Mohammad Mahdi Karimi Dr Mohammad Mahdi Karimi Academics Supervisors Senior Lecturer in Bioinformatics Research subject areas Biomedical and life sciences Contact details mohammad.karimi@kcl.ac.uk @MKarimi_KCL_Lab
Cohesin couples transcriptional bursting probabilities of inducible enhancers and promoters Robles-Rebollo, I., Cuartero, S., Canellas-Socias, A., Wells, S., Karimi, M. M., Mereu, E., Chivu, A. G., Heyn, H., Whilding, C., Dormann, D., Marguerat, S., Rioja, I., Prinjha, R. K., Stumpf, M. P. H., Fisher, A. G. & Merkenschlager, M., Dec 2022, In: Nature Communications. 13, 1, 4342. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41467-022-31192-9 RUNX1 Regulates a Transcription Program That Affects the Dynamics of Cell Cycle Entry of Naive Resting B Cells Thomsen, I., Kunowska, N., de Souza, R., Moody, A. M., Crawford, G., Wang, Y. F., Khadayate, S., Whilding, C., Strid, J., Karimi, M. M., Barr, A. R., Dillon, N. & Sabbattini, P., 15 Dec 2021, In: Journal of Immunology. 207, 12, p. 2976-2991 16 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.4049/jimmunol.2001367 INucs: Inter-nucleosome interactions Oveisi, M., Shukla, M., Seymen, N., Ohno, M., Taniguchi, Y., Nahata, S., Loos, R., Mufti, G. J., Allshire, R. C., DImitrov, S. & Karimi, M. M., 1 Dec 2021, In: BIOINFORMATICS. 37, 23, p. 4562-4563 2 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1093/bioinformatics/btab698 The order and logic of CD4 versus CD8 lineage choice and differentiation in mouse thymus Karimi, M. M., Guo, Y., Cui, X., Pallikonda, H. A., Horková, V., Wang, Y. F., Gil, S. R., Rodriguez-Esteban, G., Robles-Rebollo, I., Bruno, L., Georgieva, R., Patel, B., Elliott, J., Dore, M. H., Dauphars, D., Krangel, M. S., Lenhard, B., Heyn, H., Fisher, A. G., Štěpánek, O., & 1 othersMerkenschlager, M., Dec 2021, In: Nature Communications. 12, 1, 99. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41467-020-20306-w Cell competition acts as a purifying selection to eliminate cells with mitochondrial defects during early mouse development Lima, A., Lubatti, G., Burgstaller, J., Hu, D., Green, A. P., Di Gregorio, A., Zawadzki, T., Pernaute, B., Mahammadov, E., Perez-Montero, S., Dore, M., Sanchez, J. M., Bowling, S., Sancho, M., Kolbe, T., Karimi, M. M., Carling, D., Jones, N., Srinivas, S., Scialdone, A., & 1 othersRodriguez, T. A., Aug 2021, In: Nature Metabolism. 3, 8, p. 1091-1108 18 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s42255-021-00422-7 Surveillance of cohesin-supported chromosome structure controls meiotic progression Castellano-pozo, M., Pacheco, S., Sioutas, G., Jaso-tamame, A. L., Dore, M. H., Karimi, M. M. & Martinez-perez, E., 1 Dec 2020, In: Nature Communications. 11, 1, p. 4345 4345. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41467-020-18219-9 Evolution of an Amniote-Specific Mechanism for Modulating Ubiquitin Signaling via Phosphoregulation of the E2 Enzyme UBE2D3 Roman-trufero, M., Ito, C. M., Pedebos, C., Magdalou, I., Wang, Y., Karimi, M. M., Moyon, B., Webster, Z., Di Gregorio, A., Azuara, V., Khalid, S., Speck, C., Rodriguez, T., Dillon, N. & Yeager, M. (ed.), 1 Jul 2020, In: Molecular Biology and Evolution. 37, 7, p. 1986-2001 16 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1093/molbev/msaa060 CpG Islands Shape the Epigenome Landscape Papin, C., Le Gras, S., Ibrahim, A., Salem, H., Karimi, M. M., Stoll, I., Ugrinova, I., Schröder, M., Fontaine-Pelletier, E., Omran, Z., Bronner, C., Dimitrov, S. & Hamiche, A., 2020, (Accepted/In press) In: Journal of Molecular Biology. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.jmb.2020.09.018 FACT mediates cohesin function on chromatin Garcia-luis, J., Lazar-stefanita, L., Gutierrez-escribano, P., Thierry, A., Cournac, A., García, A., González, S., Sánchez, M., Jarmuz, A., Montoya, A., Dore, M., Kramer, H., Karimi, M. M., Antequera, F., Koszul, R. & Aragon, L., 1 Oct 2019, In: NATURE STRUCTURAL AND MOLECULAR BIOLOGY. 26, 10, p. 970-979 10 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41594-019-0307-x Hepatocyte Nuclear Factor 4‐Alpha Is Essential for the Active Epigenetic State at Enhancers in Mouse Liver Thakur, A., Wong, J. C. H., Wang, E. Y., Lotto, J., Kim, D., Cheng, J., Mingay, M., Cullum, R., Moudgil, V., Ahmed, N., Tsai, S., Wei, W., Walsh, C. P., Stephan, T., Bilenky, M., Fuglerud, B. M., Karimi, M. M., Gonzalez, F. J., Hirst, M. & Hoodless, P. A., 1 Oct 2019, In: Hepatology. 70, 4, p. 1360-1376 Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1002/hep.v70.4 View all publications