Defining cell behaviour of human iPS cells using high content imaging
This work started within the framework of the Human induced pluripotent stem cells intiative (HipSci). More recently, phd student Haneen Alsehli has been studying iPS forming sheroids using high content analysis and artificial microenvironments to define inter-relationships between morphology of these structures and lineage differentiation.
Haneen Alsehli – Human iPS form spheroids in self-renewing (left) and differentiating (right) conditions (blue, nuclei – red, phalloidin – gray, 3D reconstruction)