
Professor Philip Chowienczyk
Professor of Clinical Cardiovascular Pharmacology
Research interests
- Cardiovascular
Contact details
Biography
Philip Chowienczyk is a Professor of Clinical Cardiovascular Pharmacology in the School of Cardiovascular Medicine & Sciences.
Serum metabolomics improves risk stratification for incident heart failure
Oexner, R. R., Ahn, H., Theofilatos, K., Shah, R. A., Schmitt, R., Chowienczyk, P., Zoccarato, A. & Shah, A. M., Apr 2024, In: EUROPEAN JOURNAL OF HEART FAILURE. 26, 4, p. 829-840 12 p.Research output: Contribution to journal › Article › peer-review
Evidence on the cost-effectiveness of genetic-guided pharmacotherapy for venous thromboembolism: A systematic and critical literature review
Fox-Rushby, J., Lim, K. K. & Chowienczyk, P., 2021, In: PHARMACOGENOMICS.Research output: Contribution to journal › Article › peer-review
Determinants of recovery from post-COVID-19 dyspnoea: analysis of UK prospective cohorts of hospitalised COVID-19 patients and community-based controls
PHOSP-COVID Study Collaborative Group, Pfeffer, P. E., Abel, K., Ahmad, S., Ahmed, R., Ali, M., Allen, R. J., Almeida, P., Anderson, D., Armstrong, L., Armstrong, N., Ashworth, M., Ayoub, A., Baggott, R., Bailey, L., Baldwin, D., Ballard, C., Banerjee, A., Bates, A. & Begum, M. & 276 others, Bell, D., Bell, R., Berry, C., Bhui, K., Bramham, K., Breen, G., Brookes, C., Broome, M., Brown, A., Brown, J., Brown, J., Brown, M., Burns, A., Butt, A., Byrne, S., Carson, G., Carter, P., Chalder, T., Chambers, R. C., Chan, F., Chen, J., Cheng, Y., Chiribiri, A., Choudhury, N., Chowienczyk, P., Clark, D., Clark, C., Clarke, J., Cole, J., Coleman, C., Connolly, B., Connor, L., Cook, A., Cooper, B., Cooper, J., Cooper, S., Craig, T., Cross, A., David, A., Davies, E., Davies, G. A., Davies, G. A., Davies, K., Davies, M. J., Dawson, J., Donaldson, A., Dong, T., Dougherty, A., Dowling, R., drury, H. J. C., Dunn, S., Edwards, S., Elliott, A., Elliott, K., Evans, D., Evans, H., Evans, J., Evans, R., Evans, R., Evans, R., Evans, T., Finch, J., Fisher, H., Flynn, M., Ford, A., Francis, R., Fu, X., Gill, M., Goodwin, C., Gooptu, B., Gregory, H., Gregory, R., Grieve, D., Griffiths, L., Gupta, A., Hall, L., Harris, E., Harris, V. C., Harrison, P., Hart, N., Harvey, A., Harvey, M., Hayday, A., Henderson, M., Ho, L. P., Holden, S., Holland, M., Holmes, M., Hosseini, A., Hotopf, M., Howard, L. S., Hughes, A. D., Hughes, J., Hughes, R., Husain, M., Ismail, K., Jackson, T., Jacob, J., James, W. Y., Jenkins, R. G., Johnson, C., Johnson, S., Jolley, C. J., Jones, D., Jones, G., Jones, H., Jones, I., Jones, L., Jones, M. G., Jones, S., Jose, S., Kaltsakas, G., Kelly, S., Kerr, S., Khan, F., King, B., Knight, S., Kon, S., Kon, S., Laing, C., Lasserson, D., Lawson, C., Lee, D., Lee, J. H., Lewis, D., Lewis, J., Li, X., Lim, L., Lloyd, A., Lord, J. M., Major, E., Malim, M., D-C. Man, W., Mandal, S., Mangion, K., Marks, M., Marsh, S., Marshall, B., Marshall, M., Martin, J., Martinez, L. M., McMahon, M. J., Mehta, P., Miller, C., Mills, C., Mitchell, J., Mohamed, A., Mohammed, S., Morley, A., Morrow, A., Moss, A. J., Moss, P., Neal, A., Newby, D. E., Newman, J., Nicholson, T., O'Brien, C., Ostermann, M., Owen, J., Pariante, C., Parker, S., Patel, B., Patel, M., Patel, S., Payne, S., Pearce, L., Peng, Y., Pennington, C., Plant, H., Plein, S., Porter, J., Porter, J., Powell, N., Pratt, J., Price, A., Price, C., Price, D., Prickett, A., Quigley, J., Qureshi, I. N., Rahman, N. M., Reddy, A., Rees, M., Rees, T., Reynolds, W., Richards, A., Richardson, E., Richardson, M., Roberts, K., Robertson, E., Robinson, E., Robinson, L., Rodger, J., Ross, A., Rowe, A., Rowland, A., Rowland, J., Russell, R., Sage, E. K., Saunders, K., Saunders, R. M., Saunders, P., Scott, J. T., Shah, A., Shah, K., Shah, P., Shankar-Hari, M., Sharma, M., Sharpe, C., Shaw, A., Shaw, K., Simpson, J., Singh, C., Singh, S., Singh, S., Smith, A., Smith, D., Smith, S., Smith, J., Smith, L., Spencer, L. G., Stephenson, L., Stewart, I., Stockdale, S., Stone, R., Tan, A. L., Taylor, A., Taylor, C., Taylor, J., Terry, S., Thomas, C., Thomas, D. C., Thomas, S., Thomas, A. K., Thompson, T., Thompson, A. A. R., Tilley, J., Tomlinson, J., Turner, S., Turner, K., Wade, P., Wainwright, T., Walker, S., Walsh, J. A., Walsh, S., Ward, T. J. C., Watson, E., Watson, L., Watson, J., McCall, J. W., Welch, C., Wessely, S., West, S., White, S., Whitney, J., Whittaker, S., Wild, J., Williams, B., Williams, N., Williams, J., Willoughby, J., Wilson, A., Wilson, D., Wilson, I., Wood, C., Woods, J., Wright, C., Wright, L., Wright, S., Xu, M., Yip, K. P., Young, B., Young, S., Young, A., Zhao, B. & Zheng, B., Jun 2023, In: The Lancet Regional Health - Europe. 29, 100635.Research output: Contribution to journal › Article › peer-review
Accelarated immune ageing is associated with COVID-19 disease severity
on behalf of the PHOSP-COVID Study collaborative group, ISARIC4C Investigators, Abel, K., Ahmad, S., Ahmed, R., Ali, M., Allen, R. J., Almeida, P., Anderson, D., Armstrong, L., Armstrong, N., Ashworth, M., Ayoub, A., Baggott, R., Bailey, L., Baldwin, D., Ballard, C., Banerjee, A., Bates, A. & Begum, M. & 279 others, Bell, D., Bell, R., Berry, C., Bhui, K., Bramham, K., Breen, G., Brookes, C., Broome, M., Brown, A., Brown, A., Brown, J., Brown, J., Brown, J., Brown, M., Brown, M., Burns, A., Butt, A., Byrne, S., Carson, G., Carter, P., Chalder, T., CHambers, R. C., Chan, F., Chen, J., Cheng, Y., Chiribiri, A., Choudhury, N., Chowienczyk, P., Clark, D., Clark, C., Clarke, J., Cole, J., Coleman, C., Connolly, B., Connor, L., Cook, A., Cooper, B., Cooper, J., Cooper, S., Craig, T., Cross, A., David, A., Davies, E., Davies, G., Davies, G., Davies, K., Davies, M. J., Dawson, J., Donaldson, A., Dong, T., Dougherty, A., Dowling, R., Dunn, S., Edwards, S., Elliott, A., Elliott, K., Evans, D., Evans, H., Evans, J., Evans, R. I., Evans, R. I., Evans, T., Finch, J., Fisher, H., Flynn, M., Ford, A., Francis, R., Fu, X., Gill, M., Goodwin, C., Gooptu, B., Gregory, H., Gregory, R., Grieve, D., Griffiths, L., Gupta, A., Hall, L., Harris, E., Harris, V. C., Harrison, P., Hart, N., Harvey, A., Harvey, M., Hayday, A., Henderson, M., Ho, L. P., Holden, S., Holland, M., Holmes, M., Hosseini, A., Hotopf, M., Howard, L. S., Hughes, A. D., Hughes, J., Hughes, R., Husain, M., Ismail, K., Jackson, T., Jacob, J., James, W. Y., Jenkins, R. G., Johnson, C., Johnson, S., Jolley, C. J., Jones, D., Jones, G., Jones, H., Jones, H., Jones, I., Jones, L., Jones, M. G., Jones, S., Jose, S., Kaltsakas, G., Kelly, S., Kerr, S., Khan, F., King, B., Knight, S., Kon, S. S., Kon, S. S., Laing, C., Lasserson, D., Lawson, C., Lawson, C., Lee, D., Lee, J. H., Lewis, D., Lewis, J., Li, X., Lim, L., Lloyd, A., Major, E., Malim, M., Man, W. D. C., Mandal, S., Mangion, K., Marsh, S., Marshall, B., Marshall, M., Martin, J., Martinez, L. M., McMahon, M. J., Mehta, P., Miller, C., Mills, C., Mitchell, J., Mohamed, A., Mohammed, S., Morley, A., Morrow, A., Moss, A. J., Neal, A., Newby, D. E., Newman, J., Nicholson, T., Ostermann, M., Owen, J., Pariante, C., Parker, S., Patel, B., Patel, M., Patel, S., Payne, S., Pearce, L., Peng, Y., Pennington, C., Pfeffer, P., Plant, H., Plein, S., Porter, J. C., Porter, J., Powell, N., Pratt, J., Price, A., Price, C., Price, C., Price, D., Prickett, A., Quigley, J., Qureshi, I. N., Rahman, N. M., Reddy, A., Rees, M., Rees, T., Reynolds, W., Richards, A., Richardson, E., Richardson, M., Roberts, K., Robertson, E., Robinson, E., Robinson, L., Rodger, J., Ross, A., Rowe, A., Rowland, A., Rowland, J., Russell, R., Sage, E. K., Saunders, K., Saunders, R. M., Saunders, P., Scott, J. T., Shah, A., Shah, K., Shah, P., Shankar-Hari, M., Sharma, M., Sharpe, C., Shaw, A., Shaw, K., Simpson, J., Singh, C., Singh, S., Singh, S., Smith, A., Smith, D., Smith, S., Smith, J., Smith, L., Spencer, L. G., Stephenson, L., Stewart, I., Stockdale, S., Stone, R., Tan, A. L., Taylor, A., Taylor, C., Taylor, J., Terry, S., Thomas, C., Thomas, D. C., Thomas, S., Thomas, A. K., Thompson, T., Thompson, A. A. R., Tilley, J., Tomlinson, J., Turner, S., Turner, K., Wade, P., Wainwright, T., Walker, S., Walker, S., Walsh, J. A., Walsh, S., Ward, T. J. C., Watson, E., Watson, L., Watson, J., Weir McCall, J., Welch, C., Wessely, S., West, S., White, S., Whitney, J., Whittaker, S., Wild, J., Williams, B., Williams, N., Williams, N., Williams, J., Willoughby, J., Wilson, A., Wilson, D., Wilson, I., Wood, C., Woods, J., Wright, C., Wright, L., Wright, S., Xu, M., Yip, K. P., Young, B., Young, S., Young, A., Zhao, B. & Zheng, B., 11 Jan 2024, (E-pub ahead of print) In: Immunity and Ageing. 21, 1, 6.Research output: Contribution to journal › Article › peer-review
Genetic-guided pharmacotherapy for coronary artery disease: A systematic and critical review of economic evaluations
Fox-Rushby, J., Lim, K. K., Koleva-Kolarova, R. & Chowienczyk, P., 2024, In: American Heart Journal.Research output: Contribution to journal › Article › peer-review
Automated Quality Controlled Analysis of 2D Phase Contrast Cardiovascular Magnetic Resonance Imaging
Chan, E., O’Hanlon, C., Marquez, C. A., Petalcorin, M., Mariscal-Harana, J., Gu, H., Kim, R. J., Judd, R. M., Chowienczyk, P., Schnabel, J. A., Razavi, R., King, A. P., Ruijsink, B. & Puyol-Antón, E., 2022, Statistical Atlases and Computational Models of the Heart. Regular and CMRxMotion Challenge Papers - 13th International Workshop, STACOM 2022, Held in Conjunction with MICCAI 2022, Revised Selected Papers. Camara, O., Puyol-Antón, E., Suinesiaputra, A., Young, A., Qin, C., Sermesant, M. & Wang, S. (eds.). Springer Science and Business Media Deutschland GmbH, p. 101-111 11 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 13593 LNCS).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
Influence of Blood Pressure Reduction on Pulse Wave Velocity in Primary Hypertension: A Meta-Analysis and Comparison With an Acute Modulation of Transmural Pressure
McNally, R. J., Boguslavskyi, A., Malek, R., Floyd, C. N., Cecelja, M., Douiri, A., Bruno, R.-M., Farukh, B., Chowienczyk, P. & Faconti, L., 1 Jul 2024, In: Hypertension (Dallas, Tex. : 1979). 81, 7, p. 1619-1627 9 p.Research output: Contribution to journal › Article › peer-review
Ethnicity differences in geometric remodelling and myocardial composition in hypertension unveiled by cardiovascular magnetic resonance
Georgiopoulos, G., Faconti, L., Mohamed, A. T., Figliozzi, S., Asher, C., Keehn, L., McNally, R., Alfakih, K., Vennin, S., Chiribiri, A., Lamata, P., Chowienczyk, P. & Masci, P.-G., 1 Jul 2024, In: European heart journal. Cardiovascular Imaging. 25, 7, p. 901-911 11 p.Research output: Contribution to journal › Article › peer-review
Aortic Distensibility Measured by Automated Analysis of Magnetic Resonance Imaging Predicts Adverse Cardiovascular Events in UK Biobank
Cecelja, M., Ruijsink, B., Puyol-Antón, E., Li, Y., Godwin, H., King, A. P., Razavi, R. & Chowienczyk, P., 2022, In: Journal of the American Heart Association. 11, 23, e026361.Research output: Contribution to journal › Article › peer-review
Hemodynamic Determinants of Elevated Blood Pressure and Hypertension in the Middle to Older-Age UK Population: A UK Biobank Imaging Study
Li, Y., Chan, E., Puyol-Antón, E., Ruijsink, B., Cecelja, M., King, A. P., Razavi, R. & Chowienczyk, P., Nov 2023, In: Hypertension. 80, 11, p. 2473-2484 12 p.Research output: Contribution to journal › Article › peer-review
Decline in Left Ventricular Early Systolic Function with Worsening Kidney Function in Children with Chronic Kidney Disease: Insights from the 4C and HOT-KID Studies
Gu, H., Azukaitis, K., Doyon, A., Erdem, S., Ranchin, B., Harambat, J., Lugani, F., Boguslavskyi, A., Cansick, J., Finlay, E., Gilbert, R., Kerecuk, L., Lunn, A., Maxwell, H., Morgan, H., Shenoy, M., Shroff, R., Subramaniam, P., Tizard, J. & Tse, Y. & 4 others, Simpson, J., Chowienczyk, P., Schaefer, F. & Sinha, M. D., 23 Nov 2023, In: Journal of The American Society of Echocardiography.Research output: Contribution to journal › Article › peer-review
Arterial Stiffness Can Be Modulated by Pressure-Independent Mechanisms in Hypertension
Faconti, L., Farukh, B., McNally, R., Webb, A. & Chowienczyk, P., 6 Aug 2019, In: Journal of the American Heart Association. 8, 15, p. e012601Research output: Contribution to journal › Article › peer-review
Post-exertional increase in first-phase ejection fraction in recreational marathon runners
Faconti, L., Parsons, I., Farukh, B., McNally, R., Nesti, L., Fang, L., Stacey, M., Hill, N., Woods, D. & Chowienczyk, P., 2020, In: JRSM cardiovascular disease. 9, p. 2048004020926366Research output: Contribution to journal › Article › peer-review
Differences in hypertension phenotypes between Africans and Europeans: role of environment
Faconti, L., McNally, R. J., Farukh, B., Adeyemi, O., Cruickshank, J. K., Wilkinson, I. B., Chowienczyk, P. J. & Ojji, D., Jul 2020, In: Journal of hypertension. 38, 7, p. 1278-1285 8 p.Research output: Contribution to journal › Article › peer-review
A review of the prescribing trend of thiazide-type and thiazide-like diuretics in hypertension: A UK perspective
McNally, R. J., Morselli, F., Farukh, B., Chowienczyk, P. J. & Faconti, L., Dec 2019, In: British Journal of Clinical Pharmacology. 85, 12, p. 2707-2713 7 p.Research output: Contribution to journal › Review article › peer-review
Impaired β 2 -adrenergic endothelium-dependent vasodilation in patients previously hospitalized with coronavirus disease 2019
Faconti, L., Farukh, B., McNally, R. J., Brett, S. & Chowienczyk, P. J., 1 Jun 2023, In: Journal of hypertension. 41, 6, p. 951-957 7 p.Research output: Contribution to journal › Article › peer-review
"Resistant hypertension, catecholamine excess, left ventricular hypertrophy and systolic dysfunction: hypertensive cardiomyopathy?"
Gould, A., Ambrosini, I., Masci, P.-G., Mcnally, R. J., Chowienczyk, P. J. & Faconti, L., Dec 2023, In: Journal of Human Hypertension. 37, 12, p. 1129-1130 2 p.Research output: Contribution to journal › Article › peer-review
Cardiac contractility is a key factor in determining pulse pressure and its peripheral amplification
Piccioli, F., Li, Y., Valiani, A., Caleffi, V., Chowienczyk, P. & Alastruey, J., 2023, In: Frontiers in Cardiovascular Medicine. 10, 1197842.Research output: Contribution to journal › Article › peer-review
Genetic-guided pharmacotherapy for venous thromboembolism: a systematic and critical review of economic evaluations
Lim, K. K., Koleva-Kolarova, R., Chowienczyk, P., Wolfe, C. D. A. & Fox-Rushby, J., Dec 2021, In: Pharmacogenomics Journal. 21, 6, p. 625-637Research output: Contribution to journal › Review article › peer-review
Genetic-Guided Pharmacotherapy for Atrial Fibrillation: A Systematic and Critical Review of Economic Evaluations
Kamil, A. A., Lim, K. K., Koleva-Kolarova, R., Chowienczyk, P., Wolfe, C. D. A. & Fox-Rushby, J., Mar 2022, In: Value in Health. 25, 3, p. 461-472Research output: Contribution to journal › Review article › peer-review
Effects of sleep disturbance on dyspnoea and impaired lung function following hospital admission due to COVID-19 in the UK: a prospective multicentre cohort study
PHOSP-COVID Study Collaborative Group, Chalder, T., Jolley, C. J., Shah, A. M., Man, W. D. C., Jackson, C., Stewart, I. D., Cunningham, P. S., Chalder, T., Harris, V. C., Ho, L. P., Howard, L. S., Jolley, C. J., Jones, M. G., Marks, M., Patel, B., Richardson, M., Rowlands, A. V., Saunders, R. M. & Scott, J. T. & 273 others, Shah, A. M., Singh, S. J., Man, W. D. C., Porter, J. C., Thompson, R., Evans, R., Jones, S. E., Rutter, M. K., Abel, K., Ahmad, S., Ahmed, R., Ali, M., Allen, R. J., Anderson, D., Armstrong, L., Armstrong, N., Ashworth, M., Ayoub, A., Baggott, R., Bailey, L., Baldwin, D., Ballard, C., Banerjee, A., Bates, A., Begum, M., Bell, D., Bell, R., Berry, C., Bhui, K., Bramham, K., Breen, G., Brookes, C., Broome, M., Brown, A., Brown, J., Brown, J., Brown, M., Burns, A., Butt, A., Byrne, S., Carson, G., Carter, P., Chambers, R. C., Chan, F., Chen, J., Cheng, Y., Chiribiri, A., Choudhury, N., Chowienczyk, P., Clark, D., Clark, C., Clarke, J., Cole, J., Connolly, B., Connor, L., Cook, A., Cooper, B., Cooper, J., Cooper, S., Craig, T., David, A., Davies, E., Davies, G., Davies, G., Davies, K., Davies, M. J., Dawson, J., Donaldson, A., Dong, T., Dougherty, A., Dowling, R., Dunn, S., Edwards, S., Elliott, A., Elliott, K., Evans, D., Evans, H., Evans, J., Evans, R., Evans, R., Evans, T., Finch, J., Fisher, H., Flynn, M., Ford, A., Francis, R., Gill, M., Goodwin, C., Gooptu, B., Gregory, H., Gregory, R., Grieve, D., Griffiths, L., Gupta, A., Hall, L., Harris, E., Harrison, P., Hart, N., Harvey, A., Harvey, M., Hayday, A., Henderson, M., Holden, S., Holland, M., Holmes, M., Hosseini, A., Hotopf, M., Hughes, A. D., Hughes, J., Hughes, R., Husain, M., Ismail, K., Jackson, T., Jacob, J., James, W. Y., Jenkins, R. G., Johnson, C., Johnson, S., Jones, D., Jones, G., Jones, H., Jones, I., Jones, L., Jones, S., Jose, S., Kaltsakas, G., Kelly, S., Kerr, S., Khan, F., King, B., Knight, S., Kon, S., Kon, S., Laing, C., Lasserson, D., Lawson, C., Lee, D., Lee, J. H., Lewis, D., Lewis, J., Li, X., Lim, L., Lloyd, A., Lord, J. M., Major, E., Malim, M., Mandal, S., Mangion, K., Marsh, S., Marshall, B., Marshall, M., Martin, J., Martinez, L. M., McMahon, M. J., Mehta, P., Miller, C., Mills, C., Mitchell, J., Mohamed, A., Mohammed, S., Morley, A., Morrow, A., Moss, A. J., Moss, P., Neal, A., Newby, D. E., Newman, J., Nicholson, T., O'Brien, C., Ostermann, M., Owen, J., Pariante, C., Parker, S., Patel, M., Patel, S., Payne, S., Pearce, L., Peng, Y., Pennington, C., Pfeffer, P., Plant, H., Plein, S., Porter, J., Powell, N., Pratt, J., Price, A., Price, C., Price, D., Prickett, A., Quigley, J., Qureshi, I. N., Rahman, N. M., Rees, M., Reynolds, W., Richards, A., Richardson, E., Roberts, K., Robertson, E., Robinson, E., Robinson, L., Rodger, J., Ross, A., Rowe, A., Rowland, A., Rowland, J., Russell, R., Sage, E. K., Saunders, K., Saunders, P., Shah, K., Shah, P., Shankar-Hari, M., Sharma, M., Sharpe, C., Shaw, A., Shaw, K., Simpson, J., Singh, C., Smith, A., Smith, D., Smith, S., Smith, J., Smith, L., Spencer, L. G., Stephenson, L., Stone, R., Tan, A. L., Taylor, A., Taylor, C., Taylor, J., Terry, S., Thomas, C., Thomas, D. C., Thomas, S., Thomas, A. K., Thompson, T., Thompson, A. A. R., Tilley, J., Tomlinson, J., Turner, S., Turner, K., Wade, P., Wainwright, T., Walker, S., Walsh, J. A., Walsh, S., Ward, T. J. C., Watson, E., Watson, L., Watson, J., Wessely, S., West, S., White, S., Whitney, J., Whittaker, S., Wild, J. M., Williams, B., Williams, N., Williams, J., Willoughby, J., Wilson, A., Wilson, D., Wood, C., Woods, J., Wright, C., Wright, L., Wright, S., Xu, M., Yip, K. P., Young, B., Young, S., Young, A. & Zhao, B., Aug 2023, In: The Lancet Respiratory Medicine. 11, 8, p. 673-684 12 p.Research output: Contribution to journal › Article › peer-review
Correction to: Histamine, mast cell tryptase and post-exercise hypotension in healthy and collapsed marathon runners
Parsons, I. T., Stacey, M. J., Faconti, L., Hill, N., O'Hara, J., Walter, E., Farukh, B., McNally, R., Sharp, H., Patten, A., Grimaldi, R., Gall, N., Chowienczyk, P. & Woods, D. R., Nov 2021, In: European Journal of Applied Physiology. 121, 11, p. 3257-3258 2 p.Research output: Contribution to journal › Article › peer-review
Intensive compared with less intensive blood pressure control to prevent adverse cardiac remodelling in children with chronic kidney disease (HOT-KID): a parallel-group, open-label, multicentre, randomised, controlled trial
Sinha, M. D., Gu, H., Douiri, A., Cansick, J., Finlay, E., Gilbert, R., Kerecuk, L., Lunn, A., Maxwell, H., Morgan, H., Shenoy, M., Shroff, R., Subramaniam, P., Tizard, J., Tse, Y., Rezavi, R., Simpson, J. M. & Chowienczyk, P. J., 4 Jan 2023, In: The Lancet Child & Adolescent Health. 7, 1, p. 26-36 11 p.Research output: Contribution to journal › Article › peer-review
RELATION OF PULSE WAVE VELOCITY TO CONTEMPORANEOUS AND HISTORICAL BLOOD PRESSURE IN FEMALE TWINS: Arterial Stiffness and Blood Pressure
Keehn, L., Mangino, M., Spector, T., Chowienczyk, P. & Cecelja, M., 1 Feb 2023, In: Hypertension. 80, 2, p. 361-369 9 p.Research output: Contribution to journal › Article › peer-review
Postprandial Responses to a Standardised Meal in Hypertension: The Mediatory Role of Visceral Fat Mass
Louca, B., Berry, S., Bermingham, K., Franks, P. W., Wolf, J., Spector, T., Valdes, A. M., Chowienczyk, P. & Menni, C., Nov 2022, In: Nutrients. 14, 21, p. 4499 4499.Research output: Contribution to journal › Article › peer-review
Lifestyle intervention in obese pregnancy and cardiac remodelling in 3-year olds: children of the UPBEAT RCT
UPBEAT Consortium, Dec 2022, In: International Journal of Obesity. 46, 12, p. 2145-2155 11 p.Research output: Contribution to journal › Article › peer-review
Reproducibility of sequential ambulatory blood pressure and pulse wave velocity measurements in normotensive and hypertensive individuals
Keehn, L., Hall, W., Berry, S., Sanders, T., Floyd, C. & Chowienczyk, P., 1 Dec 2022, In: Journal of hypertension. 40, 12, p. 2528-2537 10 p.Research output: Contribution to journal › Article › peer-review
AI-Enabled Assessment of Cardiac Systolic and Diastolic Function from Echocardiography
Puyol-Antón, E., Ruijsink, B., Sidhu, B. S., Gould, J., Porter, B., Elliott, M. K., Mehta, V., Gu, H., Rinaldi, C. A., cowie, M., Chowienczyk, P., Razavi, R. & King, A. P., 15 Sept 2022, Simplifying Medical Ultrasound - 3rd International Workshop, ASMUS 2022, held in Conjunction with MICCAI 2022, Proceedings. Aylward, S., Noble, J. A., Hu, Y., Lee, S.-L., Baum, Z. & Min, Z. (eds.). Springer Science and Business Media Deutschland GmbH, p. 75-85 11 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 13565 LNCS).Research output: Chapter in Book/Report/Conference proceeding › Conference paper › peer-review
A meta-analysis of the haemodynamics of primary hypertension in children and adults
Li, Y., Haseler, E., McNally, R., Sinha, M. & Chowienczyk, P., 1 Feb 2023, In: Journal of Hypertension. 41, 2, p. 212-219 8 p.Research output: Contribution to journal › Review article › peer-review
The hypertension optimal treatment in children with chronic kidney disease (HOT-KID study): a randomised trial to compare intensive versus standard blood pressure targets on target organ damage in childhood CKD
Sinha, M., Gu, H., Douiri, A., Rezavi, R., Simpson, J. & Chowienczyk, P., Sept 2022, In: Journal of Human Hypertension. 36, SUPPL 1, p. 8-8Research output: Contribution to journal › Meeting Abstract › peer-review
IMPAIRED BETA-2ADRENERGIC ENDOTHELIUM-DEPENDENT VASODILATION IS REVERSED BY PHOSPHODIESTERASE INHIBITION IN PATIENTS PREVIOUSLY HOSPITALIZED WITH COVID-19
Faconti, L., Farukh, B., McNally, R., Brett, S. & Chowienczyk, P., 1 Jun 2022, In: Journal of hypertension. 40, p. e172Research output: Contribution to journal › Poster abstract › peer-review
Sensitivity and reproducibility of inferior vena cava diameter and superior vena cava flow velocity measurements to changes in cardiac preload in subjects with hypertension
Mcnally, R. J., Farukh, B., Chowienczyk, P. J. & Faconti, L., 1 Jan 2022, In: Journal of Cardiovascular Echography. 32, 1, p. 6-11 6 p.Research output: Contribution to journal › Article › peer-review
The effect of water temperature on orthostatic tolerance: a randomised crossover trial
Parsons, I. T., Hockin, B. C. D., Taha, O. M., Heeney, N. D., Williams, E. L., Lucci, V. E. M., Lee, R. H. Y., Stacey, M. J., Gall, N., Chowienczyk, P., Woods, D. R. & Claydon, V. E., Apr 2022, In: Clinical Autonomic Research. 32, 2, p. 131-141 11 p.Research output: Contribution to journal › Article › peer-review
A pilot study to evaluate the erythrocyte glycocalyx sensitivity to sodium as a marker for cellular salt sensitivity in hypertension
McNally, R. J., Morselli, F., Farukh, B., Chowienczyk, P. J. & Faconti, L., 12 Apr 2022, In: Journal of Human Hypertension.Research output: Contribution to journal › Article › peer-review
Neuronal nitric oxide synthase regulates regional brain perfusion in healthy humans
O'gallagher, K., Puledda, F., O'daly, O., Ryan, M., Dancy, L., Chowienczyk, P. J., Zelaya, F., Goadsby, P. J. & Shah, A. M., 1 Apr 2022, In: Cardiovascular Research. 118, 5, p. 1321-1329 9 p.Research output: Contribution to journal › Article › peer-review
Fairness in Cardiac Magnetic Resonance Imaging: Assessing Sex and Racial Bias in Deep Learning-based Segmentation
Puyol-Anton, E., Ruijsink, B., Mariscal Harana, J., Piechnik, S. K., Neubauer, S., Petersen, S. E., Razavi, R., Chowienczyk, P. & King, A. P., 7 Apr 2022, In: Frontiers in Cardiovascular Medicine. 9, 859310.Research output: Contribution to journal › Article › peer-review
Wearable Photoplethysmography for Cardiovascular Monitoring
Charlton, P., Kyriacou, P., Mant, J., Marozas, V., Chowienczyk, P. & Alastruey, J., 11 Mar 2022, In: Proceedings of the IEEE. 110, 3, p. 355-381 27 p.Research output: Contribution to journal › Article › peer-review
Effect of diuretics on plasma aldosterone and potassium in primary hypertension: A systematic review and meta-analysis
McNally, R. J., Farukh, B., Chowienczyk, P. J. & Faconti, L., 11 Apr 2022, In: British Journal of Clinical Pharmacology. 88, 5, p. 1964-1977 14 p.Research output: Contribution to journal › Review article › peer-review
Genetic-Guided Pharmacotherapy for Atrial Fibrillation: A Systematic and Critical Review of Economic Evaluations
Kamil, A. A., Lim, K. K., Koleva-Kolarova, R., Chowienczyk, P., Wolfe, C. D. A. & Fox-Rushby, J., 2 Dec 2021, (E-pub ahead of print) In: Value in Health. 25, 3Research output: Contribution to journal › Article › peer-review
Cardiovascular health and risk of hospitalization with COVID-19: a Mendelian Randomization study
Cecelja, M., Lewis, C. M., Shah, A. M. & Chowienczyk, P., 19 Nov 2021, (E-pub ahead of print) In: JRSM cardiovascular disease. 10Research output: Contribution to journal › Article › peer-review
Novel Pressure Wave Separation Analysis for Cardiovascular Function Assessment Highlights Major Role of Aortic Root
Vennin, S., Li, Y., Mariscal Harana, J., Charlton, P., Fok, H., Gu, H., Chowienczyk, P. & Alastruey, J., 12 Nov 2021, (E-pub ahead of print) In: IEEE Transactions on Biomedical Engineering. PPResearch output: Contribution to journal › Article › peer-review
First phase ejection fraction in aortic stenosis: A useful new measure of early left ventricular systolic dysfunction
Saeed, S., Gu, H., Rajani, R., Chowienczyk, P. & Chambers, J. B., 1 Nov 2021, In: Journal of Clinical Ultrasound. 49, 9, p. 932-935 4 p.Research output: Contribution to journal › Article › peer-review
Genetic-guided pharmacotherapy for venous thromboembolism: a systematic and critical review of economic evaluations
Lim, K. K., Koleva-Kolarova, R., Chowienczyk, P., Wolfe, C. D. A. & Fox-Rushby, J., Dec 2021, In: Pharmacogenomics Journal. 21, 6, p. 625-637 13 p.Research output: Contribution to journal › Review article › peer-review
First-phase ejection fraction by cardiovascular magnetic resonance predicts outcomes in aortic stenosis
Gu, H., Bing, R., Chin, C., Fang, L., White, A. C., Everett, R., Spath, N., Park, E., Chambers, J. B., Newby, D. E., Chiribiri, A., Dweck, M. R. & Chowienczyk, P., 10 Jun 2021, In: Journal of Cardiovascular Magnetic Resonance. 23, 1, p. 73 73.Research output: Contribution to journal › Article › peer-review
Direct cardiac versus systemic effects of inorganic nitrite on human left ventricular function: Effect of inorganic nitrite on LV function
O'Gallagher, K., Shah, A., Ryan, M., Roomi, A., Gu, H., Chowienczyk, P., Webb, A. & Kevin, O., 2021, (Accepted/In press) In: American Journal of Physiology.Research output: Contribution to journal › Article › peer-review
Impact of arterio-ventricular interaction on first-phase ejection fraction in aortic stenosis
Einarsen, E., Hjertaas, J. J., Gu, H., Matre, K., Chowienczyk, P. J., Gerdts, E., Chambers, J. B. & Saeed, S., 1 Jun 2021, In: European heart journal. Cardiovascular Imaging. 22, 6, p. 650-657 8 p.Research output: Contribution to journal › Article › peer-review
Estimating pulse wave velocity from the radial pressure wave using machine learning algorithms
Jin, W., Chowienczyk, P. & Alastruey, J., Jun 2021, In: PLoS ONE. 16, 6 June, p. e0245026 e0245026.Research output: Contribution to journal › Article › peer-review
The physiological effects of cardiac resynchronization therapy on aortic and pulmonary flow and dynamic and static components of systemic impedance
Sidhu, B., Claridge, S., Gu, H., Li, Y., Gould, J., Porter, B., Elliott, M., Mehta, V., Jackson, T., Patterson, T., Briceno, N., Lee, J., Redwood, S., Adhya, S., Niederer, S., Chowienczyk, P. & Rinaldi, C. A., 25 May 2021, (Accepted/In press) In: Heart rhythm : the official journal of the Heart Rhythm Society.Research output: Contribution to journal › Article › peer-review
Central aortic blood pressure from ultrasound wall-tracking of the carotid artery in children: Comparison with invasive measurements and radial tonometry
Milne, L., Keehn, L., Guilcher, A., Reidy, J. F., Karunanithy, N., Rosenthal, E., Qureshi, S., Chowienczyk, P. J. & Sinha, M. D., 21 May 2015, In: Hypertension. 65, 5, p. 1141-1146 6 p.Research output: Contribution to journal › Article › peer-review
Dietary nitrate prevents progression of carotid subclinical atherosclerosis through blood pressure-independent mechanisms in patients with or at risk of type 2 diabetes mellitus
Morselli, F., Faconti, L., Mills, C. E., Morant, S., Chowienczyk, P. J., Yeung, J. A., Cavarape, A., Cruickshank, J. K. & Webb, A. J., Dec 2021, In: British Journal of Clinical Pharmacology. 87, 12, p. 4726-4736 11 p.Research output: Contribution to journal › Article › peer-review
Research

Centre for Ageing Resilience In a Changing Environment - CARICE
Welcome to the Centre for Ageing Resilience in a Changing Environment: CARICE
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Lower blood pressure reduces cardiovascular disease for children with chronic kidney disease
The HOT-KID clinical trial looked at how lowering blood pressure in children with chronic kidney disease could prevent cardiac remodelling and associated...

Paper by King's researchers makes Readers' Choice List 2021
The article was selected as one of The Pharmacogenomics Journal’s 15 most cited or shared articles in 2021.

Researchers reveal that first-phase ejection fraction is associated with increased mortality in patients with COVID-19
Researchers reveal that first-phase ejection fraction is associated with increased mortality in patients with COVID-19

Serum metabolomics improves risk stratification for incident heart failure
Oexner, R. R., Ahn, H., Theofilatos, K., Shah, R. A., Schmitt, R., Chowienczyk, P., Zoccarato, A. & Shah, A. M., Apr 2024, In: EUROPEAN JOURNAL OF HEART FAILURE. 26, 4, p. 829-840 12 p.Research output: Contribution to journal › Article › peer-review
Evidence on the cost-effectiveness of genetic-guided pharmacotherapy for venous thromboembolism: A systematic and critical literature review
Fox-Rushby, J., Lim, K. K. & Chowienczyk, P., 2021, In: PHARMACOGENOMICS.Research output: Contribution to journal › Article › peer-review
Determinants of recovery from post-COVID-19 dyspnoea: analysis of UK prospective cohorts of hospitalised COVID-19 patients and community-based controls
PHOSP-COVID Study Collaborative Group, Pfeffer, P. E., Abel, K., Ahmad, S., Ahmed, R., Ali, M., Allen, R. J., Almeida, P., Anderson, D., Armstrong, L., Armstrong, N., Ashworth, M., Ayoub, A., Baggott, R., Bailey, L., Baldwin, D., Ballard, C., Banerjee, A., Bates, A. & Begum, M. & 276 others, Bell, D., Bell, R., Berry, C., Bhui, K., Bramham, K., Breen, G., Brookes, C., Broome, M., Brown, A., Brown, J., Brown, J., Brown, M., Burns, A., Butt, A., Byrne, S., Carson, G., Carter, P., Chalder, T., Chambers, R. C., Chan, F., Chen, J., Cheng, Y., Chiribiri, A., Choudhury, N., Chowienczyk, P., Clark, D., Clark, C., Clarke, J., Cole, J., Coleman, C., Connolly, B., Connor, L., Cook, A., Cooper, B., Cooper, J., Cooper, S., Craig, T., Cross, A., David, A., Davies, E., Davies, G. A., Davies, G. A., Davies, K., Davies, M. J., Dawson, J., Donaldson, A., Dong, T., Dougherty, A., Dowling, R., drury, H. J. C., Dunn, S., Edwards, S., Elliott, A., Elliott, K., Evans, D., Evans, H., Evans, J., Evans, R., Evans, R., Evans, R., Evans, T., Finch, J., Fisher, H., Flynn, M., Ford, A., Francis, R., Fu, X., Gill, M., Goodwin, C., Gooptu, B., Gregory, H., Gregory, R., Grieve, D., Griffiths, L., Gupta, A., Hall, L., Harris, E., Harris, V. C., Harrison, P., Hart, N., Harvey, A., Harvey, M., Hayday, A., Henderson, M., Ho, L. P., Holden, S., Holland, M., Holmes, M., Hosseini, A., Hotopf, M., Howard, L. S., Hughes, A. D., Hughes, J., Hughes, R., Husain, M., Ismail, K., Jackson, T., Jacob, J., James, W. Y., Jenkins, R. G., Johnson, C., Johnson, S., Jolley, C. J., Jones, D., Jones, G., Jones, H., Jones, I., Jones, L., Jones, M. G., Jones, S., Jose, S., Kaltsakas, G., Kelly, S., Kerr, S., Khan, F., King, B., Knight, S., Kon, S., Kon, S., Laing, C., Lasserson, D., Lawson, C., Lee, D., Lee, J. H., Lewis, D., Lewis, J., Li, X., Lim, L., Lloyd, A., Lord, J. M., Major, E., Malim, M., D-C. Man, W., Mandal, S., Mangion, K., Marks, M., Marsh, S., Marshall, B., Marshall, M., Martin, J., Martinez, L. M., McMahon, M. J., Mehta, P., Miller, C., Mills, C., Mitchell, J., Mohamed, A., Mohammed, S., Morley, A., Morrow, A., Moss, A. J., Moss, P., Neal, A., Newby, D. E., Newman, J., Nicholson, T., O'Brien, C., Ostermann, M., Owen, J., Pariante, C., Parker, S., Patel, B., Patel, M., Patel, S., Payne, S., Pearce, L., Peng, Y., Pennington, C., Plant, H., Plein, S., Porter, J., Porter, J., Powell, N., Pratt, J., Price, A., Price, C., Price, D., Prickett, A., Quigley, J., Qureshi, I. N., Rahman, N. M., Reddy, A., Rees, M., Rees, T., Reynolds, W., Richards, A., Richardson, E., Richardson, M., Roberts, K., Robertson, E., Robinson, E., Robinson, L., Rodger, J., Ross, A., Rowe, A., Rowland, A., Rowland, J., Russell, R., Sage, E. K., Saunders, K., Saunders, R. M., Saunders, P., Scott, J. T., Shah, A., Shah, K., Shah, P., Shankar-Hari, M., Sharma, M., Sharpe, C., Shaw, A., Shaw, K., Simpson, J., Singh, C., Singh, S., Singh, S., Smith, A., Smith, D., Smith, S., Smith, J., Smith, L., Spencer, L. G., Stephenson, L., Stewart, I., Stockdale, S., Stone, R., Tan, A. L., Taylor, A., Taylor, C., Taylor, J., Terry, S., Thomas, C., Thomas, D. C., Thomas, S., Thomas, A. K., Thompson, T., Thompson, A. A. R., Tilley, J., Tomlinson, J., Turner, S., Turner, K., Wade, P., Wainwright, T., Walker, S., Walsh, J. A., Walsh, S., Ward, T. J. C., Watson, E., Watson, L., Watson, J., McCall, J. W., Welch, C., Wessely, S., West, S., White, S., Whitney, J., Whittaker, S., Wild, J., Williams, B., Williams, N., Williams, J., Willoughby, J., Wilson, A., Wilson, D., Wilson, I., Wood, C., Woods, J., Wright, C., Wright, L., Wright, S., Xu, M., Yip, K. P., Young, B., Young, S., Young, A., Zhao, B. & Zheng, B., Jun 2023, In: The Lancet Regional Health - Europe. 29, 100635.Research output: Contribution to journal › Article › peer-review
Accelarated immune ageing is associated with COVID-19 disease severity
on behalf of the PHOSP-COVID Study collaborative group, ISARIC4C Investigators, Abel, K., Ahmad, S., Ahmed, R., Ali, M., Allen, R. J., Almeida, P., Anderson, D., Armstrong, L., Armstrong, N., Ashworth, M., Ayoub, A., Baggott, R., Bailey, L., Baldwin, D., Ballard, C., Banerjee, A., Bates, A. & Begum, M. & 279 others, Bell, D., Bell, R., Berry, C., Bhui, K., Bramham, K., Breen, G., Brookes, C., Broome, M., Brown, A., Brown, A., Brown, J., Brown, J., Brown, J., Brown, M., Brown, M., Burns, A., Butt, A., Byrne, S., Carson, G., Carter, P., Chalder, T., CHambers, R. C., Chan, F., Chen, J., Cheng, Y., Chiribiri, A., Choudhury, N., Chowienczyk, P., Clark, D., Clark, C., Clarke, J., Cole, J., Coleman, C., Connolly, B., Connor, L., Cook, A., Cooper, B., Cooper, J., Cooper, S., Craig, T., Cross, A., David, A., Davies, E., Davies, G., Davies, G., Davies, K., Davies, M. J., Dawson, J., Donaldson, A., Dong, T., Dougherty, A., Dowling, R., Dunn, S., Edwards, S., Elliott, A., Elliott, K., Evans, D., Evans, H., Evans, J., Evans, R. I., Evans, R. I., Evans, T., Finch, J., Fisher, H., Flynn, M., Ford, A., Francis, R., Fu, X., Gill, M., Goodwin, C., Gooptu, B., Gregory, H., Gregory, R., Grieve, D., Griffiths, L., Gupta, A., Hall, L., Harris, E., Harris, V. C., Harrison, P., Hart, N., Harvey, A., Harvey, M., Hayday, A., Henderson, M., Ho, L. P., Holden, S., Holland, M., Holmes, M., Hosseini, A., Hotopf, M., Howard, L. S., Hughes, A. D., Hughes, J., Hughes, R., Husain, M., Ismail, K., Jackson, T., Jacob, J., James, W. Y., Jenkins, R. G., Johnson, C., Johnson, S., Jolley, C. J., Jones, D., Jones, G., Jones, H., Jones, H., Jones, I., Jones, L., Jones, M. G., Jones, S., Jose, S., Kaltsakas, G., Kelly, S., Kerr, S., Khan, F., King, B., Knight, S., Kon, S. S., Kon, S. S., Laing, C., Lasserson, D., Lawson, C., Lawson, C., Lee, D., Lee, J. H., Lewis, D., Lewis, J., Li, X., Lim, L., Lloyd, A., Major, E., Malim, M., Man, W. D. C., Mandal, S., Mangion, K., Marsh, S., Marshall, B., Marshall, M., Martin, J., Martinez, L. M., McMahon, M. J., Mehta, P., Miller, C., Mills, C., Mitchell, J., Mohamed, A., Mohammed, S., Morley, A., Morrow, A., Moss, A. J., Neal, A., Newby, D. E., Newman, J., Nicholson, T., Ostermann, M., Owen, J., Pariante, C., Parker, S., Patel, B., Patel, M., Patel, S., Payne, S., Pearce, L., Peng, Y., Pennington, C., Pfeffer, P., Plant, H., Plein, S., Porter, J. C., Porter, J., Powell, N., Pratt, J., Price, A., Price, C., Price, C., Price, D., Prickett, A., Quigley, J., Qureshi, I. N., Rahman, N. M., Reddy, A., Rees, M., Rees, T., Reynolds, W., Richards, A., Richardson, E., Richardson, M., Roberts, K., Robertson, E., Robinson, E., Robinson, L., Rodger, J., Ross, A., Rowe, A., Rowland, A., Rowland, J., Russell, R., Sage, E. K., Saunders, K., Saunders, R. M., Saunders, P., Scott, J. T., Shah, A., Shah, K., Shah, P., Shankar-Hari, M., Sharma, M., Sharpe, C., Shaw, A., Shaw, K., Simpson, J., Singh, C., Singh, S., Singh, S., Smith, A., Smith, D., Smith, S., Smith, J., Smith, L., Spencer, L. G., Stephenson, L., Stewart, I., Stockdale, S., Stone, R., Tan, A. L., Taylor, A., Taylor, C., Taylor, J., Terry, S., Thomas, C., Thomas, D. C., Thomas, S., Thomas, A. K., Thompson, T., Thompson, A. A. R., Tilley, J., Tomlinson, J., Turner, S., Turner, K., Wade, P., Wainwright, T., Walker, S., Walker, S., Walsh, J. A., Walsh, S., Ward, T. J. C., Watson, E., Watson, L., Watson, J., Weir McCall, J., Welch, C., Wessely, S., West, S., White, S., Whitney, J., Whittaker, S., Wild, J., Williams, B., Williams, N., Williams, N., Williams, J., Willoughby, J., Wilson, A., Wilson, D., Wilson, I., Wood, C., Woods, J., Wright, C., Wright, L., Wright, S., Xu, M., Yip, K. P., Young, B., Young, S., Young, A., Zhao, B. & Zheng, B., 11 Jan 2024, (E-pub ahead of print) In: Immunity and Ageing. 21, 1, 6.Research output: Contribution to journal › Article › peer-review
Genetic-guided pharmacotherapy for coronary artery disease: A systematic and critical review of economic evaluations
Fox-Rushby, J., Lim, K. K., Koleva-Kolarova, R. & Chowienczyk, P., 2024, In: American Heart Journal.Research output: Contribution to journal › Article › peer-review
Automated Quality Controlled Analysis of 2D Phase Contrast Cardiovascular Magnetic Resonance Imaging
Chan, E., O’Hanlon, C., Marquez, C. A., Petalcorin, M., Mariscal-Harana, J., Gu, H., Kim, R. J., Judd, R. M., Chowienczyk, P., Schnabel, J. A., Razavi, R., King, A. P., Ruijsink, B. & Puyol-Antón, E., 2022, Statistical Atlases and Computational Models of the Heart. Regular and CMRxMotion Challenge Papers - 13th International Workshop, STACOM 2022, Held in Conjunction with MICCAI 2022, Revised Selected Papers. Camara, O., Puyol-Antón, E., Suinesiaputra, A., Young, A., Qin, C., Sermesant, M. & Wang, S. (eds.). Springer Science and Business Media Deutschland GmbH, p. 101-111 11 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 13593 LNCS).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
Influence of Blood Pressure Reduction on Pulse Wave Velocity in Primary Hypertension: A Meta-Analysis and Comparison With an Acute Modulation of Transmural Pressure
McNally, R. J., Boguslavskyi, A., Malek, R., Floyd, C. N., Cecelja, M., Douiri, A., Bruno, R.-M., Farukh, B., Chowienczyk, P. & Faconti, L., 1 Jul 2024, In: Hypertension (Dallas, Tex. : 1979). 81, 7, p. 1619-1627 9 p.Research output: Contribution to journal › Article › peer-review
Ethnicity differences in geometric remodelling and myocardial composition in hypertension unveiled by cardiovascular magnetic resonance
Georgiopoulos, G., Faconti, L., Mohamed, A. T., Figliozzi, S., Asher, C., Keehn, L., McNally, R., Alfakih, K., Vennin, S., Chiribiri, A., Lamata, P., Chowienczyk, P. & Masci, P.-G., 1 Jul 2024, In: European heart journal. Cardiovascular Imaging. 25, 7, p. 901-911 11 p.Research output: Contribution to journal › Article › peer-review
Aortic Distensibility Measured by Automated Analysis of Magnetic Resonance Imaging Predicts Adverse Cardiovascular Events in UK Biobank
Cecelja, M., Ruijsink, B., Puyol-Antón, E., Li, Y., Godwin, H., King, A. P., Razavi, R. & Chowienczyk, P., 2022, In: Journal of the American Heart Association. 11, 23, e026361.Research output: Contribution to journal › Article › peer-review
Hemodynamic Determinants of Elevated Blood Pressure and Hypertension in the Middle to Older-Age UK Population: A UK Biobank Imaging Study
Li, Y., Chan, E., Puyol-Antón, E., Ruijsink, B., Cecelja, M., King, A. P., Razavi, R. & Chowienczyk, P., Nov 2023, In: Hypertension. 80, 11, p. 2473-2484 12 p.Research output: Contribution to journal › Article › peer-review
Decline in Left Ventricular Early Systolic Function with Worsening Kidney Function in Children with Chronic Kidney Disease: Insights from the 4C and HOT-KID Studies
Gu, H., Azukaitis, K., Doyon, A., Erdem, S., Ranchin, B., Harambat, J., Lugani, F., Boguslavskyi, A., Cansick, J., Finlay, E., Gilbert, R., Kerecuk, L., Lunn, A., Maxwell, H., Morgan, H., Shenoy, M., Shroff, R., Subramaniam, P., Tizard, J. & Tse, Y. & 4 others, Simpson, J., Chowienczyk, P., Schaefer, F. & Sinha, M. D., 23 Nov 2023, In: Journal of The American Society of Echocardiography.Research output: Contribution to journal › Article › peer-review
Arterial Stiffness Can Be Modulated by Pressure-Independent Mechanisms in Hypertension
Faconti, L., Farukh, B., McNally, R., Webb, A. & Chowienczyk, P., 6 Aug 2019, In: Journal of the American Heart Association. 8, 15, p. e012601Research output: Contribution to journal › Article › peer-review
Post-exertional increase in first-phase ejection fraction in recreational marathon runners
Faconti, L., Parsons, I., Farukh, B., McNally, R., Nesti, L., Fang, L., Stacey, M., Hill, N., Woods, D. & Chowienczyk, P., 2020, In: JRSM cardiovascular disease. 9, p. 2048004020926366Research output: Contribution to journal › Article › peer-review
Differences in hypertension phenotypes between Africans and Europeans: role of environment
Faconti, L., McNally, R. J., Farukh, B., Adeyemi, O., Cruickshank, J. K., Wilkinson, I. B., Chowienczyk, P. J. & Ojji, D., Jul 2020, In: Journal of hypertension. 38, 7, p. 1278-1285 8 p.Research output: Contribution to journal › Article › peer-review
A review of the prescribing trend of thiazide-type and thiazide-like diuretics in hypertension: A UK perspective
McNally, R. J., Morselli, F., Farukh, B., Chowienczyk, P. J. & Faconti, L., Dec 2019, In: British Journal of Clinical Pharmacology. 85, 12, p. 2707-2713 7 p.Research output: Contribution to journal › Review article › peer-review
Impaired β 2 -adrenergic endothelium-dependent vasodilation in patients previously hospitalized with coronavirus disease 2019
Faconti, L., Farukh, B., McNally, R. J., Brett, S. & Chowienczyk, P. J., 1 Jun 2023, In: Journal of hypertension. 41, 6, p. 951-957 7 p.Research output: Contribution to journal › Article › peer-review
"Resistant hypertension, catecholamine excess, left ventricular hypertrophy and systolic dysfunction: hypertensive cardiomyopathy?"
Gould, A., Ambrosini, I., Masci, P.-G., Mcnally, R. J., Chowienczyk, P. J. & Faconti, L., Dec 2023, In: Journal of Human Hypertension. 37, 12, p. 1129-1130 2 p.Research output: Contribution to journal › Article › peer-review
Cardiac contractility is a key factor in determining pulse pressure and its peripheral amplification
Piccioli, F., Li, Y., Valiani, A., Caleffi, V., Chowienczyk, P. & Alastruey, J., 2023, In: Frontiers in Cardiovascular Medicine. 10, 1197842.Research output: Contribution to journal › Article › peer-review
Genetic-guided pharmacotherapy for venous thromboembolism: a systematic and critical review of economic evaluations
Lim, K. K., Koleva-Kolarova, R., Chowienczyk, P., Wolfe, C. D. A. & Fox-Rushby, J., Dec 2021, In: Pharmacogenomics Journal. 21, 6, p. 625-637Research output: Contribution to journal › Review article › peer-review
Genetic-Guided Pharmacotherapy for Atrial Fibrillation: A Systematic and Critical Review of Economic Evaluations
Kamil, A. A., Lim, K. K., Koleva-Kolarova, R., Chowienczyk, P., Wolfe, C. D. A. & Fox-Rushby, J., Mar 2022, In: Value in Health. 25, 3, p. 461-472Research output: Contribution to journal › Review article › peer-review
Effects of sleep disturbance on dyspnoea and impaired lung function following hospital admission due to COVID-19 in the UK: a prospective multicentre cohort study
PHOSP-COVID Study Collaborative Group, Chalder, T., Jolley, C. J., Shah, A. M., Man, W. D. C., Jackson, C., Stewart, I. D., Cunningham, P. S., Chalder, T., Harris, V. C., Ho, L. P., Howard, L. S., Jolley, C. J., Jones, M. G., Marks, M., Patel, B., Richardson, M., Rowlands, A. V., Saunders, R. M. & Scott, J. T. & 273 others, Shah, A. M., Singh, S. J., Man, W. D. C., Porter, J. C., Thompson, R., Evans, R., Jones, S. E., Rutter, M. K., Abel, K., Ahmad, S., Ahmed, R., Ali, M., Allen, R. J., Anderson, D., Armstrong, L., Armstrong, N., Ashworth, M., Ayoub, A., Baggott, R., Bailey, L., Baldwin, D., Ballard, C., Banerjee, A., Bates, A., Begum, M., Bell, D., Bell, R., Berry, C., Bhui, K., Bramham, K., Breen, G., Brookes, C., Broome, M., Brown, A., Brown, J., Brown, J., Brown, M., Burns, A., Butt, A., Byrne, S., Carson, G., Carter, P., Chambers, R. C., Chan, F., Chen, J., Cheng, Y., Chiribiri, A., Choudhury, N., Chowienczyk, P., Clark, D., Clark, C., Clarke, J., Cole, J., Connolly, B., Connor, L., Cook, A., Cooper, B., Cooper, J., Cooper, S., Craig, T., David, A., Davies, E., Davies, G., Davies, G., Davies, K., Davies, M. J., Dawson, J., Donaldson, A., Dong, T., Dougherty, A., Dowling, R., Dunn, S., Edwards, S., Elliott, A., Elliott, K., Evans, D., Evans, H., Evans, J., Evans, R., Evans, R., Evans, T., Finch, J., Fisher, H., Flynn, M., Ford, A., Francis, R., Gill, M., Goodwin, C., Gooptu, B., Gregory, H., Gregory, R., Grieve, D., Griffiths, L., Gupta, A., Hall, L., Harris, E., Harrison, P., Hart, N., Harvey, A., Harvey, M., Hayday, A., Henderson, M., Holden, S., Holland, M., Holmes, M., Hosseini, A., Hotopf, M., Hughes, A. D., Hughes, J., Hughes, R., Husain, M., Ismail, K., Jackson, T., Jacob, J., James, W. Y., Jenkins, R. G., Johnson, C., Johnson, S., Jones, D., Jones, G., Jones, H., Jones, I., Jones, L., Jones, S., Jose, S., Kaltsakas, G., Kelly, S., Kerr, S., Khan, F., King, B., Knight, S., Kon, S., Kon, S., Laing, C., Lasserson, D., Lawson, C., Lee, D., Lee, J. H., Lewis, D., Lewis, J., Li, X., Lim, L., Lloyd, A., Lord, J. M., Major, E., Malim, M., Mandal, S., Mangion, K., Marsh, S., Marshall, B., Marshall, M., Martin, J., Martinez, L. M., McMahon, M. J., Mehta, P., Miller, C., Mills, C., Mitchell, J., Mohamed, A., Mohammed, S., Morley, A., Morrow, A., Moss, A. J., Moss, P., Neal, A., Newby, D. E., Newman, J., Nicholson, T., O'Brien, C., Ostermann, M., Owen, J., Pariante, C., Parker, S., Patel, M., Patel, S., Payne, S., Pearce, L., Peng, Y., Pennington, C., Pfeffer, P., Plant, H., Plein, S., Porter, J., Powell, N., Pratt, J., Price, A., Price, C., Price, D., Prickett, A., Quigley, J., Qureshi, I. N., Rahman, N. M., Rees, M., Reynolds, W., Richards, A., Richardson, E., Roberts, K., Robertson, E., Robinson, E., Robinson, L., Rodger, J., Ross, A., Rowe, A., Rowland, A., Rowland, J., Russell, R., Sage, E. K., Saunders, K., Saunders, P., Shah, K., Shah, P., Shankar-Hari, M., Sharma, M., Sharpe, C., Shaw, A., Shaw, K., Simpson, J., Singh, C., Smith, A., Smith, D., Smith, S., Smith, J., Smith, L., Spencer, L. G., Stephenson, L., Stone, R., Tan, A. L., Taylor, A., Taylor, C., Taylor, J., Terry, S., Thomas, C., Thomas, D. C., Thomas, S., Thomas, A. K., Thompson, T., Thompson, A. A. R., Tilley, J., Tomlinson, J., Turner, S., Turner, K., Wade, P., Wainwright, T., Walker, S., Walsh, J. A., Walsh, S., Ward, T. J. C., Watson, E., Watson, L., Watson, J., Wessely, S., West, S., White, S., Whitney, J., Whittaker, S., Wild, J. M., Williams, B., Williams, N., Williams, J., Willoughby, J., Wilson, A., Wilson, D., Wood, C., Woods, J., Wright, C., Wright, L., Wright, S., Xu, M., Yip, K. P., Young, B., Young, S., Young, A. & Zhao, B., Aug 2023, In: The Lancet Respiratory Medicine. 11, 8, p. 673-684 12 p.Research output: Contribution to journal › Article › peer-review
Correction to: Histamine, mast cell tryptase and post-exercise hypotension in healthy and collapsed marathon runners
Parsons, I. T., Stacey, M. J., Faconti, L., Hill, N., O'Hara, J., Walter, E., Farukh, B., McNally, R., Sharp, H., Patten, A., Grimaldi, R., Gall, N., Chowienczyk, P. & Woods, D. R., Nov 2021, In: European Journal of Applied Physiology. 121, 11, p. 3257-3258 2 p.Research output: Contribution to journal › Article › peer-review
Intensive compared with less intensive blood pressure control to prevent adverse cardiac remodelling in children with chronic kidney disease (HOT-KID): a parallel-group, open-label, multicentre, randomised, controlled trial
Sinha, M. D., Gu, H., Douiri, A., Cansick, J., Finlay, E., Gilbert, R., Kerecuk, L., Lunn, A., Maxwell, H., Morgan, H., Shenoy, M., Shroff, R., Subramaniam, P., Tizard, J., Tse, Y., Rezavi, R., Simpson, J. M. & Chowienczyk, P. J., 4 Jan 2023, In: The Lancet Child & Adolescent Health. 7, 1, p. 26-36 11 p.Research output: Contribution to journal › Article › peer-review
RELATION OF PULSE WAVE VELOCITY TO CONTEMPORANEOUS AND HISTORICAL BLOOD PRESSURE IN FEMALE TWINS: Arterial Stiffness and Blood Pressure
Keehn, L., Mangino, M., Spector, T., Chowienczyk, P. & Cecelja, M., 1 Feb 2023, In: Hypertension. 80, 2, p. 361-369 9 p.Research output: Contribution to journal › Article › peer-review
Postprandial Responses to a Standardised Meal in Hypertension: The Mediatory Role of Visceral Fat Mass
Louca, B., Berry, S., Bermingham, K., Franks, P. W., Wolf, J., Spector, T., Valdes, A. M., Chowienczyk, P. & Menni, C., Nov 2022, In: Nutrients. 14, 21, p. 4499 4499.Research output: Contribution to journal › Article › peer-review
Lifestyle intervention in obese pregnancy and cardiac remodelling in 3-year olds: children of the UPBEAT RCT
UPBEAT Consortium, Dec 2022, In: International Journal of Obesity. 46, 12, p. 2145-2155 11 p.Research output: Contribution to journal › Article › peer-review
Reproducibility of sequential ambulatory blood pressure and pulse wave velocity measurements in normotensive and hypertensive individuals
Keehn, L., Hall, W., Berry, S., Sanders, T., Floyd, C. & Chowienczyk, P., 1 Dec 2022, In: Journal of hypertension. 40, 12, p. 2528-2537 10 p.Research output: Contribution to journal › Article › peer-review
AI-Enabled Assessment of Cardiac Systolic and Diastolic Function from Echocardiography
Puyol-Antón, E., Ruijsink, B., Sidhu, B. S., Gould, J., Porter, B., Elliott, M. K., Mehta, V., Gu, H., Rinaldi, C. A., cowie, M., Chowienczyk, P., Razavi, R. & King, A. P., 15 Sept 2022, Simplifying Medical Ultrasound - 3rd International Workshop, ASMUS 2022, held in Conjunction with MICCAI 2022, Proceedings. Aylward, S., Noble, J. A., Hu, Y., Lee, S.-L., Baum, Z. & Min, Z. (eds.). Springer Science and Business Media Deutschland GmbH, p. 75-85 11 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 13565 LNCS).Research output: Chapter in Book/Report/Conference proceeding › Conference paper › peer-review
A meta-analysis of the haemodynamics of primary hypertension in children and adults
Li, Y., Haseler, E., McNally, R., Sinha, M. & Chowienczyk, P., 1 Feb 2023, In: Journal of Hypertension. 41, 2, p. 212-219 8 p.Research output: Contribution to journal › Review article › peer-review
The hypertension optimal treatment in children with chronic kidney disease (HOT-KID study): a randomised trial to compare intensive versus standard blood pressure targets on target organ damage in childhood CKD
Sinha, M., Gu, H., Douiri, A., Rezavi, R., Simpson, J. & Chowienczyk, P., Sept 2022, In: Journal of Human Hypertension. 36, SUPPL 1, p. 8-8Research output: Contribution to journal › Meeting Abstract › peer-review
IMPAIRED BETA-2ADRENERGIC ENDOTHELIUM-DEPENDENT VASODILATION IS REVERSED BY PHOSPHODIESTERASE INHIBITION IN PATIENTS PREVIOUSLY HOSPITALIZED WITH COVID-19
Faconti, L., Farukh, B., McNally, R., Brett, S. & Chowienczyk, P., 1 Jun 2022, In: Journal of hypertension. 40, p. e172Research output: Contribution to journal › Poster abstract › peer-review
Sensitivity and reproducibility of inferior vena cava diameter and superior vena cava flow velocity measurements to changes in cardiac preload in subjects with hypertension
Mcnally, R. J., Farukh, B., Chowienczyk, P. J. & Faconti, L., 1 Jan 2022, In: Journal of Cardiovascular Echography. 32, 1, p. 6-11 6 p.Research output: Contribution to journal › Article › peer-review
The effect of water temperature on orthostatic tolerance: a randomised crossover trial
Parsons, I. T., Hockin, B. C. D., Taha, O. M., Heeney, N. D., Williams, E. L., Lucci, V. E. M., Lee, R. H. Y., Stacey, M. J., Gall, N., Chowienczyk, P., Woods, D. R. & Claydon, V. E., Apr 2022, In: Clinical Autonomic Research. 32, 2, p. 131-141 11 p.Research output: Contribution to journal › Article › peer-review
A pilot study to evaluate the erythrocyte glycocalyx sensitivity to sodium as a marker for cellular salt sensitivity in hypertension
McNally, R. J., Morselli, F., Farukh, B., Chowienczyk, P. J. & Faconti, L., 12 Apr 2022, In: Journal of Human Hypertension.Research output: Contribution to journal › Article › peer-review
Neuronal nitric oxide synthase regulates regional brain perfusion in healthy humans
O'gallagher, K., Puledda, F., O'daly, O., Ryan, M., Dancy, L., Chowienczyk, P. J., Zelaya, F., Goadsby, P. J. & Shah, A. M., 1 Apr 2022, In: Cardiovascular Research. 118, 5, p. 1321-1329 9 p.Research output: Contribution to journal › Article › peer-review
Fairness in Cardiac Magnetic Resonance Imaging: Assessing Sex and Racial Bias in Deep Learning-based Segmentation
Puyol-Anton, E., Ruijsink, B., Mariscal Harana, J., Piechnik, S. K., Neubauer, S., Petersen, S. E., Razavi, R., Chowienczyk, P. & King, A. P., 7 Apr 2022, In: Frontiers in Cardiovascular Medicine. 9, 859310.Research output: Contribution to journal › Article › peer-review
Wearable Photoplethysmography for Cardiovascular Monitoring
Charlton, P., Kyriacou, P., Mant, J., Marozas, V., Chowienczyk, P. & Alastruey, J., 11 Mar 2022, In: Proceedings of the IEEE. 110, 3, p. 355-381 27 p.Research output: Contribution to journal › Article › peer-review
Effect of diuretics on plasma aldosterone and potassium in primary hypertension: A systematic review and meta-analysis
McNally, R. J., Farukh, B., Chowienczyk, P. J. & Faconti, L., 11 Apr 2022, In: British Journal of Clinical Pharmacology. 88, 5, p. 1964-1977 14 p.Research output: Contribution to journal › Review article › peer-review
Genetic-Guided Pharmacotherapy for Atrial Fibrillation: A Systematic and Critical Review of Economic Evaluations
Kamil, A. A., Lim, K. K., Koleva-Kolarova, R., Chowienczyk, P., Wolfe, C. D. A. & Fox-Rushby, J., 2 Dec 2021, (E-pub ahead of print) In: Value in Health. 25, 3Research output: Contribution to journal › Article › peer-review
Cardiovascular health and risk of hospitalization with COVID-19: a Mendelian Randomization study
Cecelja, M., Lewis, C. M., Shah, A. M. & Chowienczyk, P., 19 Nov 2021, (E-pub ahead of print) In: JRSM cardiovascular disease. 10Research output: Contribution to journal › Article › peer-review
Novel Pressure Wave Separation Analysis for Cardiovascular Function Assessment Highlights Major Role of Aortic Root
Vennin, S., Li, Y., Mariscal Harana, J., Charlton, P., Fok, H., Gu, H., Chowienczyk, P. & Alastruey, J., 12 Nov 2021, (E-pub ahead of print) In: IEEE Transactions on Biomedical Engineering. PPResearch output: Contribution to journal › Article › peer-review
First phase ejection fraction in aortic stenosis: A useful new measure of early left ventricular systolic dysfunction
Saeed, S., Gu, H., Rajani, R., Chowienczyk, P. & Chambers, J. B., 1 Nov 2021, In: Journal of Clinical Ultrasound. 49, 9, p. 932-935 4 p.Research output: Contribution to journal › Article › peer-review
Genetic-guided pharmacotherapy for venous thromboembolism: a systematic and critical review of economic evaluations
Lim, K. K., Koleva-Kolarova, R., Chowienczyk, P., Wolfe, C. D. A. & Fox-Rushby, J., Dec 2021, In: Pharmacogenomics Journal. 21, 6, p. 625-637 13 p.Research output: Contribution to journal › Review article › peer-review
First-phase ejection fraction by cardiovascular magnetic resonance predicts outcomes in aortic stenosis
Gu, H., Bing, R., Chin, C., Fang, L., White, A. C., Everett, R., Spath, N., Park, E., Chambers, J. B., Newby, D. E., Chiribiri, A., Dweck, M. R. & Chowienczyk, P., 10 Jun 2021, In: Journal of Cardiovascular Magnetic Resonance. 23, 1, p. 73 73.Research output: Contribution to journal › Article › peer-review
Direct cardiac versus systemic effects of inorganic nitrite on human left ventricular function: Effect of inorganic nitrite on LV function
O'Gallagher, K., Shah, A., Ryan, M., Roomi, A., Gu, H., Chowienczyk, P., Webb, A. & Kevin, O., 2021, (Accepted/In press) In: American Journal of Physiology.Research output: Contribution to journal › Article › peer-review
Impact of arterio-ventricular interaction on first-phase ejection fraction in aortic stenosis
Einarsen, E., Hjertaas, J. J., Gu, H., Matre, K., Chowienczyk, P. J., Gerdts, E., Chambers, J. B. & Saeed, S., 1 Jun 2021, In: European heart journal. Cardiovascular Imaging. 22, 6, p. 650-657 8 p.Research output: Contribution to journal › Article › peer-review
Estimating pulse wave velocity from the radial pressure wave using machine learning algorithms
Jin, W., Chowienczyk, P. & Alastruey, J., Jun 2021, In: PLoS ONE. 16, 6 June, p. e0245026 e0245026.Research output: Contribution to journal › Article › peer-review
The physiological effects of cardiac resynchronization therapy on aortic and pulmonary flow and dynamic and static components of systemic impedance
Sidhu, B., Claridge, S., Gu, H., Li, Y., Gould, J., Porter, B., Elliott, M., Mehta, V., Jackson, T., Patterson, T., Briceno, N., Lee, J., Redwood, S., Adhya, S., Niederer, S., Chowienczyk, P. & Rinaldi, C. A., 25 May 2021, (Accepted/In press) In: Heart rhythm : the official journal of the Heart Rhythm Society.Research output: Contribution to journal › Article › peer-review
Central aortic blood pressure from ultrasound wall-tracking of the carotid artery in children: Comparison with invasive measurements and radial tonometry
Milne, L., Keehn, L., Guilcher, A., Reidy, J. F., Karunanithy, N., Rosenthal, E., Qureshi, S., Chowienczyk, P. J. & Sinha, M. D., 21 May 2015, In: Hypertension. 65, 5, p. 1141-1146 6 p.Research output: Contribution to journal › Article › peer-review
Dietary nitrate prevents progression of carotid subclinical atherosclerosis through blood pressure-independent mechanisms in patients with or at risk of type 2 diabetes mellitus
Morselli, F., Faconti, L., Mills, C. E., Morant, S., Chowienczyk, P. J., Yeung, J. A., Cavarape, A., Cruickshank, J. K. & Webb, A. J., Dec 2021, In: British Journal of Clinical Pharmacology. 87, 12, p. 4726-4736 11 p.Research output: Contribution to journal › Article › peer-review
Research

Centre for Ageing Resilience In a Changing Environment - CARICE
Welcome to the Centre for Ageing Resilience in a Changing Environment: CARICE
News
Lower blood pressure reduces cardiovascular disease for children with chronic kidney disease
The HOT-KID clinical trial looked at how lowering blood pressure in children with chronic kidney disease could prevent cardiac remodelling and associated...

Paper by King's researchers makes Readers' Choice List 2021
The article was selected as one of The Pharmacogenomics Journal’s 15 most cited or shared articles in 2021.

Researchers reveal that first-phase ejection fraction is associated with increased mortality in patients with COVID-19
Researchers reveal that first-phase ejection fraction is associated with increased mortality in patients with COVID-19
