interested in finding biomarkers of psychiatric disease focusing on schizophrenia and depression and am currently working on the MUTRIP project (Mechanisms Underlying Treatment Resistance in Psychosis). I use MRI techniques such as fMRI, structural MRI and MRS, and computational approaches such as DCM, to understand why some patients with psychosis do not adequately respond to antipsychotic medication. I am also working on integrating polygenic risk scores into our analyses as well as contributing to a clinical trial.  

Previously, I completed my MSc here at the IOPPN before doing my PhD at the University of Roehampton where I focused on the behavioural and neural mechanisms underlying the link between late chronotype (i.e. ‘night owls’) and major depression. I have a teaching qualification from the Higher Education Academy and have previously taught on undergraduate statistics workshops as well as psychology modules.  

Research Interests

•  Treatment resistance in schizophrenia 
•  Circadian rhythms in psychiatric disease (e.g. depression, schizophrenia) 
•  Neuroimaging (primarily MRI) and computational methods  

Research Groups

Cognition, Schizophrenia and Imaging lab (CSI lab)