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Timothy Powell

Dr Timothy Powell PhD

Senior Lecturer in Translational Genetics & Neuroscience

Research interests

  • Biomedical and life sciences

Biography

I joined King’s College London in 2009 as a 1+3 MSc/PhD student, after completing my undergraduate degree in Human Sciences at University College London. In 2014, I graduated with a PhD from the Social, Genetic & Developmental Psychiatry (SGDP) department, where I was also awarded the Gottesman-Shields PhD Prize. In 2016, after a two-year postdoctoral training position as part of the Biomedical Research Centre, I was awarded a Medical Research Council Skills Development Fellowship. 

My current work combines wet-lab experimental methods with cutting-edge population genetic methods to investigate which biological mechanisms are important in mediating risk for psychiatric disorders, such as major depression, and identifying methods to reverse these risk mechanisms (e.g. drug repositioning). Biological mechanisms of particular interest include:  telomere shortening, inflammation, neurogenesis, and human endogenous retroviral expression. 

I currently lead the Psychiatric Biogerontology & Translational Medicine Group, where I supervise MSc students, PhD students and postdoctoral researchers. I lecture on a number of MSc courses, and in particular, the Developmental Psychology & Psychopathology MSc. 

Research interests:

  •  Telomeres 
  •  Genetics 
  •  Biomarkers 
  •  Neuroscience 
  •  Cell development 

Research groups:

Psychiatric Biogerontology & Translational Medicine (Powell)

Teaching:

Molecular genetics 

Expertise and Public Engagement:

2017, Pint of Science: I gave a talk about stem cells and drug repositioning for depression, entitled “Highs & lows: understanding the effects of drugs”, London. 

2017, BBC Radio 4: I discussed the prospect of using stem cells for drug repositioning in depression as part of the “All in the Mind” programme (goo.gl/nQpqMi). 

2017, MRC Festival: I talked to school children about genetics and taught them how to extract DNA from strawberries. 

2016, Genes and Tonic event: I led practical demonstrations on DNA extraction at The Accessible Genetic Consortium, which aims to make science more accessible to the public. 

    News

    Ancient viral DNA in the human genome linked to major psychiatric disorders

    New research has found that thousands of DNA sequences originating from ancient viral infections are expressed in the brain, with some contributing to...

    brain and genetics

    Individuals at risk of severe COVID-19 might have lower levels of inflammation prior to infection

    New research from King's has identified three key inflammatory proteins which are lower in individuals at risk of severe COVID-19.

    Down syndrome & Alzheimer's gene

      News

      Ancient viral DNA in the human genome linked to major psychiatric disorders

      New research has found that thousands of DNA sequences originating from ancient viral infections are expressed in the brain, with some contributing to...

      brain and genetics

      Individuals at risk of severe COVID-19 might have lower levels of inflammation prior to infection

      New research from King's has identified three key inflammatory proteins which are lower in individuals at risk of severe COVID-19.

      Down syndrome & Alzheimer's gene