Biography
Dr James Clark has a degree in Applied Biology from the University of Bath and a PhD in Surgery from University College London. Working on the processes involved in ischaemic and pharmacological preconditioning during his PhD and subsequent post-doctoral research he was part of the team to develop novel carbon monoxide releasing molecules (CORMs) which can be used to elucidate the functional role of carbon monoxide in biological systems and led to the formation of the start-up company (HemoCORM).
In 2003 he was appointed a Research Associate in the Cardiovascular Division at King’s where he joined the group of Prof. Mike Marber and continued research on cardiac-protection and pharmacological preconditioning. In 2007, Dr Clark was awarded a British Heart Foundation (BHF) Intermediate Research Fellowship to carry out work on carbon monoxide-mediated cardio-protection. In February 2010, he was appointed to a Lectureship in Aerospace Physiology within the academic department of Physiology to teach on undergraduate and masters’ level courses. Dr Clark was promoted to the post of Reader in Human & Applied Physiology in 2019.
Dr Clark’s research interests span whole body integrative and applied physiology including, hyperbaric and diving medicine, and the mechanisms that control cardiac function in health and disease. His interests in cardiac physiology lead to a number of fruitful collaborations as well as pushing forward his own research interests in acute myocardial infarction and heart failure.
James is currently director of the Human & Applied Physiology MSc, admissions tutor for Dept. Physiology and Academic lead for Education in the School of Cardiovascular Medicine and Sciences.
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Loonat, A. A., Martin, E. D., Sarafraz-Shekary, N., Tilgner, K., Hertz, N. T., Levin, R., Shokat, K. M., Burlingame, A. L., Arabacilar, P., Uddin, S., Thomas, M., Marber, M. S. & Clark, J. E., Dec 2019, In : Faseb Journal. 33, 12, p. 13131-13144 14 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1096/fj.201701545R
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Mele, L., Maskell, L. J., Stuckey, D. J., Clark, J. E., Heads, R. J. & Budhram-mahadeo, V. S., 14 Aug 2019, In : Cell death & disease. 10, 8, p. 621-638 18 p., 621. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1038/s41419-019-1848-y
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Lewis-McDougall, F. C., Ruchaya, P. J., Domenjo-Vila, E., Teoh, T. S., Prata, L., Cottle, B. J., Clark, J. E., Punjabi, P. P., Awad, W., Torella, D., Tchkonia, T., Kirkland, J. L. & Ellison-Hughes, G. M., Jun 2019, In : AGING CELL. 18, 3, e12931. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1111/acel.12931
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Baark, F., Shaughnessy, F., Pell, V. R., Clark, J. E., Eykyn, T. R., Blower, P. & Southworth, R., 24 Jan 2019, In : Scientific Reports. 9, 10 p., 499. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1038/s41598-018-36145-1
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Safee, Z. M., Baark, F., Waters, E. C. T., Veronese, M., Pell, V. R., Clark, J. E., Mota, F., Livieratos, L., Eykyn, T. R., Blower, P. J. & Southworth, R., 2019, In : Scientific Reports. 9, p. 216-227 11 p., 216. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1038/s41598-018-36721-5
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Brayson, D., Frigiola, A. & Clark, J. E., 12 Dec 2018, (Accepted/In press) In : Experimental Physiology. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1113/EP087341
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De Nicola, G. F., Bassi, R., Nichols, C., Fernandez-Caggiano, M., Golforoush, P. A., Thapa, D., Anderson, R., Martin, E. D., Verma, S., Kleinjung, J., Laing, A., Hutchinson, J. P., Eaton, P., Clark, J. & Marber, M. S., 23 Aug 2018, In : JCI Insight. 3, 16 Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1172/jci.insight.121144
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Garrett, N., Pombo, J., Umpierrez, M., Clark, J. E., Simmons, M. & Girardi, G., 19 Apr 2018, In : JCI Insight. 3, 8 Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1172/jci.insight.120147
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Sharif-Paghaleh, E., Yap, M. L., Puhl, S. L., Badar, A., Torres, J. B., Chuamsaamarkkee, K., Kampmeier, F., Smith, R. A., Clark, J., Blower, P. J., Sacks, S. & Mullen, G. E., 13 Mar 2018, In : Scientific Reports. 8, 1, p. 4687 1 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1038/s41598-018-22722-x
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Clark, J. E., Dudler, T., Marber, M. S. & Schwaeble, W., 2018, In : Open Heart. 5, e000652. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1136/openhrt-2017-000652