Dr Espe Perucha Academics Lecturer in Experimental Rheumatology Contact details esperanza.perucha@kcl.ac.uk +44 (0) 20 7848 8636 @SpLAB_KCL
Cholesterol metabolism drives regulatory B cell IL-10 through provision of geranylgeranyl pyrophosphate Bibby, J., Purvis, H., Hayday, T., Cope, A. & Perucha, E., 4 May 2020, (Accepted/In press) In : Nature Communications. NCOMMS-19-37939D. Research output: Contribution to journal - Article Mechanisms of checkpoint inhibition induced adverse events Urwyler, P., Earnshaw, I., Bermudez, M., Perucha, E., Wu, W., Ryan, S., Mcdonald, L., Karagiannis, S. N., Taams, L. S., Powell, N., Cope, A. & Papa, S., 1 May 2020, In : Clinical and Experimental Immunology. 200, 2, p. 141-154 14 p. Research output: Contribution to journal - Review article. DOIs: https://doi.org/10.1111/cei.13421 Pathology of immune-mediated tissue lesions following treatment with immune checkpoint inhibitors Ibraheim, H., Perucha, E. & Powell, N., 1 Dec 2019, In : Rheumatology (Oxford, England). 58, 7, p. vii17-vii28 Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1093/rheumatology/kez465 The impact of donor and recipient common clinical and genetic variation on estimated glomerular filtration rate in a European renal transplant population The UK Ireland Renal Transplant Consortium, DeKAF Genomics and GEN03 Studies & The International Genetics and Translational Research in Transplantation Network, 1 Aug 2019, In : American Journal of Transplantation. 19, 8, p. 2262-2273 12 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1111/ajt.15326 The cholesterol biosynthesis pathway regulates IL-10 expression in human Th1 cells Perucha, E., Melchiotti, R., Bibby, J. A., Wu, W., Frederiksen, K. S., Roberts, C. A., Hall, Z., LeFriec, G., Robertson, K. A., Lavender, P., Gerwien, J. G., Taams, L. S., Griffin, J. L., de Rinaldis, E., van Baarsen, L. G. M., Kemper, C., Ghazal, P. & Cope, A. P., 2019, In : Nature Communications. 10, 1, 13 p., 498. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1038/s41467-019-08332-9 Long- and short-term outcomes in renal allografts with deceased donors: A large recipient and donor genome-wide association study United Kingdom and Ireland Renal Transplant Consortium (UKIRTC) and the Wellcome Trust Case Control Consortium (WTCCC)-3, Jun 2018, In : American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1111/ajt.14594 Interleukin 6 increases production of cytokines by colonic innate lymphoid cells in mice and patients with chronic intestinal inflammation Powell, N., Lo, J. W., Biancheri, P., Vossenkämper, A., Pantazi, E., Walker, A. W., Stolarczyk, E., Ammoscato, F., Goldberg, R., Scott, P., Canavan, J. B., Perucha, E., Garrido-Mesa, N., Irving, P. M., Sanderson, J. D., Hayee, B., Howard, J. K., Parkhill, J., MacDonald, T. T. & Lord, G. M., 1 Aug 2015, In : Gastroenterology. 149, 2, p. 456-467.e15 Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1053/j.gastro.2015.04.017 C3a modulates IL-1β secretion in human monocytes by regulating ATP efflux and subsequent NLRP3 inflammasome activation Asgari, E., Le Friec, G., Yamamoto, H., Perucha, E., Sacks, S. S., Köhl, J., Cook, H. T. & Kemper, C., 14 Nov 2013, In : Blood. 122, 20, p. 3473-3481 9 p., N/A. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1182/blood-2013-05-502229 Integration of lyoplate based flow cytometry and computational analysis for standardized immunological biomarker discovery Villanova, F., Di Meglio, P., Inokuma, M., Aghaeepour, N., Perucha, E., Mollon, J., Nomura, L., Hernandez Fuentes, M., Cope, A., Prevost, A. T., Heck, S., Maino, V., Lord, G., Brinkman, R. R. & Nestle, F. O., 3 Jul 2013, In : PLoS ONE. 8, 7, 8 p., e65485. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1371/journal.pone.0065485 Improved Insulin Sensitivity despite Increased Visceral Adiposity in Mice Deficient for the Immune Cell Transcription Factor T-bet Stolarczyk, E., Vong, C. T., Perucha, E., Jackson, I., Cawthorne, M. A., Wargent, E. T., Powell, N., Canavan, J. B., Lord, G. M. & Howard, J. K., 2 Apr 2013, In : CELL METABOLISM. 17, 4, p. 520-533 14 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1016/j.cmet.2013.02.019 View all publications