We are interested in the molecular physiology of sarcomeric proteins driving and controlling heart muscle contraction and relaxation, how ablation or mutation of these proteins can lead to heart disease and heart failure, and the development of novel sarcomere-directed small molecule effectors.
Publications
Awards
Targeting the myofilaments to correct heart muscle dysfunction
BHF - British Heart Foundation
Kampourakis, T., Irving, M.
£215,446.00
28/01/2020 → 27/01/2023
Research Grant
Cardiac thick filament modulators: A potential new class of heart failure therapeutics
BHF - British Heart Foundation
Kampourakis, T., Irving, M.
£147,206.00
1/02/2018 → 30/04/2019
Research Grant
Myosin Binding Protein-C: a key regulator of cardiac output
BHF - British Heart Foundation
Kampourakis, T., Gautel, M., Irving, M.
£495,503.00
1/04/2016 → 31/03/2020
Research Grant Fellowship
Publications
Awards
Targeting the myofilaments to correct heart muscle dysfunction
BHF - British Heart Foundation
Kampourakis, T., Irving, M.
£215,446.00
28/01/2020 → 27/01/2023
Research Grant
Cardiac thick filament modulators: A potential new class of heart failure therapeutics
BHF - British Heart Foundation
Kampourakis, T., Irving, M.
£147,206.00
1/02/2018 → 30/04/2019
Research Grant
Myosin Binding Protein-C: a key regulator of cardiac output
BHF - British Heart Foundation
Kampourakis, T., Gautel, M., Irving, M.
£495,503.00
1/04/2016 → 31/03/2020
Research Grant Fellowship
Our Partners
British Heart Foundation
Group lead
Thomas Kampourakis
BHF Research Fellow and Lecturer