The Pfuhl group studies the structures of proteins and their dynamics and interactions using NMR spectroscopy and other biophysical techniques. We have two main areas of interest: The regulation of muscle contraction and what happens in muscle and cardiovascular disease and the regulation of protein kinases and their partner proteins in cancer. We study the relevant proteins to understand the molecular mechanisms that lead to disease and try to harness this understanding to support the development of new therapies.
Research in the group funded by the British Heart Foundation and the BBSRC.
British Heart Foundation
Biotechnology & Biological Sciences Research Council