Cariology & Operative Dentistry

1995 - 1998   Medical Research Council Clinical Training Fellowship G84/4339).    
(Co-PI (Watson TF, Kidd EAM) –planned and co-wrote application for funding my doctoral research studies – resulted in award of PhD, 6 publications)  

1997 - 2009     Consultancy grants from Mediteam / Orasolv (Sweden) for independent, experimental, evaluation of Carisolv^TM.   
(Clinical and lab studies chief investigator – resulted in three publications)                                                                          

2001 - 2002     Charitable Foundation grant (R001145), Guy's, King's and St. Thomas' Dental Institute: Molecular quantitation, species diversity and 3-dimensional distribution of the microflora in human carious dentine.                                 
(PI (Wade W, Watson TF) –funded a post-doc – 2 publications.                             

2002 - 2006     Engineering & Physical Sciences Research Council (EPSRC) (GR/R66906/01).  Bioactive Air-abrasion in Restorative Dentistry:  development and high-speed confocal microscopic assessment.   
(Co-PI (Watson TF, Sherriff M) – co-wrote the application which funded a PG doctoral student which I supervised – 5 publications).

2006 - 2007     3MESPE Industrial grant - In-vitro investigation of the efficacy of an enzymatic caries removal system, Biosolv™.                                                                            
(Chief Investigator running a clinical trial (European, multi-centre, RCT) of SFC-V, an enzymatic dentine caries removal system, in the treatment of Class V carious lesions in vital teeth)                

2007 – 2008  Osspray industrial grant – clinical trial of bioglass densensitisation using air-abrasion.        
(PI / chief investigator of the clinical trial run at KCLDI investigating the use of bio-active glass in desensitizing teeth – 2 publications).

 2009 – 2014   Wellcome/EPSRC: KCL Medical Engineering Centre, Rebuilding Faces.
(Co-applicant / Lead for Work package 3.5 – translational clinical research into patient treatment of oral diseases)

2010 – 2011    GSTFT Charity New Services and Innovations Grant – Salivaguard: an intra-oral lubrication system for patient with xerostomia   
(Co-PI (Cook RJ, Watson TF, Fenlon M) to develop as proof-of-concept, a novel intraoral lubricating appliance for patients with xerostomia).

2010 – 2011    NIHR i4i FPD3a; II-3A-1109-10046: Operative caries management system.   
(Co-PI (Watson TF, Thompson I) – co-wrote application for post- doctoral funding, as supervisor).

2010 - 2014     Septodont USA commercial grant (NRCWUBR): In-vitro characterization of the physico / chemo-mechanical properties of a nano-dimer resin adhesives and their interaction with sound tooth structure.   
(PI – developed / wrote research proposal with commercial partner, funding a PhD student, first supervisor).

2011 – 2014    GSTT Charity New Services and Innovations Grant – Prevention of aggressive radiotherapy-induced dental decay in head and neck cancer patients.(S100904) 
(PI co-ordinating a clinical trial on head and neck cancer patients using oral xylitol intervention for reducing radiation-induced dental caries).

2012 - 2015     Septodont France commercial grant: An in-vivo evaluation of the efficacy of tricalcium silicate restorative material as a pulp capping agent; a randomized controlled clinical trial (NRCVUAR)    
(PI – developed / wrote research proposal with commercial partner, funding a PhD student – supervisor of RCT).

2014                GSK - Development of a co-localised Raman and fluorescence lifetime imaging platform.    
(Co-PI with F Festy)

 2015 – 2018    GSK - Therapeutic remineralisation of dental porosities, doctorate studentship.        (PI & first supervisor with TF Watson, R Lynch (GSK). I was responsible for developing the grant proposal/application and negotiating terms with industry)

 2016 – 2017    3M – Clinical post-market follow up of the desensitization efficacy of a new TCP-containing varnish – practice-based clinical research grant          
(PI & first supervisor; PBR grant for MSc AMID students – responsible for attracting and negotiating terms / protocol development with industry partners)

 2017 – 2018    King’s College Innovations (KCI Health Accelerator funding) – Remineralisation and desensitisation of teeth with a novel biocompatible chemistry.       
(Co-PI with S Deb, TF Watson & G Koller. Developed protocol and responsible for supervision of post-doc and clinical trial, investigating a novel calcium phosphate delivery within dental tissue porosities)

 2017 – 2018    Wrigley’s commercial project grant (G16005) – systematic review on the efficacy of sugar-free gum on oral health.     
(PI – head of team, developed link and protocol with Wrigley’s)

 2018                3M Oral Care commercial research grant – In-vitro mechanical studies on Ketac Universal GIC vs. other materials            
(PI – employing RA for in-vitro studies – 6 mths)

2018-2019       Unilever commercial grant: Remineralising Effects of Experimental Treatments on Enamel White Spot Lesions In Vitro (G18016)        
(PI – developed and negotiated research proposal and contract to employ PDRA for 6 mth in-vitro studies)

2019 – 2022    NIHR HTA Reference Number: 17/127/07 - Selective Caries Removal in Permanent Teeth (SCRIPT)    
(Co-applicant & Clinical Lead for London / SE in a national clinical trial with Dundee, Aberdeen CTU and Sheffield)

2019 - 2020     Unilever commercial grant extension: Remineralising Effects of Experimental Treatments on Enamel White Spot Lesions In Vitro (G18016)       
(PI – developed and negotiated research proposal and contract to employ PDRA for a further 6 mth in-vitro studies)

2019 – 2020    3M Oral Care commercial research grant (G18022) – In-vitro investigation of the interfacial characteristics and micro-shear strength of a self-adhesive bio-interactive material, ‘Monarch’, with sound/demineralised dentine.  
(PI – employing PDRA for in-vitro studies – 6 mths)