Paula Booth's group works at the interface of Chemistry and Biology to elucidate the mechanisms by which proteins fold, assemble and communicate within biological membranes. Emphasis is placed on understanding the role of membrane lipids in regulating protein folding and function. Membrane proteins account for about 30% of all cell proteins, and play pivotal roles in life reflected in their domination of drug targets. The group’s research aims to not only solve fundamental questions relating to membrane protein biogenesis and folding, but also to exploit the self-assembly of artificial biomembranes for Synthetic Biology and catalytic applications.