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Research on Cariology & minimum intervention / minimally invasive operative dentistry: cariogenic biofilm microbiome, remineralisation, biochemical carious tissue analysis, caries detection, MI operative management / selective caries removal technologies, bio-interactive materials’ interfaces, clinical trials (dental anxiety, Head & Neck cancer, paediatrics, caries excavation), digital education, SRs and social media studies.

Hand piece

Publications

    Awards

    1995 - 1998   Medical Research Council Clinical Training Fellowship G84/4339).    
    (Co-PI (Watson TF, Kidd EAM) –planned and co-wrote application for funding my doctoral research studies – resulted in award of PhD, 6 publications)  

    1997 - 2009     Consultancy grants from Mediteam / Orasolv (Sweden) for independent, experimental, evaluation of CarisolvTM.   
    (Clinical and lab studies chief investigator – resulted in three publications)                                                                          

    2001 - 2002     Charitable Foundation grant (R001145), Guy's, King's and St. Thomas' Dental Institute: Molecular quantitation, species diversity and 3-dimensional distribution of the microflora in human carious dentine.                                 
    (PI (Wade W, Watson TF) –funded a post-doc – 2 publications.                             

    2002 - 2006     Engineering & Physical Sciences Research Council (EPSRC) (GR/R66906/01).  Bioactive Air-abrasion in Restorative Dentistry:  development and high-speed confocal microscopic assessment.   
    (Co-PI (Watson TF, Sherriff M) – co-wrote the application which funded a PG doctoral student which I supervised – 5 publications).

    2006 - 2007     3MESPE Industrial grant - In-vitro investigation of the efficacy of an enzymatic caries removal system, Biosolv™.                                                                            
    (Chief Investigator running a clinical trial (European, multi-centre, RCT) of SFC-V, an enzymatic dentine caries removal system, in the treatment of Class V carious lesions in vital teeth)                

    2007 – 2008  Osspray industrial grant – clinical trial of bioglass densensitisation using air-abrasion.        
    (PI / chief investigator of the clinical trial run at KCLDI investigating the use of bio-active glass in desensitizing teeth – 2 publications).

     2009 – 2014   Wellcome/EPSRC: KCL Medical Engineering Centre, Rebuilding Faces.
    (Co-applicant / Lead for Work package 3.5 – translational clinical research into patient treatment of oral diseases)

    2010 – 2011    GSTFT Charity New Services and Innovations Grant – Salivaguard: an intra-oral lubrication system for patient with xerostomia   
    (Co-PI (Cook RJ, Watson TF, Fenlon M) to develop as proof-of-concept, a novel intraoral lubricating appliance for patients with xerostomia).

    2010 – 2011    NIHR i4i FPD3a; II-3A-1109-10046: Operative caries management system.   
    (Co-PI (Watson TF, Thompson I) – co-wrote application for post- doctoral funding, as supervisor).

    2010 - 2014     Septodont USA commercial grant (NRCWUBR): In-vitro characterization of the physico / chemo-mechanical properties of a nano-dimer resin adhesives and their interaction with sound tooth structure.   
    (PI – developed / wrote research proposal with commercial partner, funding a PhD student, first supervisor).

    2011 – 2014    GSTT Charity New Services and Innovations Grant – Prevention of aggressive radiotherapy-induced dental decay in head and neck cancer patients.(S100904) 
    (
    PI co-ordinating a clinical trial on head and neck cancer patients using oral xylitol intervention for reducing radiation-induced dental caries).

    2012 - 2015     Septodont France commercial grant: An in-vivo evaluation of the efficacy of tricalcium silicate restorative material as a pulp capping agent; a randomized controlled clinical trial (NRCVUAR)    
    (PI – developed / wrote research proposal with commercial partner, funding a PhD student – supervisor of RCT).

    2014                GSK - Development of a co-localised Raman and fluorescence lifetime imaging platform.    
    (Co-PI with F Festy)

     2015 – 2018    GSK - Therapeutic remineralisation of dental porosities, doctorate studentship.        (PI & first supervisor with TF Watson, R Lynch (GSK). I was responsible for developing the grant proposal/application and negotiating terms with industry)

     2016 – 2017    3M – Clinical post-market follow up of the desensitization efficacy of a new TCP-containing varnish – practice-based clinical research grant          
    (PI & first supervisor; PBR grant for MSc AMID students – responsible for attracting and negotiating terms / protocol development with industry partners)

     2017 – 2018    King’s College Innovations (KCI Health Accelerator funding) – Remineralisation and desensitisation of teeth with a novel biocompatible chemistry.       
    (Co-PI with S Deb, TF Watson & G Koller. Developed protocol and responsible for supervision of post-doc and clinical trial, investigating a novel calcium phosphate delivery within dental tissue porosities)

     2017 – 2018    Wrigley’s commercial project grant (G16005) – systematic review on the efficacy of sugar-free gum on oral health.     
    (PI – head of team, developed link and protocol with Wrigley’s)

     2018                3M Oral Care commercial research grant – In-vitro mechanical studies on Ketac Universal GIC vs. other materials            
    (PI – employing RA for in-vitro studies – 6 mths)

    2018-2019       Unilever commercial grant: Remineralising Effects of Experimental Treatments on Enamel White Spot Lesions In Vitro (G18016)        
    (
    PI – developed and negotiated research proposal and contract to employ PDRA for 6 mth in-vitro studies)

    2019 – 2022    NIHR HTA Reference Number: 17/127/07 - Selective Caries Removal in Permanent Teeth (SCRIPT)    
    (Co-applicant & Clinical Lead for London / SE in a national clinical trial with Dundee, Aberdeen CTU and Sheffield)

    2019 - 2020     Unilever commercial grant extension: Remineralising Effects of Experimental Treatments on Enamel White Spot Lesions In Vitro (G18016)       
    (PI – developed and negotiated research proposal and contract to employ PDRA for a further 6 mth in-vitro studies)

    2019 – 2020    3M Oral Care commercial research grant (G18022) – In-vitro investigation of the interfacial characteristics and micro-shear strength of a self-adhesive bio-interactive material, ‘Monarch’, with sound/demineralised dentine.  
    (PI – employing PDRA for in-vitro studies – 6 mths)

    AMID

    The research programme is closely linked to post-graduate dental education. Professor Banerjee has developed and run a distance-learning (blended learning) 3 year masters course in Advanced Minimum Intervention Dentistry (AMID) at King's.

    This course enables dental practitioners and dental therapists the opportunity to learn about minimum intervention oral healthcare and changing their delivery of care to a more patient-focused, team-delivered approach emphasising the prevention of disease and maintenance of oral health. It allows practice-based clinicians to carry our clinical research projects (often dental industry funded), to form a practice-based clinical research network nationally and internationally.

    https://www.kcl.ac.uk/study/postgraduate/taught-courses/advanced-minimum-intervention-dentistry-msc

    Publications

      Awards

      1995 - 1998   Medical Research Council Clinical Training Fellowship G84/4339).    
      (Co-PI (Watson TF, Kidd EAM) –planned and co-wrote application for funding my doctoral research studies – resulted in award of PhD, 6 publications)  

      1997 - 2009     Consultancy grants from Mediteam / Orasolv (Sweden) for independent, experimental, evaluation of CarisolvTM.   
      (Clinical and lab studies chief investigator – resulted in three publications)                                                                          

      2001 - 2002     Charitable Foundation grant (R001145), Guy's, King's and St. Thomas' Dental Institute: Molecular quantitation, species diversity and 3-dimensional distribution of the microflora in human carious dentine.                                 
      (PI (Wade W, Watson TF) –funded a post-doc – 2 publications.                             

      2002 - 2006     Engineering & Physical Sciences Research Council (EPSRC) (GR/R66906/01).  Bioactive Air-abrasion in Restorative Dentistry:  development and high-speed confocal microscopic assessment.   
      (Co-PI (Watson TF, Sherriff M) – co-wrote the application which funded a PG doctoral student which I supervised – 5 publications).

      2006 - 2007     3MESPE Industrial grant - In-vitro investigation of the efficacy of an enzymatic caries removal system, Biosolv™.                                                                            
      (Chief Investigator running a clinical trial (European, multi-centre, RCT) of SFC-V, an enzymatic dentine caries removal system, in the treatment of Class V carious lesions in vital teeth)                

      2007 – 2008  Osspray industrial grant – clinical trial of bioglass densensitisation using air-abrasion.        
      (PI / chief investigator of the clinical trial run at KCLDI investigating the use of bio-active glass in desensitizing teeth – 2 publications).

       2009 – 2014   Wellcome/EPSRC: KCL Medical Engineering Centre, Rebuilding Faces.
      (Co-applicant / Lead for Work package 3.5 – translational clinical research into patient treatment of oral diseases)

      2010 – 2011    GSTFT Charity New Services and Innovations Grant – Salivaguard: an intra-oral lubrication system for patient with xerostomia   
      (Co-PI (Cook RJ, Watson TF, Fenlon M) to develop as proof-of-concept, a novel intraoral lubricating appliance for patients with xerostomia).

      2010 – 2011    NIHR i4i FPD3a; II-3A-1109-10046: Operative caries management system.   
      (Co-PI (Watson TF, Thompson I) – co-wrote application for post- doctoral funding, as supervisor).

      2010 - 2014     Septodont USA commercial grant (NRCWUBR): In-vitro characterization of the physico / chemo-mechanical properties of a nano-dimer resin adhesives and their interaction with sound tooth structure.   
      (PI – developed / wrote research proposal with commercial partner, funding a PhD student, first supervisor).

      2011 – 2014    GSTT Charity New Services and Innovations Grant – Prevention of aggressive radiotherapy-induced dental decay in head and neck cancer patients.(S100904) 
      (
      PI co-ordinating a clinical trial on head and neck cancer patients using oral xylitol intervention for reducing radiation-induced dental caries).

      2012 - 2015     Septodont France commercial grant: An in-vivo evaluation of the efficacy of tricalcium silicate restorative material as a pulp capping agent; a randomized controlled clinical trial (NRCVUAR)    
      (PI – developed / wrote research proposal with commercial partner, funding a PhD student – supervisor of RCT).

      2014                GSK - Development of a co-localised Raman and fluorescence lifetime imaging platform.    
      (Co-PI with F Festy)

       2015 – 2018    GSK - Therapeutic remineralisation of dental porosities, doctorate studentship.        (PI & first supervisor with TF Watson, R Lynch (GSK). I was responsible for developing the grant proposal/application and negotiating terms with industry)

       2016 – 2017    3M – Clinical post-market follow up of the desensitization efficacy of a new TCP-containing varnish – practice-based clinical research grant          
      (PI & first supervisor; PBR grant for MSc AMID students – responsible for attracting and negotiating terms / protocol development with industry partners)

       2017 – 2018    King’s College Innovations (KCI Health Accelerator funding) – Remineralisation and desensitisation of teeth with a novel biocompatible chemistry.       
      (Co-PI with S Deb, TF Watson & G Koller. Developed protocol and responsible for supervision of post-doc and clinical trial, investigating a novel calcium phosphate delivery within dental tissue porosities)

       2017 – 2018    Wrigley’s commercial project grant (G16005) – systematic review on the efficacy of sugar-free gum on oral health.     
      (PI – head of team, developed link and protocol with Wrigley’s)

       2018                3M Oral Care commercial research grant – In-vitro mechanical studies on Ketac Universal GIC vs. other materials            
      (PI – employing RA for in-vitro studies – 6 mths)

      2018-2019       Unilever commercial grant: Remineralising Effects of Experimental Treatments on Enamel White Spot Lesions In Vitro (G18016)        
      (
      PI – developed and negotiated research proposal and contract to employ PDRA for 6 mth in-vitro studies)

      2019 – 2022    NIHR HTA Reference Number: 17/127/07 - Selective Caries Removal in Permanent Teeth (SCRIPT)    
      (Co-applicant & Clinical Lead for London / SE in a national clinical trial with Dundee, Aberdeen CTU and Sheffield)

      2019 - 2020     Unilever commercial grant extension: Remineralising Effects of Experimental Treatments on Enamel White Spot Lesions In Vitro (G18016)       
      (PI – developed and negotiated research proposal and contract to employ PDRA for a further 6 mth in-vitro studies)

      2019 – 2020    3M Oral Care commercial research grant (G18022) – In-vitro investigation of the interfacial characteristics and micro-shear strength of a self-adhesive bio-interactive material, ‘Monarch’, with sound/demineralised dentine.  
      (PI – employing PDRA for in-vitro studies – 6 mths)

      AMID

      The research programme is closely linked to post-graduate dental education. Professor Banerjee has developed and run a distance-learning (blended learning) 3 year masters course in Advanced Minimum Intervention Dentistry (AMID) at King's.

      This course enables dental practitioners and dental therapists the opportunity to learn about minimum intervention oral healthcare and changing their delivery of care to a more patient-focused, team-delivered approach emphasising the prevention of disease and maintenance of oral health. It allows practice-based clinicians to carry our clinical research projects (often dental industry funded), to form a practice-based clinical research network nationally and internationally.

      https://www.kcl.ac.uk/study/postgraduate/taught-courses/advanced-minimum-intervention-dentistry-msc

      Our Partners

      University of Dundee

      University of Dundee

      Group lead

      Contact us

      Professor Avijit Banerjee
      Centre for Oral Clinical & Translational Sciences

      Guy's Tower Wing
      Guy's Hospital