Biography
I joined King’s College London in 2009 as a 1+3 MSc/PhD student, after completing my undergraduate degree in Human Sciences at University College London. In 2014, I graduated with a PhD from the Social, Genetic and Developmental Psychiatry (SGDP) department, where I was also awarded the Gottesman-Shields PhD Prize. In 2016, after a two-year postdoctoral training position as part of the Biomedical Research Centre, I was awarded a Medical Research Council Skills Development Fellowship.
My current work combines wet-lab experimental methods with cutting-edge population genetic methods to investigate which biological mechanisms are important in mediating risk for psychiatric disorders, such as major depression, and identifying methods to reverse these risk mechanisms (e.g. drug repositioning). Biological mechanisms of particular interest include: telomere shortening, inflammation, neurogenesis, and human endogenous retroviral expression.
I currently lead the Psychiatric Biogerontology & Translational Medicine Group, where I supervise MSc students, PhD students and postdoctoral researchers. I lecture on a number of MSc courses, and in particular, the Genes, Environment & Development in Psychology & Psychiatry MSc.
Research interests:
- Telomeres
- Genetics
- Biomarkers
- Neuroscience
- Cell development
Research groups:
Psychiatric Biogerontology & Translational Medicine (Powell)
Teaching:
Molecular genetics
Expertise and Public Engagement:
2017, Pint of Science: I gave a talk about stem cells and drug repositioning for depression, entitled “Highs & lows: understanding the effects of drugs”, London.
2017, BBC Radio 4: I discussed the prospect of using stem cells for drug repositioning in depression as part of the “All in the Mind” programme (goo.gl/nQpqMi).
2017, MRC Festival: I talked to school children about genetics and taught them how to extract DNA from strawberries.
2016, Genes and Tonic event: I led practical demonstrations on DNA extraction at The Accessible Genetic Consortium, which aims to make science more accessible to the public.
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Peña, E., Powell, T., Arenas, C., Cardoner, N., Rebasa, P., Luna, A., Caixà s, A. & Rosa, A., 13 Jun 2020, (Accepted/In press) In : Surgery for obesity and related diseases. Research output: Contribution to journal - Article
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Warre Cornish, K., Perfect, L., Rafagnin Duarte, R. R., Reid, M., Raval, P., McAlonan, G., Loth, E., Murphy, D., Powell, T., Vernon, A., Srivastava, D. & Price, J., 10 Jun 2020, (Accepted/In press) In : Science Advances. Research output: Contribution to journal - Article
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Powell, T. R., R. Duarte, R. R., Hotopf, M., Hatch, S. L., de Mulder, M., Breen, G. D., Lewis, C. M. & Nixon, D. F., 2020, In : Scientific Reports. 10, 1, 3304 . Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1038/s41598-020-59256-0
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Smeeth, D. M., Kourouzidou, I., Rafagnin Duarte, R. R., Powell, T. & Thuret, S., 12 Dec 2019, (Accepted/In press) In : Neuroscience. Research output: Contribution to journal - Article
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Smeeth, D. M., Dima, D., Jones, L., Jones, I., Craddock, N., Owen, M. J., Rietschel, M., Maier, W., Korszun, A., Rice, J. P., Mors, O., Preisig, M., Uher, R., Lewis, C. M., Thuret, S. & Powell, T. R., Aug 2019, In : Psychoneuroendocrinology. 106, p. 284-292 9 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1016/j.psyneuen.2019.04.011
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Strawbridge, R., Hodsoll, J., Powell, T. R., Hotopf, M., Hatch, S. L., Breen, G. & Cleare, A. J., 17 Dec 2018, In : Journal of Affective Disorders. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1016/j.jad.2018.12.037
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Duarte, R. R. R., Bachtel, N., Cotel, M-C., Lee, S. H., Selvackadunco, S., Watson, I. A., Hovsepian, G. A., Troakes, C., Breen, G. D., Nixon, D. F., Murray, R. M., Bray, N. J., Eleftherianos, I., Vernon, A. C., Powell, T. R. & Srivastava, D. P., 15 Jul 2019, In : Biological psychiatry. 86, 2, p. 120-130 11 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1101/468546https://doi.org/10.1016/j.biopsych.2019.03.977https://doi.org/10.1016/j.biopsych.2019.03.977https://doi.org/10.1016/j.biopsych.2019.03.977
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Coutts, F., Palmos, A., Duarte, R. R. R., de Jong, S., Lewis, C. M., Dima, D. & Powell, T. R., 18 Dec 2018, In : Neuropsychopharmacology. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1038/s41386-018-0289-0
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Powell, T. R., De Jong, S., Breen, G., Lewis, C. M. & Dima, D., 4 Dec 2018, In : Human Brain Mapping. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1002/hbm.24487
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Palmos, A., Watson, S., Hughes, T., Finkelmeyer, A., McAllister-Williams, H., Ferrier, N., Anderson, I. M., Nair, R., Young, A. H., Strawbridge, R., Cleare, A. J., Chung, R., Frissa, S., Goodwin, L., Hotopf, M., Hatch, S. L., Wang, H., Collier, D. A., Thuret, S., Breen, G. & 1 others, Powell, T. R., Jan 2019, In : British Journal of Psychiatry Open . 5, 1, e3. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1192/bjo.2018.80