Mitotic cell division is essential for all eukaryotic life and has been the subject of significant work since the description of karyomitosis (threadlike metamorphosis of the nucleus) by Walther Flemming in 1882. Nevertheless, there are many unresolved questions, primarily due to the complexity of the mitotic apparatus and the plasticity of mitosis in different cellular contexts. The Auckland Lab aims to address this by using advanced cell biology and biochemical techniques to understand a myriad of mitotic mechanisms in different human cell types.