Professor Mark Sutton
Professor for Antimicrobial Therapy
My research interests are mainly in bacterial pathogenesis and virulence, the development and evaluation of novel antimicrobial agents and rapid detection and diagnostic systems. My group across KCL and UKHSA, uses a variety of techniques to develop real life solutions to practical problems, working closely with end users, academic groups and commercial parties. The group takes an interdisciplinary approach working with a variety of groups in life sciences, chemistry and physical sciences. Specific areas include:
- Antimicrobial development. A rapidly expanding area of research has developed as a collaboration between my group and a number of academic collaborators in the UK, India, USA, Australia. This multidisciplinary activity brings together complementary skills in medicinal chemistry, membrane biophysics and microbiology, with the aim of developing novel antimicrobial leads for treatment of multidrug resistant organisms and understanding novel mechanisms of action. The activity has also catalysed further studies with a number of partners looking at both small molecule and alternative antimicrobial strategies, including phage therapy, novel antimicrobial peptides and immunomodulator, applied to pathogenic bacteria, fungi and viruses.
- Rapid detection and diagnosis. Current work focusses on developing new approaches for rapid measurement of antimicrobial susceptibility, for both established and novel antimicrobials, working with colleagues on a number of interdisciplinary projects.