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Rachel Woodham

Rachel Woodham

Senior Trial Manager

Contact details

Biography

Rachel has been working at King's College London as a Senior Trial Manager for the HOME Trial since May 2025. Rachel is working on an NIHR funded multi-site effectiveness clinical trial comparing standard care to standard care and transcranial direct current stimulation (tDCS) for the treatment of current major depressive episode.

Previously she worked at the University of East London where we completed the initial pilot trial of home based tDCS and our efficacy trial comparing active and sham tDCS for the treatment of depression.

Rachel has a BSc in Psychology from the University of Sussex and an MSc in Cognitive and Clinical Neuroscience. Prior to working as a research assistant, she worked in a community service supporting people with substance use issues.

Research Interests

  • Neuromodulation
  • tDCS
  • Depression
  • Bipolar depression

Key Publications

Woodham, R.D., Selvaraj, S., Lajmi, N. et al. 2024. Home-based transcranial direct current stimulation treatment for major depressive disorder: a fully remote phase 2 randomized sham-controlled trial. Nature Medicine. 31: 87-95. https://doi.org/10.1038/s41591-024-03305-y

Woodham, R.D., Selvaraj, S., Lajmi, N. et al. 2025. Home-based transcranial direct current stimulation for major depressive disorder: 6-month follow-up from randomised sham-controlled trial and open-label treatment phases. Journal of Psychiatric Research. https://doi.org/10.1016/j.jpsychires.2025.03.047

Woodham, R.D., Rimmer, R.M., Young, A.H. & Fu, C.H.Y. 2022. Adjunctive home-based transcranial direct current stimulation treatment for major depression with real-time remote supervision: An open-label, single-arm feasibility study with long term outcomes. Journal of Psychiatric Research. 153: 197-205. https://doi.org/10.1016/j.jpsychires.2022.07.026

Woodham, R.D., Rimmer, R.M., Mutz, J. & Fu, C.H.Y. 2021. Is tDCS a potential first line treatment for major depression? International Review of Psychiatry. 33: 250-265. https://doi.org/10.1080/09540261.2021.1879030

Ghazi-Noori, A-R., Woodham, R.D., Rezaei, H., Sharif, M.S., Bramon, E., Ritter, P., Bauer, M., Young, A,H., Fu, C.H.Y. 2024. Home-based transcranial direct current stimulation in bipolar depression: an open-label treatment study of clinical outcomes, acceptability and adverse events. International Journal of Bipolar Disorders. 12:30. https://doi.org/10.1186/s40345-024-00352-9

Rimmer, R.M., Woodham, R.D., Cahill, S. & Fu, C.H.Y. 2024. Acceptability of home-based transcranial direct current stimulation (tDCS) in major depression: a qualitative analysis of individual experiences. Mental Health Review Journal. 21: 79-91. https://doi.org/10.1108/MHRJ-07-2022-0050

Rezaei, H., Woodham, R.D., Ghazi-Noori, AR. et al. 2025. Effect of home-based transcranial direct current stimulation (tDCS) on cognitive functioning in bipolar depression: an open-label, single-arm acceptability and feasibility study. International Journal of Bipolar Disorders. 13: 11. https://doi.org/10.1186/s40345-025-00376-9

Xiao, W., Moncy, J.C., Ghazi-Noori A-R., Woodham, R.D., Rezaei. H., Bramon, E., Ritter, P., Bauer, M., Young, A.H. & Fu, C.H.Y. 2024. Enhanced network synchronization connectivity following transcranial direct current stimulation (tDCS) in bipolar depression: Effects on EEG oscillations and deep learning-based predictors of clinical remission. Journal of Affective Disorders. 15;369:576-587. http://doi.org/10.1016/j.jad.2024.09.054

Fu, C.H.Y., Erus, G., Fan, Y. et al. 2023. AI-based dimensional neuroimaging system for characterizing heterogeneity in brain structure and function in major depressive disorder: COORDINATE-MDD consortium design and rationale. BMC Psychiatry 23: 59. https://doi.org/10.1186/s12888-022-04509-7

Xiao, W., Moncy, J.C., Ghazi-Noori A-R., Woodham, R.D. et al. 2025. Home-based transcranial direct current stimulation (tDCS) in major depressive disorder: Enhanced network synchronization with active relative to sham and deep learning-based predictors of remission. Personalized Medicine in Psychiatry. 49–50. https://doi.org/10.1016/j.pmip.2024.100147

Rezaei, H., Woodham, R.D., Ghazi-Noori, AR. et al. 2026. Home-based transcranial direct current stimulation (tDCS) for bipolar depression: effects on quality of life and functioning—an open-label study. Qual Life Res 35, 33. https://doi.org/10.1007/s11136-025-04135-2

Hieronymus, F., Huneke, N.T.M., Månsson, D., Rehn, E.M., Hagsäter, M., Woodham, R.D. et al. 2026. Assessing the presence of biasing and non-biasing unblinding in a randomized controlled trial of a home-use tDCS device: An exploratory analysis. Journal of Affective Disorders. https://doi.org/10.1016/j.jad.2026.121553