Dr Javier Barallobre-Barreiro Research fellows Supervisors BHF Intermediate Fellow Contact details javier.barallobre-barreiro@kcl.ac.uk
Extracellular Matrix Profiling and Disease Modelling in Engineered Vascular Smooth Muscle Cell Tissues Reed, E., Fellows, A., Lu, R., Rienks, M., Schmidt, L., Yin, X., Duregotti, E., Brandt, M., Krasemann, S., Hartmann, K., Barallobre-Barreiro, J., Addison, O., Cuello, F., Hansen, A. & Mayr, M., Dec 2022, In: Matrix Biology Plus. 16, 100122. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.mbplus.2022.100122 Reduced secretion of neuronal growth regulator 1 contributes to impaired adipose-neuronal crosstalk in obesity Duregotti, E., Reumiller, C. M., Mayr, U., Hasman, M., Schmidt, L. E., Burnap, S. A., Theofilatos, K., Barallobre-Barreiro, J., Beran, A., Grandoch, M., Viviano, A., Jahangiri, M. & Mayr, M., Dec 2022, In: Nature Communications. 13, 1, 7269. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41467-022-34846-w Extracellular Matrix in Heart Failure: Role of ADAMTS5 in Proteoglycan Remodeling Barallobre-Barreiro, J., Radovits, T., Fava, M., Mayr, U., Lin, W. Y., Ermolaeva, E., Martínez-López, D., Lindberg, E. L., Duregotti, E., Daróczi, L., Hasman, M., Schmidt, L. E., Singh, B., Lu, R., Baig, F., Siedlar, A. M., Cuello, F., Catibog, N., Theofilatos, K., Shah, A. M., & 5 othersCrespo-Leiro, M. G., Doménech, N., Hübner, N., Merkely, B. & Mayr, M., 21 Dec 2021, In: Circulation. 144, 25, p. 2021-2034 14 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1161/CIRCULATIONAHA.121.055732 Paracrine signalling by cardiac calcitonin controls atrial fibrogenesis and arrhythmia Moreira, L. M., Takawale, A., Hulsurkar, M., Menassa, D. A., Antanaviciute, A., Lahiri, S. K., Mehta, N., Evans, N., Psarros, C., Robinson, P., Sparrow, A. J., Gillis, M. A., Ashley, N., Naud, P., Barallobre-Barreiro, J., Theofilatos, K., Lee, A., Norris, M., Clarke, M. V., Russell, P. K., & 16 othersCasadei, B., Bhattacharya, S., Zajac, J. D., Davey, R. A., Sirois, M., Mead, A., Simmons, A., Mayr, M., Sayeed, R., Krasopoulos, G., Redwood, C., Channon, K. M., Tardif, J. C., Wehrens, X. H. T., Nattel, S. & Reilly, S., 19 Nov 2020, In: Nature. 587, 7834, p. 460-465 6 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41586-020-2890-8 Extracellular matrix protein signature of recurrent spontaneous cervical artery dissection Mayer-Suess, L., Pechlaner, R., Barallobre-Barreiro, J., Boehme, C., Toell, T., Lynch, M., Yin, X., Willeit, J., Gizewski, E., Perco, P., Ratzinger, G., Kiechl, S., Mayr, M. & Knoflach, M., 13 Oct 2020, In: Neurology. 95, 15, p. e2047-e2055 Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1212/WNL.0000000000010710 Cathepsin A contributes to left ventricular remodeling by degrading extracellular superoxide dismutase in mice Hohl, M., Mayr, M., Lang, L., Nickel, A. G., Barallobre-Barreiro, J., Yin, X., Speer, T., Selejan, S. R., Goettsch, C., Erb, K., Fecher-Trost, C., Reil, J. C., Linz, B., Ruf, S., Hübschle, T., Maack, C., Böhm, M., Sadowski, T. & Linz, D., 4 Sep 2020, In: The Journal of biological chemistry. 295, 36, p. 12605-12617 13 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1074/jbc.RA120.013488 Right Ventricle Has Normal Myofilament Function But Shows Perturbations in the Expression of Extracellular Matrix Genes in Patients With Tetralogy of Fallot Undergoing Pulmonary Valve Replacement Brayson, D., Holohan, S. J., Bardswell, S. C., Arno, M., Lu, H., Jensen, H. K., Tran, P. K., Barallobre-Barreiro, J., Mayr, M., Dos Remedios, C. G., Tsang, V. T., Frigiola, A. & Kentish, J. C., 18 Aug 2020, In: Journal of the American Heart Association. 9, 16, p. e015342 Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1161/JAHA.119.015342 The right ventricle of Tetralogy of Fallot patients undergoing pulmonary valve replacement has normal myofilament function but shows perturbations to the expression of extracellular matrix genes Brayson, D., Holohan, S-J., Bardswell, S. C., Arno, M., Lu, H., Jensen, H. K., Kiet Tran, P., Barallobre-Barreiro, J., Mayr, M., G.dos Remedios, C., T. Tsang, V., Frigiola, A. & Kentish, J., 28 May 2020, (Accepted/In press) In: Journal of the American Heart Association. Research output: Contribution to journal › Article › peer-review Extracellular Matrix in Vascular Disease, Part 2/4: JACC Focus Seminar Barallobre-Barreiro, J., Loeys, B., Mayr, M., Rienks, M., Verstraeten, A. & Kovacic, J. C., 5 May 2020, In: Journal of the American College of Cardiology. 75, 17, p. 2189-2203 15 p. Research output: Contribution to journal › Review article › peer-review. DOIs: https://doi.org/10.1016/j.jacc.2020.03.018 Cartilage-like composition of keloid scar extracellular matrix suggests fibroblast mis-differentiation in disease Barallobre-Barreiro, J., Woods, E., Bell, R. E., Easton, J. A., Hobbs, C., Eager, M., Baig, F., MacKenzie Ross, A., Mallipeddi, R., Powell, B., Soldin, M., Mayr, M. & Shaw, T. J., 30 Oct 2019, (E-pub ahead of print) In: Matrix Biology Plus. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.mbplus.2019.100016 View all publications
1 December 2021 Beta-blockers reduce heart proteoglycan content potentially providing newly discovered health benefits Researchers discover that beta-blockers can prevent build-up of proteoglycans, a group of proteins…