Dr Nicholas Ashton Researchers Postdoctoral Research Associate Contact details nicholas.j.ashton@kcl.ac.uk
Plasma Cystatin C Correlates with Plasma NfL Levels and Predicts Disease Progression in Parkinson's Disease Imarisio, A., Pilotto, A., Garrafa, E., Conforti, F., Masciocchi, S., Turrone, R., Gipponi, S., Cottini, E., Rizzetti, M. C., Porrini, V., Gussago, C., Pizzi, M., Guadagni, F., Zetterberg, H., Ashton, N. J., Hye, A. & Padovani, A., 1 Jul 2022, In: Neurodegenerative Diseases. 21, 5-6, p. 109-116 8 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1159/000523982 Association of Plasma p-tau181 and p-tau231 Concentrations with Cognitive Decline in Patients with Probable Dementia with Lewy Bodies Gonzalez, M. C., Ashton, N. J., Gomes, B. F., Tovar-Rios, D. A., Blanc, F., Karikari, T. K., Mollenhauer, B., Pilotto, A., Lemstra, A., Paquet, C., Abdelnour, C., Kramberger, M. G., Bonanni, L., Vandenberghe, R., Hye, A., Blennow, K., Zetterberg, H. & Aarsland, D., 2022, In: JAMA Neurology. 79, 1, p. 32-37 6 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1001/jamaneurol.2021.4222 A genome-wide association study of plasma phosphorylated tau181 Lord, J., Zettergren, A., Ashton, N., Karkari, T., Benedet, A., Simren, J., Hye, A., Aarsland, D., Zetterberg, H., Blennow, K. & Proitsi, P., Oct 2021, In: Neurobiology of Aging. 106, p. 304.e1-304.e3 Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/S0197-4580(21)00134-2, https://doi.org/10.1016/j.neurobiolaging.2021.04.018 A multicentre validation study of the diagnostic value of plasma neurofilament light Ashton, N. J., Janelidze, S., Al Khleifat, A., Leuzy, A., van der Ende, E. L., Karikari, T. K., Benedet, A. L., Pascoal, T. A., Lleó, A., Parnetti, L., Galimberti, D., Bonanni, L., Pilotto, A., Padovani, A., Lycke, J., Novakova, L., Axelsson, M., Velayudhan, L., Rabinovici, G. D., Miller, B., & 21 othersPariante, C., Nikkheslat, N., Resnick, S. M., Thambisetty, M., Schöll, M., Fernández-Eulate, G., Gil-Bea, F. J., López de Munain, A., Al-Chalabi, A., Rosa-Neto, P., Strydom, A., Svenningsson, P., Stomrud, E., Santillo, A., Aarsland, D., van Swieten, J. C., Palmqvist, S., Zetterberg, H., Blennow, K., Hye, A. & Hansson, O., 7 Jun 2021, In: Nature Communications. 12, 1, 3400. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41467-021-23620-z Novel tau biomarkers phosphorylated at T181, T217 or T231 rise in the initial stages of the preclinical Alzheimer’s continuum when only subtle changes in Aβ pathology are detected for the ALFA Study, 7 Dec 2020, In: EMBO Molecular Medicine. 12, 12, e12921. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.15252/emmm.202012921 Plasma NfL, clinical subtypes and motor progression in Parkinson's disease Pilotto, A., Imarisio, A., Conforti, F., Scalvini, A., Masciocchi, S., Nocivelli, S., Turrone, R., Gipponi, S., Cottini, E., Borroni, B., Rizzetti, M. C., Pizzi, M., Bonanni, L., Sturchio, A., Espay, A. J., Zetterberg, H., Ashton, N. J., Hye, A. & Padovani, A., Jun 2021, In: Parkinsonism and Related Disorders. 87, p. 41-47 7 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.parkreldis.2021.04.016 Replication study of plasma proteins relating to Alzheimer's pathology Shi, L., Winchester, L. M., Westwood, S., Baird, A. L., Anand, S. N., Buckley, N. J., Hye, A., Ashton, N. J., Bos, I., Vos, S. J. B., Kate, M. T., Scheltens, P., Teunissen, C. E., Vandenberghe, R., Gabel, S., Meersmans, K., Engelborghs, S., De Roeck, E. E., Sleegers, K., Frisoni, G. B., & 32 othersBlin, O., Richardson, J. C., Bordet, R., Molinuevo, J. L., Rami, L., Wallin, A., Kettunen, P., Tsolaki, M., Verhey, F., Lléo, A., Sala, I., Popp, J., Peyratout, G., Martinez-Lage, P., Tainta, M., Johannsen, P., Freund-Levi, Y., Frölich, L., Dobricic, V., Legido-Quigley, C., Barkhof, F., Andreasson, U., Blennow, K., Zetterberg, H., Streffer, J., Lill, C. M., Bertram, L., Visser, P. J., Kolb, H. C., Narayan, V. A., Lovestone, S. & Nevado-Holgado, A. J., Sep 2021, In: Alzheimer's and Dementia. 17, 9, p. 1452-1464 13 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1002/alz.12322 The diagnostic and prognostic capabilities of plasma biomarkers in Alzheimer's disease for the AddNeuroMed consortium, Jul 2021, In: Alzheimer's and Dementia. 17, 7, p. 1145-1156 12 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1002/alz.12283 Dickkopf-1 Overexpression in vitro Nominates Candidate Blood Biomarkers Relating to Alzheimer's Disease Pathology Shi, L., Winchester, L. M., Liu, B. Y., Killick, R., Ribe, E. M., Westwood, S., Baird, A. L., Buckley, N. J., Hong, S., Dobricic, V., Kilpert, F., Franke, A., Kiddle, S., Sattlecker, M., Dobson, R., Cuadrado, A., Hye, A., Ashton, N. J., Morgan, A. R., Bos, I., & 47 othersVos, S. J. B., Ten Kate, M., Scheltens, P., Vandenberghe, R., Gabel, S., Meersmans, K., Engelborghs, S., De Roeck, E. E., Sleegers, K., Frisoni, G. B., Blin, O., Richardson, J. C., Bordet, R., Molinuevo, J. L., Rami, L., Wallin, A., Kettunen, P., Tsolaki, M., Verhey, F., Lleó, A., Alcolea, D., Popp, J., Peyratout, G., Martinez-Lage, P., Tainta, M., Johannsen, P., Teunissen, C. E., Freund-Levi, Y., Frölich, L., Legido-Quigley, C., Barkhof, F., Blennow, K., Rasmussen, K. L., Nordestgaard, B. G., Frikke-Schmidt, R., Nielsen, S. F., Soininen, H., Vellas, B., Kloszewska, I., Mecocci, P., Zetterberg, H., Morgan, B. P., Streffer, J., Visser, P. J., Bertram, L., Nevado-Holgado, A. J. & Lovestone, S., 2020, In: Journal of Alzheimer's Disease. 77, 3, p. 1353-1368 16 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.3233/JAD-200208 Serum Hepcidin Levels in Cognitively Normal Older Adults with High Neocortical Amyloid-β Load Chatterjee, P., Mohammadi, M., Goozee, K., Shah, T. M., Sohrabi, H. R., Dias, C. B., Shen, K., Asih, P. R., Dave, P., Pedrini, S., Ashton, N. J., Hye, A., Taddei, K., Lovejoy, D. B., Zetterberg, H., Blennow, K. & Martins, R. N., 1 Jan 2020, In: Journal of Alzheimer's disease : JAD. 76, 1, p. 291-301 11 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.3233/JAD-200162 View all publications