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Polychronis  Pavlidis

Polychronis Pavlidis PhD, FRCP, FHEA

Adj Senior Lecturer & Consultant Gastroenterologist

Research interests

  • Immunology
  • Informatics

Biography

Polychronis is a Consultant Gastroenterologist based at King’s College Hospital and holds an adjunct appointment as Senior Lecturer with the Department of Inflammation Biology at King’s College London. His clinical and research interests focus on inflammatory bowel disease (such as Crohn’s disease and ulcerative colitis) but also on gut inflammation in the context of transplantation, immunotherapies and chronic liver immune mediated conditions like primary sclerosing cholangitis.

Following his medical degree (University of Thessaly, Larissa, Greece, 2006) he undertook post-graduate training in London and the south-east of England, working at international centres of excellence including King’s College Hospital and Guy’s and St Thomas’ NHS Foundation Trust. He holds a PhD in Transplantation Immunology and Mucosal Biology from King’s College London (2018) for studying the role of interleukin 22 in inflammatory bowel disease and acute gastrointestinal graft versus host disease. He was the NIHR Academic Clinical Lecturer in Gastroenterology at King’s Health Partners from 2018 to 2021.

His translational research work aims to deliver stratified medicine approaches in chronic gut inflammation as well as inform evidence-based practice and has been funded by national funding streams (NIHR), charities (CCUK, Guts UK) and other stakeholders. Presentations at national and international fora have received multiple awards while manuscripts have been accepted for publication by high impact journals like Nature Communications, Cell Reports and Gut.Polychronis has co-authored leading national and international guidelines as well as consensus statements on IBD management (BSG 2024), personalised medicine approaches (ECCO 2021) and checkpoint inhibitor induced colitis (BSG 2020). He is an elected member of the BSG IBD Clinical Research Group and contributes to the BSGAR IUS subcommittee’s proceedings.

ORCID Publications

    News

    Studies reveal complexity of immune responses in patients receiving treatment for Crohn's disease and ulcerative colitis

    The findings provide a better understanding of the interactions between the immune system and epithelium, with potential to inform novel treatments.

    IBD

      News

      Studies reveal complexity of immune responses in patients receiving treatment for Crohn's disease and ulcerative colitis

      The findings provide a better understanding of the interactions between the immune system and epithelium, with potential to inform novel treatments.

      IBD