Professor Steven Sacks Academics Director of the Protein Therapeutics Laboratory Former Director of MRC Centre for Transplantation . Contact details steven.sacks@kcl.ac.uk +44 (0) 20 07188 5669
Complement in ischaemia–reperfusion injury and transplantation Howard, M. C., Nauser, C. L., Farrar, C. A. & Sacks, S. H., Dec 2021, In: Seminars In Immunopathology. 43, 6, p. 789-797 9 p. Research output: Contribution to journal › Review article › peer-review. DOIs: https://doi.org/10.1007/s00281-021-00896-3 PD-L1 signaling on human memory CD4+ T cells induces a regulatory phenotype Fanelli, G., Romano, M., Nova Lamperti, E., Werner Sunderland, M., Nerviani, A., Scotta, C., Bombardieri, M., Quezada, S. A., Sacks, S., Noelle, R. J., Pitzalis, C., Lechler, R., Lombardi, G. & Becker, P., 19 Apr 2021, (Accepted/In press) In: PLoS biology. Research output: Contribution to journal › Article › peer-review Complement activation is a crucial driver of acute kidney injury in rhabdomyolysis Boudhabhay, I., Poillerat, V., Grunenwald, A., Torset, C., Leon, J., Daugan, M. V., Lucibello, F., El Karoui, K., Ydee, A., Chauvet, S., Girardie, P., Sacks, S., Farrar, C. A., Garred, P., Berthaud, R., Le Quintrec, M., Rabant, M., de Lonlay, P., Rambaud, C., Gnemmi, V., & 3 othersFremeaux-Bacchi, V., Frimat, M. & Roumenina, L. T., Mar 2021, In: Kidney International. 99, 3, p. 581-597 17 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.kint.2020.09.033 Does the Lectin Complement Pathway Link Kawasaki Disease and SARS-CoV-2? Polycarpou, A., Grigoriadou, S., Klavinskis, L. & Sacks, S., 14 Jan 2021, In: Frontiers in Immunology. 11, 604512. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.3389/fimmu.2020.604512 Ex vivo delivery of Mirococept: A dose finding study in pig kidney after showing a low dose is insufficient to reduce delayed graft function in human kidney Kassimatis, T., Greenlaw, R., Hunter, J. P., Douiri, A., Flach, C., Rebollo-Mesa, I., Nichols, L. L., Qasem, A., Danzi, G., Olsburgh, J., Drage, M., Friend, P. J., Neri, F., Karegli, J., Horsfield, C., Smith, R. A. & Sacks, S. H., 17 Aug 2020, In: American Journal of Transplantation. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1111/ajt.16265 Rationale for Targeting Complement in COVID-19 Polycarpou, A., Howard, M., Farrar, C., Greenlaw, R., Fanelli, G., Wallis, R., Klavinskis, L. & Sacks, S., 7 Aug 2020, In: EMBO Molecular Medicine. 12, 8, e12642. Research output: Contribution to journal › Review article › peer-review. DOIs: https://doi.org/10.15252/emmm.202012642, https://doi.org/10.15252/emmm.202012642 Successful simultaneous liver-kidney transplantation for renal failure associated with hereditary complement C3 deficiency Nayagam, J. S., McGrath, S., Montasser, M., Delaney, M., Cairns, T. D., Marchbank, K. J., Denton, H., Yang, Y., Sacks, S. H., Cook, H. T., Shah, S., Heaton, N., Pickering, M. C. & Suddle, A., 1 Aug 2020, In: American Journal of Transplantation. 20, 8, p. 2260-2263 4 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1111/ajt.15785 Fucose as a new therapeutic target in renal transplantation Howard, M., Nauser, C., Vizitiu, D. & Sacks, S., 30 May 2020, In: Pediatric Nephrology. Research output: Contribution to journal › Review article › peer-review. DOIs: https://doi.org/10.1007/s00467-020-04588-2 l-Fucose prevention of renal ischaemia/reperfusion injury in Mice Howard, M. C., Nauser, C. L., Farrar, C. A., Wallis, R. & Sacks, S. H., Jan 2020, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 34, 1, p. 822-834 13 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1096/fj.201901582R The impact of donor and recipient common clinical and genetic variation on estimated glomerular filtration rate in a European renal transplant population The UK Ireland Renal Transplant Consortium, DeKAF Genomics and GEN03 Studies & The International Genetics and Translational Research in Transplantation Network, 1 Aug 2019, In: American Journal of Transplantation. 19, 8, p. 2262-2273 12 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1111/ajt.15326 View all publications