Lymphoma Signalling

The Lymphoma Signalling lab is led by Dr Robbert Hoogeboom. Dr Hoogeboom’s work focuses on the role of antigen exposure and B cell receptor signalling in the pathogenesis and treatment of B cell leukaemia and lymphoma. His team uses high content imaging of primary patient cells and novel in vivo mouse models to study the context in which malignant B cells see antigen and how antigen stimulation and BCR signalling influence the behaviour of the tumour cells and disease progression.