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Biography

We research neural connectivity in autism spectrum disorders and are working on an understanding of structural changes in neural connectivity in mice mutant for high confidence autism genes. We focus our analyses on the medial prefrontal and somatosensory cortex, regions believed to function as hubs to integrate neural circuits controlling social behaviour. We specifically study the development of circuits in these areas from early postnatal times to adult mice which enables us to detect transient defects in neural circuit development. To understand the defects on a molecular level, we investigate the hypothesis that critical circuits are disrupted due to a disturbance of microglia function and/or neuronal autophagy.

Please see my Research Staff Profile for more detail

Find out more about my research:

MRC - Uwe Drescher

CDN - Uwe Drescher

Key publications:

View all publications

Key collaborators:

  • Dr Michael Reber Krembil Research Institute, Toronto
  • Prof Robert Hindges, CDN, KCL
  • Prof Matthias Gautel, Randall Institute, KCL
  • Franko Weth, KIT, Karlsruhe Germany