Nick Massouh is a postgraduate (PhD) student in the Department of Chemistry at King’s College London. He completed his BSc in Biomedical Sciences at the University of Kent (UKC) in 2020, where his final-year project focused on myosin kinetics in cardiac and skeletal muscle tissue. He then joined the Mulligan Lab at UKC to undertake an MRes, during which he explored the structure and binding activity of members of the tripartite ATP-independent periplasmic (TRAP) membrane transporter family in bacteria and archaea.

Following his studies, Nick moved into industry, holding R&D roles at leading UK biotechnology companies, including LabGenius Therapeutics, where he gained experience in machine-learning-guided antibody engineering, and Engitix Therapeutics, where he contributed to drug profiling and target validation campaigns in fibrosis and oncology.

In 2024, Nick returned to academia to begin a PhD under the supervision of Dr Robert Jefferson. His project combines computational and wet-lab approaches to understand the determinants of peptide-mediated GPCR signalling.

Research Interests: 

• G protein-coupled receptors (GPCRs)
• Membrane protein biochemistry
• Computational biology
• Structural biology
• Drug discovery
• Human disease

Thesis Title:

Determinants of Peptide-Mediated GPCR Signalling

PhD Supervisor

Dr Robert Jefferson & Professor Paula Booth