Professor Miraz Rahman Academics Supervisors Professor of Medicinal Chemistry Research subject areas Chemistry Contact details k.miraz.rahman@kcl.ac.uk +44 (0) 20 7848 1891 @mrahmanlab
Covalent DNA Binding Is Essential for Gram-Negative Antibacterial Activity of Broad Spectrum Pyrrolobenzodiazepines Picconi, P., Mark Sutton, J., Hind, C. K. & Rahman, M., 7 Dec 2022, In: Antibiotics. p. 1-10 10 p., 1770. Research output: Contribution to journal › Article › peer-review Development and exploration of novel substituted thiosemicarbazones as inhibitors of aldose reductase via in vitro analysis and computational study Imran, A., Shehzad, M. T., Shah, S. J. A., al Adhami, T., Laws, M., Rahman, K. M., Alharthy, R. D., Khan, I. A., Shafiq, Z. & Iqbal, J., Dec 2022, In: Scientific Reports. 12, 1, 5734. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41598-022-09658-z Isolation and In Silico Prediction of Potential Drug-like Compounds with a New Dimeric Prenylated Quinolone Alkaloid from Zanthoxylum rhetsa (Roxb.) Root Extracts Targeted against SARS-CoV-2 (Mpro) Tuz Zohra, F., Azam, ATM. Z., Ahmed, S., Halim, M., Rahman, M., Anwar, M. R., Sohrab, M. H., Tabassum, F., Hasan, C. M. & Ahsan, M., 24 Nov 2022, In: Molecules (Basel, Switzerland). 27, 23, p. 1 15 p., 8191. Research output: Contribution to journal › Article › peer-review Identification and characterisation of G-quadruplex DNA-forming sequences in the Pseudomonas aeruginosa genome Evans, L., Kotar, A., Valentini, M., Filloux, A., Jamshidi, S., Plavec, J., Rahman, M. & Vilar, R., 15 Nov 2022, In: RSC Chemical Biology. 18 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1039/d2cb00205a Mechanistic insight into the repair of C8-linked pyrrolobenzodiazepine monomer-mediated DNA damage Joseph, A. M., Nahar, K., Daw, S., Hasan, M., Lo, R., Le, T., Rahman, M. & Badrinarayanan, A., 18 Oct 2022, (E-pub ahead of print) In: RSC Medicinal Chemistry. 32, 2, p. 1-13 13 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1039/d2md00194b Development, Molecular Docking, and in Silico ADME Evaluation of Selective ALR2 Inhibitors for the Treatment of Diabetic Complications via Suppression of the Polyol Pathway Imran, A., Shehzad, M. T., Shah, S. J. A., Laws, M., Al-Adhami, T., Rahman, K. M., Khan, I. A., Shafiq, Z. & Iqbal, J., 2 Aug 2022, In: ACS Omega. 7, 30, p. 26425-26436 12 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1021/acsomega.2c02326 DNA sequence-selective G-A cross-linking ADC payloads for use in solid tumour therapies Procopiou, G., Jackson, P. J. M., di Mascio, D., Auer, J. L., Pepper, C., Rahman, K. M., Fox, K. R. & Thurston, D. E., 29 Jul 2022, In: Communications Biology. 5, 1, p. 741 1 p., 741. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s42003-022-03633-0 Efflux pumps in Mycobacterium tuberculosis and their inhibition to tackle antimicrobial resistance Laws, M., Jin, P. & Rahman, K. M., Jan 2022, In: Trends in Microbiology. 30, 1, p. 57-68 12 p. Research output: Contribution to journal › Review article › peer-review. DOIs: https://doi.org/10.1016/j.tim.2021.05.001 Factors influencing the choice of monoclonal antibodies for antibody–drug conjugates Hasan, M., Jin, P., Laws, M. & Rahman, M., Jan 2022, In: DRUG DISCOVERY TODAY. 27, 1, p. 354-361 8 p. Research output: Contribution to journal › Review article › peer-review. DOIs: https://doi.org/10.1016/j.drudis.2021.09.015 Strategies for drug repurposing against coronavirus targets Smith, P., Rahman, M. & Jin, P., 2022, In: Current Research in Pharmacology and Drug Discovery. 3, p. 1-14 14 p., 100072. Research output: Contribution to journal › Review article › peer-review View all publications
11 October 2022 IPS colleagues win major awards at international PharmSci conference The awards included the Academy of Pharmaceutical Sciences' (APS) Science and Emerging Scientist…