Biography

My research aims to understand the role of brain chemistry in mental illness and to identify different subtypes of Illness that might show different responses to drug treatments. In particular I am interested in how differences in brain glutamate levels may predict response to antipsychotic drugs and antidepressants. I am also involved in research on the gut microbiome and it's role in depression and anxiety, as well as on ketamine and psilocybin in the treatment of depression and post-traumatic stress disorder (PTSD). My research encompasses a variety of methods including clinical trials, magnetic resonance imaging (MRI) imaging and psychological testing.

Please see my Research Staff Profile for more detail

Key publications:

• Stone et al., 2007. Glutamate and dopamine dysregulation in schizophrenia—a synthesis and selective review. Journal of  Psychopharmacology.
• Stone et al., 2012. Ketamine effects on brain GABA and glutamate levels with 1H-MRS: relationship to ketamine-induced psychopathology. Molecular Psychiatry.
• Egerton et al., 2012. Anterior cingulate glutamate levels related to clinical status following treatment in first-episode schizophrenia. Neuropsychopharmology.