Dr James Clark Academics Supervisors Reader in Physiology Education Research subject areas Cardiovascular Contact details james.2.clark@kcl.ac.uk +44 (0) 20 7188 0966 @KclPhysiology
p38γ MAPK contributes to left ventricular remodeling after pathologic stress and disinhibits calpain through phosphorylation of calpastatin Loonat, A. A., Martin, E. D., Sarafraz-Shekary, N., Tilgner, K., Hertz, N. T., Levin, R., Shokat, K. M., Burlingame, A. L., Arabacilar, P., Uddin, S., Thomas, M., Marber, M. S. & Clark, J. E., 31 Dec 2019, In: Faseb Journal. 33, 12, p. 13131-13144 14 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1096/fj.201701545R The POU4F2/Brn-3b transcription factor is required for the hypertrophic response to angiotensin II in the heart Mele, L., Maskell, L. J., Stuckey, D. J., Clark, J. E., Heads, R. J. & Budhram-mahadeo, V. S., 14 Aug 2019, In: Cell death & disease. 10, 8, p. 621-638 18 p., 621. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41419-019-1848-y Aged-senescent cells contribute to impaired heart regeneration Lewis-McDougall, F. C., Ruchaya, P. J., Domenjo-Vila, E., Teoh, T. S., Prata, L., Cottle, B. J., Clark, J. E., Punjabi, P. P., Awad, W., Torella, D., Tchkonia, T., Kirkland, J. L. & Ellison-Hughes, G. M., Jun 2019, In: AGING CELL. 18, 3, e12931. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1111/acel.12931 Tissue acidosis does not mediate the hypoxia selectivity of [64Cu][Cu(ATSM)] in the isolated perfused rat heart Baark, F., Shaughnessy, F., Pell, V. R., Clark, J. E., Eykyn, T. R., Blower, P. & Southworth, R., 24 Jan 2019, In: Scientific Reports. 9, 10 p., 499. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41598-018-36145-1 Detection of anthracycline-induced cardiotoxicity using perfusion-corrected 99mTc sestamibi SPECT Safee, Z. M., Baark, F., Waters, E. C. T., Veronese, M., Pell, V. R., Clark, J. E., Mota, F., Livieratos, L., Eykyn, T. R., Blower, P. J. & Southworth, R., 2019, In: Scientific Reports. 9, p. 216-227 11 p., 216. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41598-018-36721-5 Dynamic heart rate response to multi-day unsupported ultra-endurance cycle racing: a case report Brayson, D., Frigiola, A. & Clark, J. E., 12 Dec 2018, (Accepted/In press) In: Experimental Physiology. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1113/EP087341 The TAB1-p38α complex aggravates myocardial injury and can be targeted by small molecules De Nicola, G. F., Bassi, R., Nichols, C., Fernandez-Caggiano, M., Golforoush, P. A., Thapa, D., Anderson, R., Martin, E. D., Verma, S., Kleinjung, J., Laing, A., Hutchinson, J. P., Eaton, P., Clark, J. & Marber, M. S., 23 Aug 2018, In: JCI Insight. 3, 16, p. 1-17 Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1172/jci.insight.121144 Pravastatin therapy during preeclampsia prevents long-term adverse health effects in mice Garrett, N., Pombo, J., Umpierrez, M., Clark, J. E., Simmons, M. & Girardi, G., 19 Apr 2018, (E-pub ahead of print) In: JCI Insight. 3, 8 Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1172/jci.insight.120147 Author Correction: Non-Invasive whole-body detection of complement activation using radionuclide imaging in a mouse model of myocardial ischaemia-reperfusion injury Sharif-Paghaleh, E., Yap, M. L., Puhl, S. L., Badar, A., Torres, J. B., Chuamsaamarkkee, K., Kampmeier, F., Smith, R. A., Clark, J., Blower, P. J., Sacks, S. & Mullen, G. E., 13 Mar 2018, In: Scientific Reports. 8, 1, p. 4687 1 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41598-018-22722-x Cardioprotection by an anti-MASP-2 antibody in a murine model of myocardial infarction Clark, J. E., Dudler, T., Marber, M. S. & Schwaeble, W., 2018, In: Open Heart. 5, e000652. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1136/openhrt-2017-000652 View all publications
7 January 2020 Dr James Clark wins Otto Hutter physiology prize Dr James Clark, School of Cardiovascular Medicine & Sciences, has been awarded the 2019 Otto Hutter…