Epithelial Bending in mammalian morphogenesis Epithelial bending is an important morphogenetic process and many birth defects arise from its failure. This project examines epithelial bending during the formation of ectodermal organs including teeth, salivary glands, hair follicles and mammary ducts in the mouse. These organs serve as models for other bending events during embryogenesis as well as having clinical relevance in their own right. The objective is to break down the complex morphogenetic processes that make these organs into their underlying cellular behaviours and then determine which signals and genes control those behaviours. The project exploits advanced microscopy, live explant imaging, genetics and chemical inhibition techniques.