Professor Qingbo Xu Visiting BHF John Parker Chair of Cardiovascular Sciences Contact details qingbo.xu@kcl.ac.uk
B cell-derived anti-beta 2 glycoprotein I antibody contributes to hyperhomocysteinaemia-aggravated abdominal aortic aneurysm Hyaluronan promotes the regeneration of vascular smooth muscle with potent contractile function in rapidly biodegradable vascular grafts Impact of Local Alloimmunity and Recipient Cells in Transplant Arteriosclerosis NSun2 regulates aneurysm formation by promoting autotaxin expression and T cell recruitment Shikonin attenuates hyperhomocysteinemia-induced CD4+ T cell inflammatory activation and atherosclerosis in ApoE−/− mice by metabolic suppression Single-cell gene profiling and lineage tracing analyses revealed novel mechanisms of endothelial repair by progenitors Adventitial Cell Atlas of wt (Wild Type) and ApoE (Apolipoprotein E)-Deficient Mice Defined by Single-Cell RNA Sequencing DKK3 (Dikkopf-3) Transdifferentiates Fibroblasts Into Functional Endothelial Cells-Brief Report Encapsulation of macrophages enhances their retention and angiogenic potential Ion Channels and Vascular Diseases Patient-Specific iPSC Model of a Genetic Vascular Dementia Syndrome Reveals Failure of Mural Cells to Stabilize Capillary Structures Protective Role of RNA Helicase DEAD-Box Protein 5 in Smooth Muscle Cell Proliferation and Vascular Remodeling Recipient c-Kit Lineage Cells Repopulate Smooth Muscle Cells of Transplant Arteriosclerosis in Mouse Models: Stem Cells Repopulate Allograft Vessels Single-cell RNA-sequencing and Metabolomics Analyses Reveal the Contribution of Perivascular Adipose Tissue Stem Cells to Vascular Remodeling: Perivascular stem cells and vascular remodeling Adventitial Sca1+ Cells Transduced with ETV2 Are Committed to the Endothelial Fate and Improve Vascular Remodeling after Injury Binding of Dickkopf-3 to CXCR7 Enhances Vascular Progenitor Cell Migration and Degradable Graft Regeneration Cartilage oligomeric matrix protein is a novel notch ligand driving embryonic stem cell differentiation towards the smooth muscle lineage COMP-prohibitin 2 interaction maintains mitochondrial homeostasis and controls smooth muscle cell identity DKK3 (Dickkopf 3) Alters Atherosclerotic Plaque Phenotype Involving Vascular Progenitor and Fibroblast Differentiation into Smooth Muscle Cells Genetic lineage tracing analysis of c-kit+ stem/progenitor cells revealed a contribution to vascular injury-induced neointimal lesions GSNOR modulates hyperhomocysteinemia-induced T cell activation and atherosclerosis by switching Akt S-nitrosylation to phosphorylation Histone Deacetylase 7-Derived Peptides Play a Vital Role in Vascular Repair and Regeneration Impact of miRNA in Atherosclerosis PKM2-dependent metabolic reprogramming in CD4+ T cells is crucial for hyperhomocysteinemia-accelerated atherosclerosis Response of vascular mesenchymal stem/progenitor cells to hyperlipidemia Smooth muscle cells differentiated from mesenchymal stem cells are regulated by microRNAs and suitable for vascular tissue grafts A Cytokine-Like Protein Dickkopf-Related Protein 3 Is Atheroprotective Adventitial SCA-1+ Progenitor Cell Gene Sequencing Reveals the Mechanisms of Cell Migration in Response to Hyperlipidemia Differentiation and application of induced pluripotent stem cell?derived vascular smooth muscle cells Homocysteine activates B cells via regulating PKM2-dependent metabolic reprogramming Hypoxia inducible factor as a therapeutic target for atherosclerosis Leptin Induces Sca-1+ Progenitor Cell Migration Enhancing Neointimal Lesions in Vessel-Injury Mouse Models Mesenchymal stem cells and vascular regeneration Quaking Is a Key Regulator of Endothelial Cell Differentiation, Neovascularization, and Angiogenesis Reactive oxygen species generation and atherosclerosis Transdifferentiated Human Vascular Smooth Muscle Cells are a New Potential Cell Source for Endothelial Regeneration Unspliced XBP1 Confers VSMC Homeostasis and Prevents Aortic Aneurysm Formation via FoxO4 Interaction Hyaluronan is Crucial for Stem Cell Differentiation into Smooth Muscle Lineage Microsomal Prostaglandin e Synthase-1-Derived PGE2 Inhibits Vascular Smooth Muscle Cell Calcification NSun2 deficiency protects endothelium from inflammation via mRNA methylation of ICAM-1 Reprogramming towards Endothelial Cells for Vascular Regeneration Vascular regeneration by stem/progenitor cells Vascular Stem/Progenitor Cell Migration Induced by Smooth Muscle Cell-Derived Chemokine (C-C Motif) Ligand 2 and Chemokine (C-X-C motif) Ligand 1 Contributes to Neointima Formation XBP1 splicing triggers miR-150 transfer from smooth muscle cells to endothelial cells via extracellular vesicles ADAMTS-7 Inhibits Re-endothelialization of Injured Arteries and Promotes Vascular Remodeling Through Cleavage of Thrombospondin-1 C-Kit+ progenitors generate vascular cells for tissue-engineered grafts through modulation of the Wnt/Klf4 pathway Dickkopf homolog 3 induces stem cell differentiation into smooth muscle lineage via ATF6 signalling Enzyme-functionalized vascular grafts catalyze in-situ release of nitric oxide from exogenous NO prodrug Expression of Human Tissue Factor Pathway Inhibitor on Vascular Smooth Muscle Cells Inhibits Secretion of Macrophage Migration Inhibitory Factor and Attenuates Atherosclerosis in ApoE-/- Mice Generation and grafting of tissue-engineered vessels in a mouse model View all publications