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We are interested in the molecular physiology of sarcomeric proteins driving and controlling heart muscle contraction and relaxation, how ablation or mutation of these proteins can lead to heart disease and heart failure, and the development of novel sarcomere-directed small molecule effectors.

Publications

    Awards

    Targeting the myofilaments to correct heart muscle dysfunction

    BHF - British Heart Foundation
    Kampourakis, T., Irving, M.
    £215,446.00
    28/01/2020 → 27/01/2023
    Research Grant

    Cardiac thick filament modulators: A potential new class of heart failure therapeutics

    BHF - British Heart Foundation
    Kampourakis, T., Irving, M.
    £147,206.00
    1/02/2018 → 30/04/2019
    Research Grant

    Myosin Binding Protein-C: a key regulator of cardiac output

    BHF - British Heart Foundation
    Kampourakis, T., Gautel, M., Irving, M.
    £495,503.00
    1/04/2016 → 31/03/2020
    Research Grant Fellowship

    Publications

      Awards

      Targeting the myofilaments to correct heart muscle dysfunction

      BHF - British Heart Foundation
      Kampourakis, T., Irving, M.
      £215,446.00
      28/01/2020 → 27/01/2023
      Research Grant

      Cardiac thick filament modulators: A potential new class of heart failure therapeutics

      BHF - British Heart Foundation
      Kampourakis, T., Irving, M.
      £147,206.00
      1/02/2018 → 30/04/2019
      Research Grant

      Myosin Binding Protein-C: a key regulator of cardiac output

      BHF - British Heart Foundation
      Kampourakis, T., Gautel, M., Irving, M.
      £495,503.00
      1/04/2016 → 31/03/2020
      Research Grant Fellowship

      Our Partners

      BHF

      British Heart Foundation