South London Stroke Register (SLSR) The South London Stroke Register is the world’s longest running, population-based stroke register with long term follow up. Data and trials from the SLSR have underpinned improvements in acute stroke care and rehabilitation in the UK, which have led to reduced stroke death and disability, better long-term health outcomes, and cost savings for the NHS. The SLSR was set up by Professor Charles Wolfe to provide reliable information about the numbers of strokes occurring and the immediate and long-term consequences of the disease, to assess the quality of stroke care, and to test new ways of providing care. Since 1995, the SLSR has been recording and following up all first-ever strokes in people of all ages living in Lambeth and Southwark, inner city South London, a well-defined multi-ethnic population. Information has been collected on over 7,000 patients who are followed up at three months and annually after stroke, for life.