Professor Maya Thanou Professor Maya Thanou Academics Supervisors Research subject areas Pharmacy Contact details maya.thanou@kcl.ac.uk +44 (0) 20 7848 4831 @MayaThanou
Engineered extracellular vesicles demonstrate altered endocytosis and biodistribution and have superior oral siRNA delivery efficiency compared to lipid nanoparticles Sonodynamic therapy: transforming sound into light for hard-to-treat tumours Unveiling the enigma of the blood–brain barrier in glioblastoma: current advances from preclinical and clinical studies Ex-vivo Dielectric Properties of Tissues in Athymic Nude Mice Effect of Phase-Change Nanodroplets and Ultrasound on Blood–Brain Barrier Permeability In Vitro Hybrid Milk Extracellular Vesicles as Potential Systems for Oral Delivery of siRNA Desgin of Nanoparticles for Focused Ultrasound Drug Delivery Characterising the chemical and physical properties of phase-change nanodroplets Development of Cationic Lipid LAH4-L1 siRNA Complexes for Focused Ultrasound Enhanced Tumor Uptake Preparation and Purification of Calcein Loaded Temperature-Sensitive Liposomes Ex-vivo Dielectric Properties of Tissues in Athymic Nude Mice Phase-shift nanodroplets as an emerging sonoresponsive nanomaterial for imaging and drug delivery applications Manipulating the Barrier Function of a Cell Monolayer Using a High-power Miniature Ultrasonic Transducer Calcium phosphate nanoparticles for potential application as enamel remineralising agent tested on hydroxyapatite discs Nanomaterials responding to microwaves: an emerging field for imaging and therapy Image-guided thermosensitive liposomes for focused ultrasound enhanced co-delivery of carboplatin and SN-38 against triple negative breast cancer in mice MR-labelled liposomes and focused ultrasound for spatiotemporally controlled drug release in triple negative breast cancers in mice Ultrasound mediated delivery of quantum dots from a proof of concept capsule endoscope to the gastrointestinal wall Emerging nanomaterials for dental treatments An Organoid-derived Cell Layer as an in vitro Model for US-mediated Drug Delivery Studies Assessing changes in dielectric properties due to nanomaterials using a two-port microwave system Exploiting disease-induced changes for targeted oral delivery of biologics and nanomedicines in inflammatory bowel disease Design of nanoparticles for focused ultrasound drug delivery Feasibility Experiments to Detect Skin Hydration Using a Bio-Impedance Sensor Thermosensitive liposome-mediated drug delivery in chemotherapy: Mathematical modelling for spatio–temporal drug distribution and model-based optimisation Examination of zinc ferrites vs. iron oxides as contrast agents for microwave systems An atom efficient, single-source precursor route to plasmonic CuS nanocrystals A glassware-free combinatorial synthesis of green quantum dots using bubble wrap Ultrasound and Microbubbles Promote the Retention of Fluorescent Compounds in the Small Intestine Preliminary Assessment of a Microwave System to Detect Contrast Enhancing Agents CHAPTER 9: Microwave Imaging and the Potential of Contrast Enhancing Agents for Theranostics Use Zinc oxide nanoparticles as contrast-enhancing agents for microwave imaging Recent advances in oral delivery of biologics: nanomedicine and physical modes of delivery Image guided thermosensitive liposomes for focused ultrasound drug delivery: Using NIRF labelled lipids and topotecan to visualise the effects of hyperthermia in tumours CHAPTER 1: Image Guided Focused Ultrasound as a New Method of Targeted Drug Delivery Characterisation of ZnO NPs as contrast agents for MWI Cytotoxicity of Polycations: Relationship of Molecular Weight and the Hydrolytic Theory of the Mechanism of Toxicity An in vitro sonication system for applications in ultrasound-mediated targeted drug delivery Focused ultrasound induced hyperthermia accelerates and increases the uptake of anti-HER-2 antibodies in a xenograft model Focused Ultrasound Induced Hyperthermia Accelerates and Increases the Uptake of anti-Her2 Antibodies in a Xenograft Model Hydrophobin-Encapsulated Quantum Dots Carbon Nanopipe Dispersions in aqueous solutions and their effect on cell viability How Much Advantage do Nanoscale Phenomena Afford for Pulmonary Delivery? Intestinal absorption of octreotide: N-trimethyl chitosan chloride (TMC) ameliorates the permeability and absorption properties of the somatostatin analogue in vitro and in vivo MRI-Guided Focused Ultrasound as a New Method of Drug Delivery Effect of the degree of quaternization of N-trimethyl chitosan chloride on the permeability of intestinal epithelial cells (Caco-2) Enhancement of paracellular drug transport with highly quaternized N-trimethyl chitosan chloride in neutral environments: In vitro evaluation in intestinal epithelial cells (Caco-2) N-trimethylated chitosan chloride (TMC) improves the intestinal permeation of the peptide drug buserelin in vitro (Caco-2 cells) and in vivo (rats) Effect of degree of quaternization of N-trimethyl chitosan chloride for enhanced transport of hydrophilic compounds across intestinal Caco-2 cell monolayers Enhancement of bronchial octreotide absorption by chitosan and N-trimethyl chitosan shows linear in vitro/in vivo correlation View all publications
5 June 2025 King's researchers make splash at CRH Innovation and Entrepreneurship Awards 2025 A wide cohort of researchers from King’s have been shortlisted for the Cancer Research Horizons…