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Research into Improvement of Outcome of Fertility Treatment

Current research projects primarily involve clinic-based research, systematic reviews and basic research.

Clinic-based research

  • Association between presences of uterine fibroids and outcome of assisted conception (prospective studies and systematic review) and effect of removal of fibroids prior to IVF on treatment outcome (RCT)
  • Antibiotics prophylaxis prior to embryo transfer and its effect on IVF treatment outcome (RCT)
  • Study of the effect of demographic characteristics on the reported outcome of IVF treatment (prospective cohort study)
  • Factors that affect the outcome of frozen-thawed embryo transfer (RCT/prospective studies)
  • Utilisation of extended embryo culture to reduce multiple birth (Prospective study)
  • Study of progesterone supplementation for management of unexplained recurrent pregnancy loss (‘PROMISE’, RCT, MRC funded)
  • Study of the factors that influence the risk of miscarriage following elective single blastocyst transfer (prospective study)
  • Study of luteal phase support using subcutaneous progesterone (RCT)

Systematic reviews and randomised control trials (RCT)

  • Study of the value of out-patient hysteroscopy in management of unexplained recurrent IVF failure (systematic review and RCT)
  • Study of the different ovarian stimulation regimes for poor responders (‘PRINT’,systematic review and RCT)
  • Study of the effect of acupuncture on the outcome of IVF treatment (systematic review)

Basic research

  • Development of reliable methods of ovarian tissue preservation that will allow patients who cannot afford to delay their cancer treatment to have an option of fertility preservation within 24-48 hours.
  • Biology and reproductive competence of human preimplantation embryos
  • Development of new models and tools for assisted conception technology research

The Group