Dr Yau Mun Lim obtained his BSc degree in Biomedical Sciences at Imperial College London in 2013. During this time, he developed an interest in Alzheimer’s disease and its underlying cause. He then continued at Imperial College London to complete his MRes in Experimental Neuroscience, graduating in 2014. In 2018, Yau completed his PhD in Old Age Psychiatry at King’s College London funded by the Alzheimer’s Society, developing a cellular-based disease model for TREM2, a risk gene for Alzheimer’s disease. This involved being self-taught the currently popular gene editing technology CRISPR-Cas9, which at the time was just emerging, to knock-in the disease-associated TREM2 variant into cells. Currently, he is applying his expertise in gene editing as an option for cancer therapy and working together with his colleagues within Professor Khuloud Al-Jamal’s group to use various nanoparticles to deliver therapeutic CRISPR-Cas9 into tumours. Yau is also an expert in immunohistochemistry, aiding his colleagues in staining formalin-fixed tumour tissues after in vivo experiments.
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