Biography
Natalie received her Ph.D. in Human Molecular Genetics from the UCL Institute of Child Health in 2000 and remained there to do her first postdoc on the complex genetics of cleft lip and palate. In 2001 she was awarded a UCL Bogue visiting fellowship to the McKusick-Nathans Institute of Genetic Medicine, John’s Hopkins, Baltimore, Maryland USA. She joined the Department of Medical and Molecular Genetics at King's in 2004 as a postdoc in Prof Chris Mathew’s lab investigating the genetic etiology of the inflammatory bowel diseases (IBD)’ Crohn’s disease (CD) and ulcerative colitis (UC).
In 2011 she received the prestigious Wellcome Trust University Award, a five-year Career Development Fellowship to begin her own independent research program investigating the functional importance of non-coding genome regions that have been strongly implicated in IBD through genome-wide association studies (GWAS). In 2017 she became a Lecturer in the Department of Medical and Molecular Genetics, King's. Her research interests include exploring the functional significance of genetic variations associated with IBD and orofacial granulomatosis (OFG).
Natalie is the group leader for the IBD and Complex Genetics Group.
Natalie is a course leader for the following courses:
- Molecular Basis of Gene Expression (5BBG0205)
- Molecular Biology Research Skills (5BBG0206)
Natalie is a teacher on the following courses:
- Complex Disease Genetics (6BBYG306)
- Extended Research Project in Genetics (6BBG0303)
- Human and Molecular Genetics (5BBG0204)
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Belgium IBD Consortium, Sep 2022, In: Nature genetics. 54, 9, p. 1275-1283 9 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41588-022-01156-2
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Goldberg, R., Clough, J. N., Roberts, L. B., Sanchez, J., Kordasti, S., Petrov, N., Hertweck, A., Lorenc, A., Jackson, I., Tasker, S., Appios, A., Omer, O., Parkes, M., Prescott, N., Jenner, R. G., Irving, P. M. & Lord, G. M., 18 Dec 2021, In: Journal of Crohn's & colitis. 15, 12, p. 2054-2065 12 p., jjab103. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1093/ecco-jcc/jjab103
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Prescott, N. J., Taylor, K. M. & Sanderson, J. D., 21 Jul 2020, (E-pub ahead of print) In: Clinical Gastroenterology and Hepatology : the official clinical practice journal of the American Gastroenterological Association. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.cgh.2020.06.020
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Parkes, M., Prescott, N., Mathew, C., Sanderson, J. & Irving, P., Sep 2019, In: Gut. 68, 9, p. 1537-1540 Research output: Contribution to journal › Letter › peer-review. DOIs: https://doi.org/10.1136/gutjnl-2019-318835
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Goel, R. M., Prosdocimi, E. M., Amar, A., Omar, Y., Escudier, M. P., Sanderson, J. D., Wade, W. G. & Prescott, N. J., Aug 2019, In: Inflammatory Bowel Diseases. 25, 8, p. 1367-1374 8 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1101/422865, https://doi.org/10.1093/ibd/izz022
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Taylor, K. M., Hanscombe, K. B., Prescott, N. J., Iniesta, R., Traylor, M., Taylor, N. S., Fong, S., Powell, N., Irving, P. M., Anderson, S. H., Mathew, C. G., Lewis, C. M. & Sanderson, J. D., 14 Jun 2019, (E-pub ahead of print) In: Clinical Gastroenterology and Hepatology : the official clinical practice journal of the American Gastroenterological Association. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.cgh.2019.05.061
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Chen, W. C., Bye, H., Matejcic, M., Amar, A., Govender, D., Khew, Y. W., Beynon, V., Kerr, R., Singh, E., Prescott, N. J., Lewis, C. M., Babb de Villiers, C., Parker, M. I. & Mathew, C. G., Apr 2019, In: Carcinogenesis. 40, 4, p. 513-520 8 p., bgz026. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1093/carcin/bgz026
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Traylor, M., Walker, J. L., Corrigan, A. A., Hernandez, M. A., Newhouse, S. J., Folarin, A. A., Patel, H., Ross, P. J., Sanderson, J. D., Spicer, J., Prescott, N. J., Mathew, C. G., Marinaki, A. M. & Lewis, C. M., 1 May 2018, In: PLoS ONE. 13, 5, 11 p., e0188911. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1371/journal.pone.0188911
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Onoufriadis, A., Stone, K., Katsiamides, A., Amar, A., Omar, Y., de Lange, K. M., Taylor, K., Barrett, J. C., Pollok, R., Hayee, BH., Mansfield, J. C., Sanderson, J. D., Simpson, M. A., Mathew, C. G. & Prescott, N. J., Mar 2018, In: Journal of Crohn's & colitis. 12, 3, p. 321–326 Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1101/182113, https://doi.org/10.1093/ecco-jcc/jjx157
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Reynolds, J. J., Bicknell, L. S., Carroll, P., Higgs, M. R., Shaheen, R., Murray, J. E., Papadopoulos, D. K., Leitch, A., Murina, O., Tarnauskaitė, Ž., Wessel, S. R., Zlatanou, A., Vernet, A., von Kriegsheim, A., Mottram, R. M. A., Logan, C. V., Bye, H., Li, Y., Brean, A., Maddirevula, S. & 42 others, Challis, R. C., Skouloudaki, K., Almoisheer, A., Alsaif, H. S., Amar, A., Prescott, N. J., Bober, M. B., Duker, A., Faqeih, E., Seidahmed, M. Z., Al Tala, S., Alswaid, A., Ahmed, S., Al-Aama, J. Y., Altmüller, J., Al Balwi, M., Brady, A. F., Chessa, L., Cox, H., Fischetto, R., Heller, R., Henderson, B. D., Hobson, E., Nürnberg, P., Percin, E. F., Peron, A., Spaccini, L., Quigley, A. J., Thakur, S., Wise, C. A., Yoon, G., Alnemer, M., Tomancak, P., Yigit, G., Taylor, A. M. R., Reijns, M. A. M., Simpson, M. A., Cortez, D., Alkuraya, F. S., Mathew, C. G., Jackson, A. P. & Stewart, G. S., 1 Apr 2017, In: Nature Genetics. 49, 4, p. 537-549 Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/ng.3790