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Programme in Gastrointestinal Cancer

The Programme in Gastrointestinal (GI) Cancer is part of the School of Cancer and Pharmaceutical Sciences at King's College London (KCL). It includes research into many diseases of the gastrointestinal tract, although most research is directed towards cancer, oesophago-gastric cancer in particular, and associated conditions. Cancer of the oesophagus or stomach is characterised by a poor overall prognosis. The main curative treatment is demanding, and includes extensive surgery. A high proportion of these patients present with advanced disease that precludes curative treatment, but with improvements in diagnostics, staging and management, the 5-year survival following surgery now reaches 50% in specialist centres.

The Upper Gastrointestinal Department at Guy’s & St Thomas’ Foundation Trust (GSTT) is one of the highest volume centres in Europe for the management of oesophageal and gastric cancer. Recent advances in oncology (peri-operative chemotherapy), surgery (centralisation, enhanced recovery, minimally-invasive surgery) and multi-disciplinary working (anaesthetics, gastroenterology, radiology, dietetics, physiotherapy, specialist nursing) have improved patient outcomes. The Programme in GI Cancer spans a broad field of interests and strongly promotes collaborative working, within KCL, nationally and internationally.

Group lead


Professor Jesper Lagergren

Professor of Upper Gastrointestinal Cancer and Honorary Consultant Surgeon