Mario is a Reader in Computational Medicine at King’s College London, and Head of Bioinformatics for the School of Life Course & Population Sciences. His interests lie in the development and application of statistical and computational genomics methods to disentangle the network of susceptibility factors – and their interactions – that lead to complex disease in humans, with a particular focus on metabolism, skin cancer, and renal diseases.

Recently his team has been focusing on leveraging next generation sequencing technologies to assess the influence of rare and structural variants on complex traits, and on characterisation of the microbiome using metagenomics data to investigate the interplay between the gut microbiota and host metabolism.