Gemma Modinos Professor Gemma Modinos PhD FYAE MAE Supervisors Professor of Neuroscience & Mental Health Research subject areas Neuroscience Psychology Pharmacology Contact details gemma.modinos@kcl.ac.uk 020 7848 0927 Pronouns she/her
Description Gemma is module lead for the Biological Psychiatry module of the MSc Psychiatric Research, and a supervisor to PhD students.
Multivariable prediction of functional outcome after first-episode psychosis: a crossover validation approach in EUFEST and PSYSCAN GABAA receptor availability in clinical high-risk and first-episode psychosis: a [11C]Ro15-4513 positron emission tomography study Diazepam modulates hippocampal CA1 functional connectivity in people at clinical high-risk for psychosis Transcriptional and Neurochemical Signatures of Cerebral Blood Flow Alterations in Individuals With Schizophrenia or at Clinical High Risk for Psychosis Transcriptional and neurochemical signatures of cerebral blood flow alterations in schizophrenia and individuals at clinical high-risk for psychosis Association between Adverse Childhood Experiences and long-term outcomes in people at Clinical High-Risk for Psychosis Towards a consensus roadmap for a new diagnostic framework for mental disorders Corticolimbic circuitry as a druggable target in schizophrenia spectrum disorders: a narrative review From Speech Illusions to Onset of Psychotic Disorder: Applying Network Analysis to an Experimental Measure of Aberrant Experiences The effects of recent stressful life events on outcomes in individuals at clinical high risk for psychosis: results from the longitudinal EU-GEI high-risk study Transcriptional and neurochemical signatures of cerebral blood flow alterations in schizophrenia and the clinical high-risk state for psychosis Childhood trauma moderates schizotypy-related brain morphology: Analyses of 1182 healthy individuals from the ENIGMA schizotypy working group Neurochemical models of psychosis risk and onset Do Cognitive Subtypes Exist in People at Clinical High Risk for Psychosis? Results from the EU-GEI Study Cellular and molecular signatures of in vivo imaging measures of GABAergic neurotransmission in the human brain PsyCog: A computerised mini battery for assessing cognition in psychosis Correction: Adverse clinical outcomes in people at clinical high-risk for psychosis related to altered interactions between hippocampal activity and glutamatergic function (Translational Psychiatry, (2021), 11, 1, (579), 10.1038/s41398-021-01705-z) Effects of diazepam on hippocampal blood flow in people at clinical high risk for psychosis Effects of Benzodiazepine Exposure on Real-World Clinical Outcomes in Individuals at Clinical High-Risk for Psychosis Letter to the Editor on 'Baseline benzodiazepine exposure is associated with greater risk of transition in clinical high-risk for psychosis (CHR-P): a meta-analysis' Variability and magnitude of brain glutamate levels in schizophrenia: a meta and mega-analysis Correction: Hippocampal circuit dysfunction in psychosis Hippocampal circuit dysfunction in psychosis Parsing neurobiological heterogeneity of the clinical high-risk state for psychosis: A pseudo-continuous arterial spin labelling study Neurofunctional correlates of glutamate and GABA imbalance in psychosis: A systematic review Speech Illusions in People at Clinical High Risk for Psychosis Linked to Clinical Outcome Erbb4 deletion from inhibitory interneurons causes psychosis-relevant neuroimaging phenotypes Local molecular and global connectomic contributions to cross-disorder cortical abnormalities Are Brain Responses to Emotion a Reliable Endophenotype of Schizophrenia? An Image-Based Functional Magnetic Resonance Imaging Meta-analysis Hippocampal circuit dysfunction in psychosis The relationship between grey matter volume and clinical and functional outcomes in people at clinical high risk for psychosis Schizophrenia: A developmental disorder with a risk of non-specific but avoidable decline Cellular and molecular signatures of in vivo imaging measures of GABAergic neurotransmission in the human brain Relationship between cortical glutamatergic metabolite levels and hippocampal activity in schizotypy GABAA and NMDA receptor density alterations and their behavioral correlates in the gestational methylazoxymethanol acetate model for schizophrenia Verbal memory performance predicts remission and functional outcome in people at clinical high-risk for psychosis Cortical and subcortical neuroanatomical signatures of schizotypy in 3004 individuals assessed in a worldwide ENIGMA study Cortical and Subcortical Neuroanatomical Signatures of Schizotypy in 3,004 Individuals Assessed in a Worldwide ENIGMA Study Adverse clinical outcomes in people at clinical high-risk for psychosis related to altered interactions between hippocampal activity and glutamatergic function Stress reactivity as a putative mechanism linking childhood trauma with clinical outcomes in individuals at ultra-high-risk for psychosis: Findings from the EU-GEI High risk study Association of Age, Antipsychotic Medication, and Symptom Severity in Schizophrenia with Proton Magnetic Resonance Spectroscopy Brain Glutamate Level: A Mega-analysis of Individual Participant-Level Data Interactions between hippocampal activity and striatal dopamine in people at clinical high risk for psychosis: relationship to adverse outcomes Neural correlates of emotional processing in psychosis risk and onset – a systematic review and meta-analysis of fMRI studies GABA, glutamate and neural activity: a systematic review with meta-analysis of multimodal 1H-MRS-fMRI studies Cognitive functioning throughout adulthood and illness stages in individuals with psychotic disorders and their unaffected siblings Pre-training inter-rater reliability of clinical instruments in an international psychosis research project Region-specific and dose-specific effects of chronic haloperidol exposure on [3H]-flumazenil and [3H]-Ro15-4513 GABAA receptor binding sites in the rat brain Integrated metastate functional connectivity networks predict change in symptom severity in clinical high risk for psychosis CORTICAL NEUROANATOMICAL SIGNATURE OF SCHIZOTYPY IN 2,695 INDIVIDUALS ASSESSED IN A WORLDWIDE ENIGMA STUDY Neuroanatomical Correlates of Psychotic-Like Experiences Assessed in 2,695 Individuals via the ENIGMA Consortium View all publications
8 August 2024 Professor Gemma Modinos elected to Academia Europaea Professor Modinos joins the ranks of outstanding scientists as a Fellow of the Academia Europaea.