Dr Espe Perucha Academics Supervisors Lecturer in Experimental Rheumatology Research subject areas Immunology Contact details esperanza.perucha@kcl.ac.uk +44 (0) 20 7848 8636 @SpLAB_KCL
Regulatory B cell repertoire defects predispose lung cancer patients to immune-related toxicity following checkpoint blockade Patel, A. J., Willsmore, Z. N., Khan, N., Richter, A., Naidu, B., Drayson, M. T., Papa, S., Cope, A., Karagiannis, S. N., Perucha, E. & Middleton, G. W., 7 Jun 2022, In: Nature Communications. 13, 1, p. 3148 3148. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41467-022-30863-x T follicular cells: The regulators of germinal center homeostasis Ribeiro, F., Perucha, E. & Graca, L., Apr 2022, In: Immunology Letters. 244, p. 1-11 11 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.imlet.2022.02.008 Resilient SARS-CoV-2 diagnostics workflows including viral heat inactivation Lista, M. J., Matos, P. M., Maguire, T. J. A., Poulton, K., Ortiz-Zapater, E., Page, R., Sertkaya, H., Ortega-Prieto, A. M., Scourfield, E., O'Byrne, A. M., Bouton, C., Dickenson, R. E., Ficarelli, M., Jimenez-Guardeño, J. M., Howard, M., Betancor, G., Galao, R. P., Pickering, S., Signell, A. W., Wilson, H. & 17 others, Cliff, P., Kia Ik, M. T., Patel, A., MacMahon, E., Cunningham, E., Doores, K., Agromayor, M., Martin-Serrano, J., Perucha, E., Mischo, H. E., Shankar-Hari, M., Batra, R., Edgeworth, J., Zuckerman, M., Malim, M. H., Neil, S. & Martinez-Nunez, R. T., 15 Sep 2021, In: PLoS ONE. 16, 9 September, e0256813. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1371/journal.pone.0256813 Cholesterol metabolism: a new molecular switch to control inflammation Perucha, E., 4 Jun 2021, In: Clinical Science. 135, 11, p. 1389-1408 20 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1042/CS20201394 Resilient SARS-CoV-2 diagnostics workflows including viral heat inactivation Lista, M. J., Matos, P. M., Maguire, T. J. A., Poulton, K., Ortiz-Zapater, E., Page, R., Sertkaya, H., Ortega-Prieto, A. M., O'Byrne, A. M., Bouton, C., Dickenson, R. E., Ficarelli, M., Jimenez-Guardeño, J. M., Howard, M., Betancor, G., Galao, R. P., Pickering, S., Signell, A. W., Wilson, H., Cliff, P. & 16 others, Ik, M. T. K., Patel, A., MacMahon, E., Cunningham, E., Doores, K., Agromayor, M., Martin-Serrano, J., Perucha, E., Mischo, H. E., Shankar-Hari, M., Batra, R., Edgeworth, J., Zuckerman, M., Malim, M. H., Neil, S. & Martinez-Nunez, R. T., 10 Apr 2021, (MedRxiv). Research output: Working paper/Preprint › Preprint. DOIs: https://doi.org/10.1101/2020.04.22.20074351 Cholesterol metabolism drives regulatory B cell IL-10 through provision of geranylgeranyl pyrophosphate Bibby, J., Purvis, H., Hayday, T., Cope, A. & Perucha, E., 8 Jul 2020, In: Nature Communications. 11, 12 p., 3412 . Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41467-020-17179-4 Mechanisms of checkpoint inhibition induced adverse events Urwyler, P., Earnshaw, I., Bermudez, M., Perucha, E., Wu, W., Ryan, S., Mcdonald, L., Karagiannis, S. N., Taams, L. S., Powell, N., Cope, A. & Papa, S., 16 Apr 2020, In: Clinical and Experimental Immunology. 200, 2, p. 141-154 14 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1111/cei.13421 Pathology of immune-mediated tissue lesions following treatment with immune checkpoint inhibitors Ibraheim, H., Perucha, E. & Powell, N., 1 Dec 2019, In: Rheumatology (Oxford, England). 58, 7, p. vii17-vii28 Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1093/rheumatology/kez465 The impact of donor and recipient common clinical and genetic variation on estimated glomerular filtration rate in a European renal transplant population The UK Ireland Renal Transplant Consortium, DeKAF Genomics and GEN03 Studies & The International Genetics and Translational Research in Transplantation Network, 1 Aug 2019, In: American Journal of Transplantation. 19, 8, p. 2262-2273 12 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1111/ajt.15326 The cholesterol biosynthesis pathway regulates IL-10 expression in human Th1 cells Perucha, E., Melchiotti, R., Bibby, J., Wu, W., Stensgaard Frederiksen, K., Roberts, C., Hall, Z., LeFriec, G., Robertson, K., Lavender, P., Gammeltoft Gerwien, J., Taams, L., Griffin, J., de Rinaldis, E., van Baarsen, L., Kemper, C., Ghazal, P. & Cope, A., 30 Jan 2019, In: Nature Communications. 10, 1, 13 p., 498. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41467-019-08332-9 View all publications